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The map label for this gene is maeN [H]

Identifier: 222094330

GI number: 222094330

Start: 634984

End: 636096

Strand: Direct

Name: maeN [H]

Synonym: BCQ_0644

Alternate gene names: 222094330

Gene position: 634984-636096 (Clockwise)

Preceding gene: 222094329

Following gene: 222094331

Centisome position: 12.18

GC content: 37.29

Gene sequence:

>1113_bases
ATGAGAATTCCAATTTTAAAAAATATCGGTGGTCCAGCAATACTTTCGTTGTTTATTCCATCATTACTTGTATTTTTTAA
CTGGATGAATCCAGCTTCAATGGAAGCTGCGACTATGTTAATGAAAAAATCGAACTTTTTATATTTATATATTTCTTGTT
TAGTAGTCGGAAGTATTTTAGGAATGAATCGTAAAGTATTAGTGCAAGGTTTCGTTCGTATGTTTATACCTTTAGTGGTA
GGGACGTTAGCTTCTGTAGTAGTAGGATTATTGGTCGGTTCACTATTTGGATTTGAAATGAAGCAAACATTCTTCTTTAT
CATCGTACCAATTGTGAGTGGTGGTATCGGGGAAGGGATTTTACCATTGTCGCTAGCTTATAGTGATATTTTAAATGAAT
CATCAGCAACATTTGTATCACAGCTTATTCCAGCGGCTATTATTGGAAATATGTTCGCTATCGTGAGTGCAGGGTATATG
AAGCGTTTAGGTGAGAAGAAACCGGAGCTTAGTGGTAACGGTGTATTAGTAAAAACAGACAATCAAGCCGAGTTATTAAA
AGAACAAAATACAGAGAAGCCAATTGACTTCTCATTAATGGGAGCAGGTTTATTAATTGCGTGTACGTTCTTCATCTTCG
GAGGATTTGCTTCTAAGTTCATCGGTATTCCTGGGGCAATCATTATGATCTTCTCAGCAGCACTTGTGAAATACTTTAAA
TTAATGCCAGCAAAAATGGAGCAAGGAGCATTCCATCTATATAAATTCATTTCGAAGAATTTAACTTGGCCTTTAATGGT
TGGACTAGGATTACTATATATTCCGCTAAAAGACGTAGCAGCAGTTCTTTCAGTGGGATATGTTGTCGTGTGCGCATCAG
TTGTTCTTACAATGGTAGCATCAGGTTTCCTTGTAGGGAAAGTGATGAAGATGTATCCGGTTGAATCAGCAATTGTAACT
GGATGCCATAGTGGTTTAGGTGGAACTGGAGATGTTGCTATTTTATCGGCTTCAAATCGTATGGAATTAATGCCGTTCGC
GCAAATTTCGACTCGTTTAGGCGGAGCGGCAATGGTTGTAACGGCGACAATATTATTAAAAATGTTTTCATGA

Upstream 100 bases:

>100_bases
TATTATTTATGGGGCATCTGTATATAATAAATTGCCAGCAGATATGATTGGTGGATTTGCAGTTATTATGATTATGGGTA
TTTTCTTAGGAGACATTGGG

Downstream 100 bases:

>100_bases
TCAAACAAGCTAGCTATATTCATATAGCTAGCTTGTCAAATTAAGGGGAGATTATAAGTATGTTAGAGAATCAAATTAAT
GAAAGATCATTGTTATTGCA

Product: Na+/malate symporter

Products: NA

Alternate protein names: Sodium-dependent malate transporter [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVV
GTLASVVVGLLVGSLFGFEMKQTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYM
KRLGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFK
LMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFLVGKVMKMYPVESAIVT
GCHSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS

Sequences:

>Translated_370_residues
MRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVV
GTLASVVVGLLVGSLFGFEMKQTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYM
KRLGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFK
LMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFLVGKVMKMYPVESAIVT
GCHSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS
>Mature_370_residues
MRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVV
GTLASVVVGLLVGSLFGFEMKQTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYM
KRLGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFK
LMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFLVGKVMKMYPVESAIVT
GCHSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS

Specific function: Acts as a Na(+)-malate symporter, as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate [H]

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 39596; Mature: 39596

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSIL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GMNRKVLVQGFVRMFIPLVVGTLASVVVGLLVGSLFGFEMKQTFFFIIVPIVSGGIGEGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKRLGEKKPELSGNGVLVKTD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
NQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFK
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGFLVGKVMKMYPVESAIVTGCHSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECCCCCEECHHHHHHHHCCCHHHHH
TATILLKMFS
HHHHHHHHCC
>Mature Secondary Structure
MRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSIL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GMNRKVLVQGFVRMFIPLVVGTLASVVVGLLVGSLFGFEMKQTFFFIIVPIVSGGIGEGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKRLGEKKPELSGNGVLVKTD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
NQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFK
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGFLVGKVMKMYPVESAIVTGCHSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECCCCCEECHHHHHHHHCCCHHHHH
TATILLKMFS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10903309; 12949159 [H]