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The map label for this gene is llrF [H]

Identifier: 222094323

GI number: 222094323

Start: 626299

End: 626970

Strand: Direct

Name: llrF [H]

Synonym: BCQ_0637

Alternate gene names: 222094323

Gene position: 626299-626970 (Clockwise)

Preceding gene: 222094322

Following gene: 222094324

Centisome position: 12.01

GC content: 35.42

Gene sequence:

>672_bases
ATGCGCTTACTCGTAGTAGAAGATAATGCTTCCTTATTAGAGTCTATTGTCCAAATATTACGCGACGAATTTGAAGTAGA
TACAGCATTGAATGGAGAAGAGGGGTTATTTCTAGCGTTACAAAATATATATGATGCAATTTTGCTTGATGTGATGATGC
CAGAGATGGATGGTTTTGAAGTAATTCAAAGAATACGTGATGAAAAGATTGAAACACCAATCCTGTTTTTAACAGCGAGA
GATTCTTTAGAAGATCGGGTGAAGGGATTGGACTTTGGTGGAGATGACTATATCGTTAAGCCATTTCAGGCTCCAGAGTT
AAAAGCGAGAATTCGTGCTTTACTACGCAGAAGTGGTAATTTAACAACAAAGCAGACTATTCGATATAAAGGGATTGAAC
TGTTCGGAAAAGATAAAGATGTTCAAGTAGATGGACAAAGTATGAAGCTAACATTAAAACAATATGAGCTTCTAGAGTAC
CTTGTTCAAAATAGCGGAAAGATTTTAATGAGGGAACAAATTTTTGATCGTGTTTGGGGATTTGATTCAGATACGACAGT
GGCAATTGTAGAAGTGTATGTACATCATTTACGTAAAAAATTAGAGCCATTCGGTTATCAGAAAGATATTCAAACCGTTC
GAGGTATTGGATATATATTAAAAGAACAATGA

Upstream 100 bases:

>100_bases
AATTAAAAATGAAGTTACAAAATATGATTATATTCTTTTGTTAGGAAAAGCAGGAATGTGATTATAAATAGAATTGAATG
ATATGGTGGAAGGTGAGAAT

Downstream 100 bases:

>100_bases
AAAAGGGAAGTATGTTTCAGAAGACGCGCATTCGATTGACTATATTGAATTCATTAGTATTTATCATTTTGATAGGCGTA
TTAGGTAGTATCATTTATTC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRLLVVEDNASLLESIVQILRDEFEVDTALNGEEGLFLALQNIYDAILLDVMMPEMDGFEVIQRIRDEKIETPILFLTAR
DSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGNLTTKQTIRYKGIELFGKDKDVQVDGQSMKLTLKQYELLEY
LVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ

Sequences:

>Translated_223_residues
MRLLVVEDNASLLESIVQILRDEFEVDTALNGEEGLFLALQNIYDAILLDVMMPEMDGFEVIQRIRDEKIETPILFLTAR
DSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGNLTTKQTIRYKGIELFGKDKDVQVDGQSMKLTLKQYELLEY
LVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
>Mature_223_residues
MRLLVVEDNASLLESIVQILRDEFEVDTALNGEEGLFLALQNIYDAILLDVMMPEMDGFEVIQRIRDEKIETPILFLTAR
DSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGNLTTKQTIRYKGIELFGKDKDVQVDGQSMKLTLKQYELLEY
LVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ

Specific function: Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=40.4545454545455, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.7321428571429, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=37.0535714285714, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.5, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.5454545454545, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.2342342342342, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=35.1351351351351, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.7017543859649, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.1991341991342, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=30.9090909090909, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.3185840707965, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=191, Percent_Identity=32.9842931937173, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=30.8333333333333, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=91, Percent_Identity=35.1648351648352, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25790; Mature: 25790

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVVEDNASLLESIVQILRDEFEVDTALNGEEGLFLALQNIYDAILLDVMMPEMDGFE
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
VIQRIRDEKIETPILFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGN
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCC
LTTKQTIRYKGIELFGKDKDVQVDGQSMKLTLKQYELLEYLVQNSGKILMREQIFDRVWG
CCHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHC
FDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLLVVEDNASLLESIVQILRDEFEVDTALNGEEGLFLALQNIYDAILLDVMMPEMDGFE
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
VIQRIRDEKIETPILFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGN
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCC
LTTKQTIRYKGIELFGKDKDVQVDGQSMKLTLKQYELLEYLVQNSGKILMREQIFDRVWG
CCHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHC
FDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]