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The map label for this gene is purL [H]

Identifier: 222094053

GI number: 222094053

Start: 320522

End: 322741

Strand: Direct

Name: purL [H]

Synonym: BCQ_0346

Alternate gene names: 222094053

Gene position: 320522-322741 (Clockwise)

Preceding gene: 222094052

Following gene: 222094054

Centisome position: 6.15

GC content: 40.72

Gene sequence:

>2220_bases
ATGTCGTTAATGCTTGAACCAAATCCAACACAAATTAAAGAAGAGCGCATATATGCGGAAATGGGGCTAACAGACGAAGA
GTTTGCCATGGTTGAAAAGATTTTAGGCCGTCTGCCAAATTATACAGAAACAGGATTATTCTCTGTTATGTGGTCTGAAC
ATTGTAGTTATAAAAATTCAAAACCAGTGCTTCGAAAATTCCCAACAACAGGTGAGCGTGTCTTGCAAGGACCTGGGGAA
GGTGCTGGAATTGTAGACATCGGTGATAATCAAGCGGTTGTATTTAAAATGGAAAGTCATAACCACCCTTCTGCTATTGA
GCCATATCAAGGAGCAGCAACAGGTGTTGGTGGTATTATTCGTGACGTATTCTCTATGGGAGCACGCCCAGTCGCTCTAT
TAAACTCACTTCGATTTGGTGAATTACAATCACCACGTGTGAAATATTTATTTGAAGAAGTAGTAGCAGGAATTGCAGGA
TACGGTAACTGTATCGGTATTCCAACTGTTGGCGGCGAAGTACAGTTTGATCCATGTTATGAAGGAAATCCACTTGTAAA
TGCAATGTGCGTAGGCTTAATTAACCACGAGGACATTAAAAAAGGGCAAGCGCACGGTGCTGGAAATACAGTAATGTACG
TAGGAGCATCAACTGGTCGTGATGGTATCCACGGTGCAACATTCGCATCTGAAGAGTTATCTGAAAGCTCAGAAGCGAAG
CGTCCAGCAGTTCAAGTAGGAGATCCATTTATGGAGAAACTTCTTATCGAAGCTTGCTTAGAACTTATTCAATCGGATGC
ACTTGTTGGAATTCAAGATATGGGTGCGGCTGGTTTAACATCATCTTCTGCAGAAATGGCAAGTAAAGCAGGAATGGGTA
TTGAAATGTACTTAGATGATGTACCACAACGAGAAACAGGAATGACACCATATGAAATGATGCTCTCTGAATCACAAGAG
CGTATGTTAATTGTTGTGAAAAAAGGTAGAGAGCAAGAAATAGTAGATTTATTTGAGAAGTATGGTCTTGCAGCCGTTAC
GATGGGGAAAGTAACGGAAGACAAAATGCTTCGTTTATTCCATAAAGGTGAAATGGTAGCTGAAGTTCCAGCAGATGCTC
TTGCAGAAGAAGCGCCAATTTATCATAAACCATCACAAGAAGCAGCATACTTTGCTGAATTCCAGCAGATGAAAATGGAA
ACACCAAAAGTAGAAAATTATAAAGAAACGTTATTCGCCCTATTACAACAACCGACGATTGCAAGTAAAGAGTGGGTTTA
TGATCAATATGATTATCAAGTTCGCACAAGCACAGTTGTTACACCAGGTTCAGATGCAGCAGTTGTACGTGTACGCGGTA
CAGAAAAAGGATTAGCAATGACGACAGATTGTAACTCTCGCTACATTTATTTAGACCCAGAAGTGGGCGGTAAAATCGCA
GTAGCAGAGGCAGCACGTAATATCGTATGTTCTGGCGGGGAGCCACTTGCAATTACAGATTGCTTAAACTTCGGTAATCC
AGAGAAACCAGAAATTTTCTGGCAAATTGAGAAATCAGTAGATGGTATGAGTGAAGCTTGTCGCACATTACAAACACCAG
TTATTGGCGGAAACGTATCAATGTATAACGAACGTAGTGGTGAAGCGGTATATCCAACACCGACAGTTGGGATGGTCGGA
CTAGTACATGACTTAAAGCATGTAACAACACAAGAGTTTAAGCAAGCTGGCGATTTAGTTTATGTTATCGGAGAGACGAA
AGCTGAGTTTGGTGGAAGTGAATTACAGAAAATGCTTCACGGAAAAATTTTCGGACAATCACCAAGTATTGATCTAGACG
TAGAATTAAAGCGTCAAAAACAAATATTAGCAGCAATCCAAGCTGGCCTTGTTCAATCTGCACATGACGTTGCTGAAGGT
GGTTTAGCAGTTGCGATTTCAGAAAGTGCAATTGGTGCTAACGGCTTAGGTGCTACTGTGAAATTAGACGGGGAAGCAAC
AGCGGCATTATTTGCGGAATCACAATCTCGCTTCGTAATAACTGTAAAACGTGAAAATAAAGAAGCGTTCGAAAAAGCGG
TAGAAGCAATTCAAGTTGGAGAAGTAACAAATACAAATGAAGTGACAATTCATAATGAAGAAAATGAAGTATTACTTACA
GCAAATGTAGATGAAATGAGAAAGGCTTGGAAAGGGGCAATCCCATGCTTGCTGAAATAA

Upstream 100 bases:

>100_bases
GGTATGATGCCACACCCAGAGCGTGCTGTAGATGAATTACTTGGCGGTGCTGAAGGGTTAAAAGTCTTTCAATCTATCTT
AAAACAGTGGAGGGAAACAT

Downstream 100 bases:

>100_bases
AGGGGTTAAACGAAGAATGTGGCGTTTTCGGAATTTGGGGGCATGAAAATGCGGCACAAGTTTCATACTACGGATTGCAC
AGTTTACAGCACCGTGGACA

Product: phosphoribosylformylglycinamidine synthase ii

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKME
TPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEG
GLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK

Sequences:

>Translated_739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKME
TPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEG
GLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK
>Mature_738_residues
SLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEG
AGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGY
GNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKR
PAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQER
MLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKMET
PKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAV
AEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGL
VHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEGG
LAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTA
NVDEMRKAWKGAIPCLLK

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=720, Percent_Identity=24.4444444444444, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI48994899, Length=763, Percent_Identity=25.5570117955439, Blast_Score=139, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17553022, Length=683, Percent_Identity=21.9619326500732, Blast_Score=105, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321498, Length=723, Percent_Identity=22.8215767634855, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582111, Length=637, Percent_Identity=24.0188383045526, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24582109, Length=637, Percent_Identity=24.0188383045526, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17137292, Length=637, Percent_Identity=24.0188383045526, Blast_Score=103, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 80190; Mature: 80059

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNS
CCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLH
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATV
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEE
KLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNS
CEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLH
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATV
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEE
KLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA