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The map label for this gene is pabC [H]

Identifier: 222093841

GI number: 222093841

Start: 76420

End: 77292

Strand: Direct

Name: pabC [H]

Synonym: BCQ_0080

Alternate gene names: 222093841

Gene position: 76420-77292 (Clockwise)

Preceding gene: 222093840

Following gene: 222093842

Centisome position: 1.47

GC content: 35.62

Gene sequence:

>873_bases
ATGTTAATTTACGTAAATGGTCAGTATGTAGAATCGAGTGAAGCGAGAATTTCTCCTTATGATCATGGTTATTTATATGG
TCTTGGAGTTTTTGAGACTTTTCGTATTTATAATGGTCATCCTTTCTTATTGGATGATCATTATGACCGTTTAATAGATG
CGCTGGATACATTGCAAATAAAATGGACAATGACGAAAGATGAAGTAATGCTTATTTTGAAGAATTTAATCGTTAAGAAT
AAATTAGAGCATGCGTATGTCCGTTTTAATGTATCGGCGGGTATAGATGAAATTGGATTGCAAACAGAAATGTATGAAGA
GCCGTCTATTATTGTTTTTATAAAACCTTTAGCGGCCCCGGGAGATGTAGTGGAAAAAGAAGGGGTTGTCTTAAATCAAG
TGAGAAATACCCCAGAGGGTGCATCTCGCTTGAAGTCTCACCATTATTTAAATAACATTTTGGGGAAACGTGAAATTGGA
AATGGTGTGAATAAGGAAGGGATTTTCCTGACTGAAGTAGGTTATGTTGCAGAGGGTATTGTTTCGAATCTCTTTTTTGT
GAAAGGTGATATTTTATATACACCTTCGCTTGAAACAGGGATTTTAAATGGTATCACTCGTGCGTTTATTATAAAGGTTG
CTGAAGAGATTGGTATAGAAGTAAAAGAAGGTTTCTTTACAAAAGATGAATTACTTTCAGCCGATGAAGTCTTCGTAACA
AACTCGATTCAAGAAATTGTTCCGCTTAATCGTATAGAGGGACGAGATTTCCCGGGTAAAGTAGGTATGGTTACAAAAAG
ATTTATGAACCTTTATGAAATGCAGAGAGAGAAATTGTGGAGCAGAAATGAATTACGAAGAGGAGATGTGTAG

Upstream 100 bases:

>100_bases
CGATTGAAGGTGTGCAGTTCCACCCGGAATCTATTATGACTTCTCACGGGAAAGAGTTGTTGCAGAATTTCATTCGTAAA
TATAGTCCAAGTGTGACATC

Downstream 100 bases:

>100_bases
TTTGAAGTGGGATTATGATTTGCGCTGCGGCGAATATACATTGAACTTAAATGAAAAAACGTTAATTATGGGGATTTTAA
ATGTAACACCAGATTCGTTT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLIYVNGQYVESSEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVMLILKNLIVKN
KLEHAYVRFNVSAGIDEIGLQTEMYEEPSIIVFIKPLAAPGDVVEKEGVVLNQVRNTPEGASRLKSHHYLNNILGKREIG
NGVNKEGIFLTEVGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEEIGIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEGRDFPGKVGMVTKRFMNLYEMQREKLWSRNELRRGDV

Sequences:

>Translated_290_residues
MLIYVNGQYVESSEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVMLILKNLIVKN
KLEHAYVRFNVSAGIDEIGLQTEMYEEPSIIVFIKPLAAPGDVVEKEGVVLNQVRNTPEGASRLKSHHYLNNILGKREIG
NGVNKEGIFLTEVGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEEIGIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEGRDFPGKVGMVTKRFMNLYEMQREKLWSRNELRRGDV
>Mature_290_residues
MLIYVNGQYVESSEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVMLILKNLIVKN
KLEHAYVRFNVSAGIDEIGLQTEMYEEPSIIVFIKPLAAPGDVVEKEGVVLNQVRNTPEGASRLKSHHYLNNILGKREIG
NGVNKEGIFLTEVGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEEIGIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEGRDFPGKVGMVTKRFMNLYEMQREKLWSRNELRRGDV

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=293, Percent_Identity=31.740614334471, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787338, Length=255, Percent_Identity=27.0588235294118, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 33013; Mature: 33013

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYVNGQYVESSEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEEHHHHEEEEECCCEEEECCHHHHHHHHHHCEEE
KWTMTKDEVMLILKNLIVKNKLEHAYVRFNVSAGIDEIGLQTEMYEEPSIIVFIKPLAAP
EEEECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GDVVEKEGVVLNQVRNTPEGASRLKSHHYLNNILGKREIGNGVNKEGIFLTEVGYVAEGI
CCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEEHHHHHHHH
VSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEEIGIEVKEGFFTKDELLSADEVFVT
HHHHHEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHCCCCCEEEC
NSIQEIVPLNRIEGRDFPGKVGMVTKRFMNLYEMQREKLWSRNELRRGDV
CCHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCC
>Mature Secondary Structure
MLIYVNGQYVESSEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEEHHHHEEEEECCCEEEECCHHHHHHHHHHCEEE
KWTMTKDEVMLILKNLIVKNKLEHAYVRFNVSAGIDEIGLQTEMYEEPSIIVFIKPLAAP
EEEECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GDVVEKEGVVLNQVRNTPEGASRLKSHHYLNNILGKREIGNGVNKEGIFLTEVGYVAEGI
CCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEEHHHHHHHH
VSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEEIGIEVKEGFFTKDELLSADEVFVT
HHHHHEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHCCCCCEEEC
NSIQEIVPLNRIEGRDFPGKVGMVTKRFMNLYEMQREKLWSRNELRRGDV
CCHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]