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The map label for this gene is pabA [H]

Identifier: 222093840

GI number: 222093840

Start: 75839

End: 76426

Strand: Direct

Name: pabA [H]

Synonym: BCQ_0079

Alternate gene names: 222093840

Gene position: 75839-76426 (Clockwise)

Preceding gene: 222093839

Following gene: 222093841

Centisome position: 1.45

GC content: 39.29

Gene sequence:

>588_bases
ATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACAAGATCTTGT
TGTTAAACGTAACGATGAAGTGACTATTTCAGATATTGAGAATATGAAACCAGACTTTTTAATGATTTCGCCAGGTCCAT
GTAGTCCGAATGAGGCAGGAATTAGTATGGAAGTTATTCGATACTTTGCTGGAAAGATTCCGATTTTTGGGGTTTGTCTC
GGGCATCAATCTATTGCGCAAGTGTTTGGTGGAGAGGTTGTTCGTGCAGAGCGATTAATGCATGGGAAAACATCGCTTAT
GCATCATGATGAGAAGACGATTTTTTCGGATATCCCTAATCCGTTTACCGCGACGCGCTATCATTCCCTTATTGTTAAGA
AAGAGACGTTACCTGATTGTTTAGAGGTAACGTCTTGGACAGAAGAAGGGGAAATTATGGCGCTCCGCCATACAACATTA
CCGATTGAAGGTGTGCAGTTCCACCCGGAATCTATTATGACTTCTCACGGGAAAGAGTTGTTGCAGAATTTCATTCGTAA
ATATAGTCCAAGTGTGACATCATGTTAA

Upstream 100 bases:

>100_bases
TTGATTCAAATCCGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTATGGCGTGCAAAAGAACGTAGTGAA
GAAACGGTTAGGTGAGAGAA

Downstream 100 bases:

>100_bases
TTTACGTAAATGGTCAGTATGTAGAATCGAGTGAAGCGAGAATTTCTCCTTATGATCATGGTTATTTATATGGTCTTGGA
GTTTTTGAGACTTTTCGTAT

Product: para-aminobenzoate/anthranilate synthase glutamine amidotransferase component ii

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MILMIDNYDSFTFNLVQFLGELGQDLVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEVIRYFAGKIPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDEKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC

Sequences:

>Translated_195_residues
MILMIDNYDSFTFNLVQFLGELGQDLVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEVIRYFAGKIPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDEKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC
>Mature_195_residues
MILMIDNYDSFTFNLVQFLGELGQDLVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEVIRYFAGKIPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDEKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=57.7540106951872, Blast_Score=253, Evalue=5e-69,
Organism=Escherichia coli, GI1787517, Length=199, Percent_Identity=39.6984924623116, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786215, Length=156, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788854, Length=191, Percent_Identity=26.7015706806283, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=49.1891891891892, Blast_Score=200, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=31.1004784688995, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323873, Length=142, Percent_Identity=28.8732394366197, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281365319, Length=139, Percent_Identity=30.2158273381295, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21963; Mature: 21963

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFTFNLVQFLGELGQDLVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHCCHHEEECCCCEEEEHHHCCCCCEEEECCCCCCCCCCC
ISMEVIRYFAGKIPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSLMHHDEKTIFSDIPN
CHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHHHCHHHHHHCCHHHHHHCCCC
PFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTLPIEGVQFHPESIMTSHGKEL
CCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LQNFIRKYSPSVTSC
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MILMIDNYDSFTFNLVQFLGELGQDLVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHCCHHEEECCCCEEEEHHHCCCCCEEEECCCCCCCCCCC
ISMEVIRYFAGKIPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSLMHHDEKTIFSDIPN
CHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHHHCHHHHHHCCHHHHHHCCCC
PFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTLPIEGVQFHPESIMTSHGKEL
CCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LQNFIRKYSPSVTSC
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]