| Definition | Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence. |
|---|---|
| Accession | NC_011961 |
| Length | 917,738 |
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The map label for this gene is 221636221
Identifier: 221636221
GI number: 221636221
Start: 801670
End: 802791
Strand: Reverse
Name: 221636221
Synonym: trd_A0815
Alternate gene names: NA
Gene position: 802791-801670 (Counterclockwise)
Preceding gene: 221636223
Following gene: 221636220
Centisome position: 87.47
GC content: 65.33
Gene sequence:
>1122_bases GTGGGAAGCGCCGAACGACCGGACGAGGAGCGTTCCGCTGATCGCTCGTCCGAGACGGGAAGAGAGCAGAGCGGGTGGAC TGCCCCAGCTGTGGCAGCAATCGCTCTCGAGAGCGACAGGGAGCTGACGAAGAAGTGTCTCGGGCAGACCGATCACGGTG CTAGGATTGACGCGACCGAGCCAGGGCACGTGGCTGGACGAGGAGCGGAGGAGATGGAACGACTCTGGGCGCCGTGGCGA CTGCGCTATGTGGAGGGAGAGATACGCCATCGGGGTTGCATCTTCTGCGAGAAGCCGGCGCTCGGTGACGATGTCGGAGA ACTGATCCTGCTGCGCGGGCGGCGGGCGTACCTGATCATGAACCTCTTCCCCTACAACACGGGACACGCGATGGCGGTAC CCTTCGACCACGTGGCGGACTTGGCCGAACTCGATCCGGCGACGATCGCTGAGCTTTTCGAACTGGTGGCATGGCTCACG ACAGCGCAGCGCCGGGCCTTACGGTGCGATGGTTTCAACATCGGCCTCAACCTCGGTGCGGTCGCGGGGGCGGGGATCAG CGACCATGTGCATGTGCACGTGGTGCCGCGTTGGCAGGGGGATGCCAACTTCATGCCCATCCTGGCGAACACGATGGTGA TTCCTGAGCTGATTCCCGTGACCTACGCCAAGTTGCGGGCGGAGTTGGAGCTTTCGGCGTTCGGTCGTGCGGACGACCTG GTGGTTCCGCAAGCGGGTGCCGTGGTGTGGCTGCCCGAGGAAAGGAAGCTCGCGATCCGGCGTGCTCGTGATGGGACACT GGTACTCCCGAAAGGGCACATCGAGCCGGGCGAGGCGGCCTACCGTGCTGCCTTGCGCGAGGTGGCCGAGGAGATGGGTT TGATCGCCGAGCTGATCGGCTGGGCAGGGGCGCTCGAGTTCGAGGCGGGCGGCAAGCGGCGGCGTGTCGTTTACATGCTC GTCCAGGCGAAGCCCGGGCCAGCATTCGCGCAGCACCTGGGGCGGGATACCGTGCTCATGGACGTGGAGGAGGCGCTGGC AGCGCTCAGTCACGAGGAAGTACGCGAGTTGGTCGCGACGACGATGCGTCGCATCGGGGTTCCTGTCGGAACGAGCCGAT GA
Upstream 100 bases:
>100_bases CGTGCTGCCGGTAGTATAGCGGAGGACACACGGTACGGACGCACACCGATCCTGTCGAGAAGGATCGCGGCGACCGCATC GGGATCGATCGAGCAACACG
Downstream 100 bases:
>100_bases TGCTGTCCGGCATACGTCGCCTCGTCCTCGTGGGGATGGTGATTTTGGCCGCGGTGCCGTTCGGCTCGGCCGCCGCACCG CCGAGCGCGTGCTTGGCGGT
Product: histidine triad
Products: NA
Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]
Number of amino acids: Translated: 373; Mature: 372
Protein sequence:
>373_residues MGSAERPDEERSADRSSETGREQSGWTAPAVAAIALESDRELTKKCLGQTDHGARIDATEPGHVAGRGAEEMERLWAPWR LRYVEGEIRHRGCIFCEKPALGDDVGELILLRGRRAYLIMNLFPYNTGHAMAVPFDHVADLAELDPATIAELFELVAWLT TAQRRALRCDGFNIGLNLGAVAGAGISDHVHVHVVPRWQGDANFMPILANTMVIPELIPVTYAKLRAELELSAFGRADDL VVPQAGAVVWLPEERKLAIRRARDGTLVLPKGHIEPGEAAYRAALREVAEEMGLIAELIGWAGALEFEAGGKRRRVVYML VQAKPGPAFAQHLGRDTVLMDVEEALAALSHEEVRELVATTMRRIGVPVGTSR
Sequences:
>Translated_373_residues MGSAERPDEERSADRSSETGREQSGWTAPAVAAIALESDRELTKKCLGQTDHGARIDATEPGHVAGRGAEEMERLWAPWR LRYVEGEIRHRGCIFCEKPALGDDVGELILLRGRRAYLIMNLFPYNTGHAMAVPFDHVADLAELDPATIAELFELVAWLT TAQRRALRCDGFNIGLNLGAVAGAGISDHVHVHVVPRWQGDANFMPILANTMVIPELIPVTYAKLRAELELSAFGRADDL VVPQAGAVVWLPEERKLAIRRARDGTLVLPKGHIEPGEAAYRAALREVAEEMGLIAELIGWAGALEFEAGGKRRRVVYML VQAKPGPAFAQHLGRDTVLMDVEEALAALSHEEVRELVATTMRRIGVPVGTSR >Mature_372_residues GSAERPDEERSADRSSETGREQSGWTAPAVAAIALESDRELTKKCLGQTDHGARIDATEPGHVAGRGAEEMERLWAPWRL RYVEGEIRHRGCIFCEKPALGDDVGELILLRGRRAYLIMNLFPYNTGHAMAVPFDHVADLAELDPATIAELFELVAWLTT AQRRALRCDGFNIGLNLGAVAGAGISDHVHVHVVPRWQGDANFMPILANTMVIPELIPVTYAKLRAELELSAFGRADDLV VPQAGAVVWLPEERKLAIRRARDGTLVLPKGHIEPGEAAYRAALREVAEEMGLIAELIGWAGALEFEAGGKRRRVVYMLV QAKPGPAFAQHLGRDTVLMDVEEALAALSHEEVRELVATTMRRIGVPVGTSR
Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]
COG id: COG0537
COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HIT domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011146 - InterPro: IPR011151 - InterPro: IPR001310 [H]
Pfam domain/function: PF01230 HIT [H]
EC number: =2.7.7.53 [H]
Molecular weight: Translated: 40833; Mature: 40702
Theoretical pI: Translated: 5.64; Mature: 5.64
Prosite motif: PS00893 NUDIX ; PS51084 HIT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGSAERPDEERSADRSSETGREQSGWTAPAVAAIALESDRELTKKCLGQTDHGARIDATE CCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHCCCCCCCCEECCCC PGHVAGRGAEEMERLWAPWRLRYVEGEIRHRGCIFCEKPALGDDVGELILLRGRRAYLIM CCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHEECCCCEEEEE NLFPYNTGHAMAVPFDHVADLAELDPATIAELFELVAWLTTAQRRALRCDGFNIGLNLGA EEECCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCEEECEEECC VAGAGISDHVHVHVVPRWQGDANFMPILANTMVIPELIPVTYAKLRAELELSAFGRADDL EECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE VVPQAGAVVWLPEERKLAIRRARDGTLVLPKGHIEPGEAAYRAALREVAEEMGLIAELIG ECCCCCEEEECCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH WAGALEFEAGGKRRRVVYMLVQAKPGPAFAQHLGRDTVLMDVEEALAALSHEEVRELVAT HHCEEEECCCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEEHHHHHHHHCHHHHHHHHHH TMRRIGVPVGTSR HHHHHCCCCCCCC >Mature Secondary Structure GSAERPDEERSADRSSETGREQSGWTAPAVAAIALESDRELTKKCLGQTDHGARIDATE CCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHCCCCCCCCEECCCC PGHVAGRGAEEMERLWAPWRLRYVEGEIRHRGCIFCEKPALGDDVGELILLRGRRAYLIM CCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHEECCCCEEEEE NLFPYNTGHAMAVPFDHVADLAELDPATIAELFELVAWLTTAQRRALRCDGFNIGLNLGA EEECCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCEEECEEECC VAGAGISDHVHVHVVPRWQGDANFMPILANTMVIPELIPVTYAKLRAELELSAFGRADDL EECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE VVPQAGAVVWLPEERKLAIRRARDGTLVLPKGHIEPGEAAYRAALREVAEEMGLIAELIG ECCCCCEEEECCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH WAGALEFEAGGKRRRVVYMLVQAKPGPAFAQHLGRDTVLMDVEEALAALSHEEVRELVAT HHCEEEECCCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEEHHHHHHHHCHHHHHHHHHH TMRRIGVPVGTSR HHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12368430; 12218036 [H]