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The map label for this gene is cutS [H]

Identifier: 221636182

GI number: 221636182

Start: 758538

End: 759023

Strand: Reverse

Name: cutS [H]

Synonym: trd_A0776

Alternate gene names: 221636182

Gene position: 759023-758538 (Counterclockwise)

Preceding gene: 221636183

Following gene: 221636181

Centisome position: 82.71

GC content: 64.81

Gene sequence:

>486_bases
ATGCAGCGAGTTCCGATCACGCTGACCGTGAATGGGCGGTCGATTTCTGCCGAGGTCGAAGCGCGCATGACGCTCGCCGA
TTTCCTGCGCGAGCAGCTGGGGCTCACTGGCACCAAATTGGGATGCGAGCACGGGGTCTGTGGGAGCTGCACGGTGCTGT
GGGACGGTGCAGCGGTGCGCTCGTGCCTCGTGCTGGCCGCTCAAGCTGATGGGGCGAATCTGACGACGATCGAGGGGCTG
GCGACCGGGGAAGCGATGCACCCGGTGCAGCAAGCGTTCTGGGAGCATCATGGGTTGCAATGCGGGTTCTGCACGCCTGG
TATGGTGCTGACTGCCGTGGCGTTGCTCGAGGAGAACCCAGCCCCGAGCGAGGAGGAGATCCGGGAGGCTTTGAGCGGCA
ATCTCTGCCGGTGCACGGGATACCAGAACATCGTCCGGGCTGTCCGAGCGGCAGCGGAACAGATGCAAGCGGGCCGGGGA
TCATGA

Upstream 100 bases:

>100_bases
CAGCGACGTACCGGCGGCAGATCACGCCCGTGGTGGTGCGACGAGCGATCGAGGCTGCCGCCGCGCGGGCCGGGTTCTGA
GCGAGGGGAGGCGGGGCACG

Downstream 100 bases:

>100_bases
GAGGGGCGCAGCGATGACGCTTCAGATCTTGCCAAGGGGAAAGTGGGTCGGAGCTCGGGTCAAGCGGGTGGAGGATCCAC
GCTTTCTGACTGGCGAAGCA

Product: carbon monoxide dehydrogenase small chain (COdehydrogenase subunit S) (CO-DH S)

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MQRVPITLTVNGRSISAEVEARMTLADFLREQLGLTGTKLGCEHGVCGSCTVLWDGAAVRSCLVLAAQADGANLTTIEGL
ATGEAMHPVQQAFWEHHGLQCGFCTPGMVLTAVALLEENPAPSEEEIREALSGNLCRCTGYQNIVRAVRAAAEQMQAGRG
S

Sequences:

>Translated_161_residues
MQRVPITLTVNGRSISAEVEARMTLADFLREQLGLTGTKLGCEHGVCGSCTVLWDGAAVRSCLVLAAQADGANLTTIEGL
ATGEAMHPVQQAFWEHHGLQCGFCTPGMVLTAVALLEENPAPSEEEIREALSGNLCRCTGYQNIVRAVRAAAEQMQAGRG
S
>Mature_161_residues
MQRVPITLTVNGRSISAEVEARMTLADFLREQLGLTGTKLGCEHGVCGSCTVLWDGAAVRSCLVLAAQADGANLTTIEGL
ATGEAMHPVQQAFWEHHGLQCGFCTPGMVLTAVALLEENPAPSEEEIREALSGNLCRCTGYQNIVRAVRAAAEQMQAGRG
S

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=155, Percent_Identity=41.9354838709677, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=46.6666666666667, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=45.5621301775148, Blast_Score=157, Evalue=2e-40,
Organism=Escherichia coli, GI1789232, Length=152, Percent_Identity=46.0526315789474, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1789246, Length=107, Percent_Identity=33.6448598130841, Blast_Score=64, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=46.1038961038961, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=43.125, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=41.7721518987342, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17737937, Length=172, Percent_Identity=38.953488372093, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=37.6543209876543, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=37.6543209876543, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647199, Length=136, Percent_Identity=38.9705882352941, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=36.1290322580645, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=36.875, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17042; Mature: 17042

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVPITLTVNGRSISAEVEARMTLADFLREQLGLTGTKLGCEHGVCGSCTVLWDGAAVR
CCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHH
SCLVLAAQADGANLTTIEGLATGEAMHPVQQAFWEHHGLQCGFCTPGMVLTAVALLEENP
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCC
APSEEEIREALSGNLCRCTGYQNIVRAVRAAAEQMQAGRGS
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQRVPITLTVNGRSISAEVEARMTLADFLREQLGLTGTKLGCEHGVCGSCTVLWDGAAVR
CCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHH
SCLVLAAQADGANLTTIEGLATGEAMHPVQQAFWEHHGLQCGFCTPGMVLTAVALLEENP
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCC
APSEEEIREALSGNLCRCTGYQNIVRAVRAAAEQMQAGRGS
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]