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The map label for this gene is cutM [H]

Identifier: 221636183

GI number: 221636183

Start: 759044

End: 759922

Strand: Reverse

Name: cutM [H]

Synonym: trd_A0777

Alternate gene names: 221636183

Gene position: 759922-759044 (Counterclockwise)

Preceding gene: 221636185

Following gene: 221636182

Centisome position: 82.8

GC content: 70.19

Gene sequence:

>879_bases
GTGGCGATGAAACCGGCAGCTTTTGCCTACGAGCGGCCGGGGACCCTCGGTGAGGCGCTCGAGGCGCTGGCGCGGCATGG
TTCGGATGCCCGGCCACTCGCTGGTGGGCAGAGCCTGGTGCCGATGCTGAGCTTGCGGCTGGCGCGTCCAGCGCTCTTGG
TCGACCTCGGTCGTCTCGCCGGGCTCGACGAGTTGGTCGTGCGGAATGGTGCGGTCGAGATCGGCGCGATGGTGCGGCAA
CGACGGTTGGAGCGTGATCCGCTGGTCGCCCAGCACGTGCCGGTGCTCGCTGCTGCGACACGGTACGTGGGGCATCCCTC
GATCCGGAATCGGGGTACGTTGGGCGGGAGCCTGGCTCATGCCGATCCGTCGGCTGAATACCCGGCGGTCGCGCTGGCAG
TGGATGCGGAGATGGTCGTCCGCAGCGCACGAGGCGAGCGGACGATCCCGGCACGTGACTTCTTCCTGGGACCCTTCACG
ACCGCCCTGGCTGAGGGCGAACTGCTCGTCGCGATCCGTTTTCCCGCATTACCGGCTGGCGCGGGTTGGGGTGTCGAGGA
GATCGCGCGGCGGCACGGCGACTTCGCGCTCGCTGGAGCAGTCGCGGTGCTGGAGCGTGGGCCGGACGGAACGTGCAGTC
GGGCGAGCGTGGCGCTCTTCGGTGTGGCGACGCGACCGTTGCGGGCGACCGCGGTCGAGCAGGCGCTCGTCGGGCGAGCC
CTGGACAGCGCGACGCTGCGTGAAGCAGCCGCTCTTGCGGCGGATGCGATCGACGAGCCGCTTTCCGATGTGCATGGGTC
AGCGACGTACCGGCGGCAGATCACGCCCGTGGTGGTGCGACGAGCGATCGAGGCTGCCGCCGCGCGGGCCGGGTTCTGA

Upstream 100 bases:

>100_bases
GCTGTCATCGTCGCGGATCCGGAAAGAAGCGTGCTATCTCGGGCTCGTCGGGTTAAGGAGCGGGTCGGGTGTTGTGTTTT
TCGGTGGATGAGTGGGGAGG

Downstream 100 bases:

>100_bases
GCGAGGGGAGGCGGGGCACGATGCAGCGAGTTCCGATCACGCTGACCGTGAATGGGCGGTCGATTTCTGCCGAGGTCGAA
GCGCGCATGACGCTCGCCGA

Product: carbon monoxide dehydrogenase medium chain (COdehydrogenase subunit M) (CO-DH M)

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAMKPAAFAYERPGTLGEALEALARHGSDARPLAGGQSLVPMLSLRLARPALLVDLGRLAGLDELVVRNGAVEIGAMVRQ
RRLERDPLVAQHVPVLAAATRYVGHPSIRNRGTLGGSLAHADPSAEYPAVALAVDAEMVVRSARGERTIPARDFFLGPFT
TALAEGELLVAIRFPALPAGAGWGVEEIARRHGDFALAGAVAVLERGPDGTCSRASVALFGVATRPLRATAVEQALVGRA
LDSATLREAAALAADAIDEPLSDVHGSATYRRQITPVVVRRAIEAAAARAGF

Sequences:

>Translated_292_residues
MAMKPAAFAYERPGTLGEALEALARHGSDARPLAGGQSLVPMLSLRLARPALLVDLGRLAGLDELVVRNGAVEIGAMVRQ
RRLERDPLVAQHVPVLAAATRYVGHPSIRNRGTLGGSLAHADPSAEYPAVALAVDAEMVVRSARGERTIPARDFFLGPFT
TALAEGELLVAIRFPALPAGAGWGVEEIARRHGDFALAGAVAVLERGPDGTCSRASVALFGVATRPLRATAVEQALVGRA
LDSATLREAAALAADAIDEPLSDVHGSATYRRQITPVVVRRAIEAAAARAGF
>Mature_291_residues
AMKPAAFAYERPGTLGEALEALARHGSDARPLAGGQSLVPMLSLRLARPALLVDLGRLAGLDELVVRNGAVEIGAMVRQR
RLERDPLVAQHVPVLAAATRYVGHPSIRNRGTLGGSLAHADPSAEYPAVALAVDAEMVVRSARGERTIPARDFFLGPFTT
ALAEGELLVAIRFPALPAGAGWGVEEIARRHGDFALAGAVAVLERGPDGTCSRASVALFGVATRPLRATAVEQALVGRAL
DSATLREAAALAADAIDEPLSDVHGSATYRRQITPVVVRRAIEAAAARAGF

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=289, Percent_Identity=31.1418685121107, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789245, Length=273, Percent_Identity=32.967032967033, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 30502; Mature: 30371

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMKPAAFAYERPGTLGEALEALARHGSDARPLAGGQSLVPMLSLRLARPALLVDLGRLA
CCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHC
GLDELVVRNGAVEIGAMVRQRRLERDPLVAQHVPVLAAATRYVGHPSIRNRGTLGGSLAH
CHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ADPSAEYPAVALAVDAEMVVRSARGERTIPARDFFLGPFTTALAEGELLVAIRFPALPAG
CCCCCCCCEEEEEECHHHHHHHHCCCCCCCHHHHCCCHHHHHHCCCCEEEEEECCCCCCC
AGWGVEEIARRHGDFALAGAVAVLERGPDGTCSRASVALFGVATRPLRATAVEQALVGRA
CCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHHHH
LDSATLREAAALAADAIDEPLSDVHGSATYRRQITPVVVRRAIEAAAARAGF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AMKPAAFAYERPGTLGEALEALARHGSDARPLAGGQSLVPMLSLRLARPALLVDLGRLA
CCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHC
GLDELVVRNGAVEIGAMVRQRRLERDPLVAQHVPVLAAATRYVGHPSIRNRGTLGGSLAH
CHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ADPSAEYPAVALAVDAEMVVRSARGERTIPARDFFLGPFTTALAEGELLVAIRFPALPAG
CCCCCCCCEEEEEECHHHHHHHHCCCCCCCHHHHCCCHHHHHHCCCCEEEEEECCCCCCC
AGWGVEEIARRHGDFALAGAVAVLERGPDGTCSRASVALFGVATRPLRATAVEQALVGRA
CCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHHHH
LDSATLREAAALAADAIDEPLSDVHGSATYRRQITPVVVRRAIEAAAARAGF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]