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The map label for this gene is soxA [H]

Identifier: 221636146

GI number: 221636146

Start: 729146

End: 730291

Strand: Reverse

Name: soxA [H]

Synonym: trd_A0740

Alternate gene names: 221636146

Gene position: 730291-729146 (Counterclockwise)

Preceding gene: 221636147

Following gene: 221636143

Centisome position: 79.58

GC content: 66.75

Gene sequence:

>1146_bases
ATGCGCAGCTCAGAGGTGATCGTGATCGGTCTCGGCGCGATGGGCGCCGCGACGGCGTGGGCGCTTGCACGCAGTGGCTT
CCGCGTACTCGGGCTGGACGCCTTCCGCCGCGGGCACGATCGCGGTTCGTCGCACGGCAAGACGCGGATCATCCGGACAG
CTTACTACGAGTCGCCGGAGTACGTCCCGTTGGTCCGGCGGGCGTGGACGCTCTGGCGGCAACTGGAGGCCGAGAGCGGC
CAGTCGCTCCTCCGGATGACGGGAGGGCTCTACGTGGGGCGACCGGACAGCTCGCTCGTGAGCGGGGTGCTGGCGAGCGT
TCGTGCGCATGGACTCGCGCATGAACTGCTGGAGGCCAGCGAGGCGATGGCGCGTTTTCCAGGGTTGCGGTTAGCACCCG
AACAGGTGGCTGTGTTCGAGCCGGAGGCTGGGTTGATCGACCCGGAGGCAGCGGTGGCAGCCATGCTCGACCGCGCCACG
GCCGCGGGAGCACAACTCCGGCATGAGACGCCAGTGATCGCCTGGGCGGTCGATGGTGACGGCGTCCGCGTGGAAACGCC
GGCTGGAACCTTTCGGGCGGATCGGTTGGTGCTGGCGGCGGGAGCGTGGTTGAGTCAGCTCGTCCCAGAGCTCGGATTAC
CACTCGAGGTGTGGCGTATCCTGCACGTGCACTTCGCACCCCGGGCCGGGGGACGCTACGCGGCGGATCGTTTTCCCTTC
GCCCTCTGGGAGGACGAAACAGGGCTCTACAGCGCGTTTCCGGAACTGCCGGGACAAGGGGTGAAGTTCGGCCGGCACGA
TACGGGAGAAGTCTGCACACCGCAAACGGTCCGACGTACGGCGACGAGCGAGGAAATCGCCGAACTGCGCCACGCACTGG
AACGGTACTGGCCCGAAGCTGGGGGAGCGGTGCTGTGGTATCTCACCTGCCTCTACACGGTCACACCCGATCATCATTTT
CTCATCGATCGGCACCCCCTTCGGCCACAGGTCGTTCTCTGCAGCGCGTGTTCCGGGCATGGTTTCAAGTTCGCTCCCGC
GATCGGCGAACTCGTCGCCGCACTGGCGATCGATTCCGGAGCGCAGCCAGCGGCACTCTTCCGCCTGGAGCGGTTTCGGC
GCGAGTCGATCGAAGCGGCACAGTGA

Upstream 100 bases:

>100_bases
GGCGATCAGGCTGGCCGCAGAGAAGACTCGCGCGGGGCAAAGGACGTGTCGTGAAAGCACTGAGAGCGCAAGGGCGTCGA
AACGAACGCGAGGAGGGCCG

Downstream 100 bases:

>100_bases
GCGTGGTGACGCCGGTCAGCTGGGAGTGGGTCGGATCCCCATTTCGTCGAGGGCGCGTGTCACCGATTGCTCGGTGACGG
GACCGACCCAGGCTTTGCGG

Product: monomeric sarcosine oxidase (msox)

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRSSEVIVIGLGAMGAATAWALARSGFRVLGLDAFRRGHDRGSSHGKTRIIRTAYYESPEYVPLVRRAWTLWRQLEAESG
QSLLRMTGGLYVGRPDSSLVSGVLASVRAHGLAHELLEASEAMARFPGLRLAPEQVAVFEPEAGLIDPEAAVAAMLDRAT
AAGAQLRHETPVIAWAVDGDGVRVETPAGTFRADRLVLAAGAWLSQLVPELGLPLEVWRILHVHFAPRAGGRYAADRFPF
ALWEDETGLYSAFPELPGQGVKFGRHDTGEVCTPQTVRRTATSEEIAELRHALERYWPEAGGAVLWYLTCLYTVTPDHHF
LIDRHPLRPQVVLCSACSGHGFKFAPAIGELVAALAIDSGAQPAALFRLERFRRESIEAAQ

Sequences:

>Translated_381_residues
MRSSEVIVIGLGAMGAATAWALARSGFRVLGLDAFRRGHDRGSSHGKTRIIRTAYYESPEYVPLVRRAWTLWRQLEAESG
QSLLRMTGGLYVGRPDSSLVSGVLASVRAHGLAHELLEASEAMARFPGLRLAPEQVAVFEPEAGLIDPEAAVAAMLDRAT
AAGAQLRHETPVIAWAVDGDGVRVETPAGTFRADRLVLAAGAWLSQLVPELGLPLEVWRILHVHFAPRAGGRYAADRFPF
ALWEDETGLYSAFPELPGQGVKFGRHDTGEVCTPQTVRRTATSEEIAELRHALERYWPEAGGAVLWYLTCLYTVTPDHHF
LIDRHPLRPQVVLCSACSGHGFKFAPAIGELVAALAIDSGAQPAALFRLERFRRESIEAAQ
>Mature_381_residues
MRSSEVIVIGLGAMGAATAWALARSGFRVLGLDAFRRGHDRGSSHGKTRIIRTAYYESPEYVPLVRRAWTLWRQLEAESG
QSLLRMTGGLYVGRPDSSLVSGVLASVRAHGLAHELLEASEAMARFPGLRLAPEQVAVFEPEAGLIDPEAAVAAMLDRAT
AAGAQLRHETPVIAWAVDGDGVRVETPAGTFRADRLVLAAGAWLSQLVPELGLPLEVWRILHVHFAPRAGGRYAADRFPF
ALWEDETGLYSAFPELPGQGVKFGRHDTGEVCTPQTVRRTATSEEIAELRHALERYWPEAGGAVLWYLTCLYTVTPDHHF
LIDRHPLRPQVVLCSACSGHGFKFAPAIGELVAALAIDSGAQPAALFRLERFRRESIEAAQ

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=380, Percent_Identity=33.1578947368421, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI24797151, Length=276, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787298, Length=379, Percent_Identity=34.3007915567282, Blast_Score=194, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI115535191, Length=382, Percent_Identity=26.7015706806283, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25147318, Length=384, Percent_Identity=26.3020833333333, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41541; Mature: 41541

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSEVIVIGLGAMGAATAWALARSGFRVLGLDAFRRGHDRGSSHGKTRIIRTAYYESPE
CCCCCEEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCEEEEEEEECCCCC
YVPLVRRAWTLWRQLEAESGQSLLRMTGGLYVGRPDSSLVSGVLASVRAHGLAHELLEAS
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EAMARFPGLRLAPEQVAVFEPEAGLIDPEAAVAAMLDRATAAGAQLRHETPVIAWAVDGD
HHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCC
GVRVETPAGTFRADRLVLAAGAWLSQLVPELGLPLEVWRILHVHFAPRAGGRYAADRFPF
CEEEECCCCCCHHHHEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
ALWEDETGLYSAFPELPGQGVKFGRHDTGEVCTPQTVRRTATSEEIAELRHALERYWPEA
EEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCC
GGAVLWYLTCLYTVTPDHHFLIDRHPLRPQVVLCSACSGHGFKFAPAIGELVAALAIDSG
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHCCC
AQPAALFRLERFRRESIEAAQ
CCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSSEVIVIGLGAMGAATAWALARSGFRVLGLDAFRRGHDRGSSHGKTRIIRTAYYESPE
CCCCCEEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCEEEEEEEECCCCC
YVPLVRRAWTLWRQLEAESGQSLLRMTGGLYVGRPDSSLVSGVLASVRAHGLAHELLEAS
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EAMARFPGLRLAPEQVAVFEPEAGLIDPEAAVAAMLDRATAAGAQLRHETPVIAWAVDGD
HHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCC
GVRVETPAGTFRADRLVLAAGAWLSQLVPELGLPLEVWRILHVHFAPRAGGRYAADRFPF
CEEEECCCCCCHHHHEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
ALWEDETGLYSAFPELPGQGVKFGRHDTGEVCTPQTVRRTATSEEIAELRHALERYWPEA
EEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCC
GGAVLWYLTCLYTVTPDHHFLIDRHPLRPQVVLCSACSGHGFKFAPAIGELVAALAIDSG
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHCCC
AQPAALFRLERFRRESIEAAQ
CCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]