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The map label for this gene is 221636098

Identifier: 221636098

GI number: 221636098

Start: 680371

End: 682428

Strand: Reverse

Name: 221636098

Synonym: trd_A0692

Alternate gene names: NA

Gene position: 682428-680371 (Counterclockwise)

Preceding gene: 221636099

Following gene: 221636097

Centisome position: 74.36

GC content: 68.8

Gene sequence:

>2058_bases
GTGCTGATGCGGTGGACGCCGATCCGGTCCCGGCTGCTCGCCTGGCTCCTGATCCCGGTTCTGCTCCTGGGCGGGTCGCC
GCGCTCGCTGGACGGGGCGCAGGCGCACGAGACGACACTTGCGGAGGCGGTGGAATGGGCGGTGGCGGTCGAACGCGCAA
CCTGCTCTATCGCTCGTCAGCCTCACCCGGAGCCTCTCTGCCTAGCTGATCTCCCCGCTCGACTGGAACCGATCGATCCG
GATGGGCAGTGGTGGCGGCTCCGCTTCGATCAGCCGGCGACTGCTGCCGATTGGATCGTGCGTCTGATGGGACGGCCGGG
AGTCACTGGGCTGGAGCCGGCGGTGCGCCTGTTCTACCAGTGGACACCAGCCGATCCGCTGGTCGCCCAGCAAGAGTGGT
TGACGGTGGCCGGCTTTCCGACGGCCTGGGACGACACGATCGGCCGGGCGGAGGTGTCTGTCGCGGTGATCGATTCCGGG
GTGGCAGCGCGTCATCCGGATCTGGCAGGAAAGCTGCTGCCGGGATACGACTACCTACGACGCGATCCTGATCCGGACGA
CGAGGTCGGGCATGGGACGGCGGTGGCGGGAGTCATCGCGGCTGCGGCTGATGGGCGCGGAATGGTGGGCGGTGCACCGG
GTGTCAAGATCGTGCCGCTCAAGGTCGGCGATCAGATCGGTGCGAGTTCGCTCTTGATCGCGGAAGCGGTCTACGGAGCG
ATCGAGCGCGGCGTGCAGGTGATCAACTTGAGCCTGGGGGCGGATACGCCGAGCGGTGCGCTGGAACGCGCGATCGAGCA
AGCGTACGCGCGAGGCATCGTGGTCGTCGCGGCGGCAGGCAACACGCCCGACAGTGTGACCTTCCCGGCCAGTTATCCTG
AGGTGGTCGCGGTGGGCGGTGCGACGGCCGATGGCAAGCGCTTGGCCAGCTTTACCTCGCGGCTAACGCGGGTCGACCTG
GTCGCACCAGCCGAGAACGTGCTGACGACGAGCTGGGACGGGCAAGAGCCCGGATGGGACCGGCGGACGGGTACCTCCTT
CGCGGCGCCGATGGTGAGCGCGGCAGCAGCGCTGGTTCGTTCCATCGCGCCGGACAGCAGCGTGGAGTGGGTGCGGCAGA
CTCTGCGCGAGACGGCGTCCCCGCTGGATCCGCCGGGCCAGCCAGGGGCTGGCAGCGGACTCCTCTCGGCCAGGGGTGCG
GTCGAGCGCGCAGTGCTGCGGCGCTTCGCCCAGACGTGGCAGCGGGCTGATCTCCCGGTGGCAGCCGGACAGGCGACCCG
CTCGTGGGTGTGGGGCCCCAGCGCCTTCGCGGTCGGCCGCGAGCCGTATGCGGAGACGCGCGCCGGAACGCGCGCGGTGG
CCTATTTCGACAAGGCGCGCCTGGAACTCACCGACCCCGATCGTTCTCCCGAGGATCCGTGGGCAGTGACCTCGGGGTTG
CTCGCCCGCGAACTGATCAGCGGCATGGAACAAGTGGGAGACAGGCGGTTCGTCCCACGTTCGCCAGCCAGCATCCCGGT
CGCTGGTGATCCGGACGATCGGCTCGGTCCGACATACGCGACGCTCGCTGCCGTGCTGGCTCTGCCACCGCTCGAAGAAG
GAGAGCTGATCACGCAGACGATCGATCGGAGCGGCCGAGTCGGGAACGAGCAGCGTCTCGCTGGCTACGGCGTACGGGCC
GGACCGCTCGTGCCGGAAACAGGCCATCGCGTCGCTTCGGTCTTCTGGGAGTTCTTGCAGGGGCGGGATGTCGTCTATAC
CGGCGGCCGTTTCGAGACGGCTGACCTGTTTTGGCCGCCGTTTGCGATCACCGGCTTCCCGATCACGGAAGCGTACTGGG
CACGGGTCACGGTGGGCGGAGTGGTACGGGACGTGCTGGTCCAGTGCTTCGAGCGTCGTTGCCTGACGTATACGCCGGAG
AACCTTCCTGGCTGGCGCGTGGAGCTCGGCAACGTGGGGCAGCACTACTACCGCTGGCGGTACGGCGCACTACCGGACCA
GCCGCCAGCCAGTGACCCTGCGGCGATGGCCCCGGTGGACGGTAGCGGACGCGGCTGA

Upstream 100 bases:

>100_bases
ACCGGGGATTCATCGTACCTGGTTTGGGCGATGCTGGAGACCGGCTGTTCGGGACGCAGTGAGCGGCCGAGCGCGTCGAG
GCAACAGCGGTTGAGCGGTG

Downstream 100 bases:

>100_bases
AGCGGCGTAGACTGTCCCCTGGCCGACCTGGCAGAGAGTCTGTCGGGTCGGCGGAGGGGAGTACGGGGACAGTGCGACCA
GGCGCGAAGGCGCCAGTAGC

Product: peptidase families S8 and S53 domain protein

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MLMRWTPIRSRLLAWLLIPVLLLGGSPRSLDGAQAHETTLAEAVEWAVAVERATCSIARQPHPEPLCLADLPARLEPIDP
DGQWWRLRFDQPATAADWIVRLMGRPGVTGLEPAVRLFYQWTPADPLVAQQEWLTVAGFPTAWDDTIGRAEVSVAVIDSG
VAARHPDLAGKLLPGYDYLRRDPDPDDEVGHGTAVAGVIAAAADGRGMVGGAPGVKIVPLKVGDQIGASSLLIAEAVYGA
IERGVQVINLSLGADTPSGALERAIEQAYARGIVVVAAAGNTPDSVTFPASYPEVVAVGGATADGKRLASFTSRLTRVDL
VAPAENVLTTSWDGQEPGWDRRTGTSFAAPMVSAAAALVRSIAPDSSVEWVRQTLRETASPLDPPGQPGAGSGLLSARGA
VERAVLRRFAQTWQRADLPVAAGQATRSWVWGPSAFAVGREPYAETRAGTRAVAYFDKARLELTDPDRSPEDPWAVTSGL
LARELISGMEQVGDRRFVPRSPASIPVAGDPDDRLGPTYATLAAVLALPPLEEGELITQTIDRSGRVGNEQRLAGYGVRA
GPLVPETGHRVASVFWEFLQGRDVVYTGGRFETADLFWPPFAITGFPITEAYWARVTVGGVVRDVLVQCFERRCLTYTPE
NLPGWRVELGNVGQHYYRWRYGALPDQPPASDPAAMAPVDGSGRG

Sequences:

>Translated_685_residues
MLMRWTPIRSRLLAWLLIPVLLLGGSPRSLDGAQAHETTLAEAVEWAVAVERATCSIARQPHPEPLCLADLPARLEPIDP
DGQWWRLRFDQPATAADWIVRLMGRPGVTGLEPAVRLFYQWTPADPLVAQQEWLTVAGFPTAWDDTIGRAEVSVAVIDSG
VAARHPDLAGKLLPGYDYLRRDPDPDDEVGHGTAVAGVIAAAADGRGMVGGAPGVKIVPLKVGDQIGASSLLIAEAVYGA
IERGVQVINLSLGADTPSGALERAIEQAYARGIVVVAAAGNTPDSVTFPASYPEVVAVGGATADGKRLASFTSRLTRVDL
VAPAENVLTTSWDGQEPGWDRRTGTSFAAPMVSAAAALVRSIAPDSSVEWVRQTLRETASPLDPPGQPGAGSGLLSARGA
VERAVLRRFAQTWQRADLPVAAGQATRSWVWGPSAFAVGREPYAETRAGTRAVAYFDKARLELTDPDRSPEDPWAVTSGL
LARELISGMEQVGDRRFVPRSPASIPVAGDPDDRLGPTYATLAAVLALPPLEEGELITQTIDRSGRVGNEQRLAGYGVRA
GPLVPETGHRVASVFWEFLQGRDVVYTGGRFETADLFWPPFAITGFPITEAYWARVTVGGVVRDVLVQCFERRCLTYTPE
NLPGWRVELGNVGQHYYRWRYGALPDQPPASDPAAMAPVDGSGRG
>Mature_685_residues
MLMRWTPIRSRLLAWLLIPVLLLGGSPRSLDGAQAHETTLAEAVEWAVAVERATCSIARQPHPEPLCLADLPARLEPIDP
DGQWWRLRFDQPATAADWIVRLMGRPGVTGLEPAVRLFYQWTPADPLVAQQEWLTVAGFPTAWDDTIGRAEVSVAVIDSG
VAARHPDLAGKLLPGYDYLRRDPDPDDEVGHGTAVAGVIAAAADGRGMVGGAPGVKIVPLKVGDQIGASSLLIAEAVYGA
IERGVQVINLSLGADTPSGALERAIEQAYARGIVVVAAAGNTPDSVTFPASYPEVVAVGGATADGKRLASFTSRLTRVDL
VAPAENVLTTSWDGQEPGWDRRTGTSFAAPMVSAAAALVRSIAPDSSVEWVRQTLRETASPLDPPGQPGAGSGLLSARGA
VERAVLRRFAQTWQRADLPVAAGQATRSWVWGPSAFAVGREPYAETRAGTRAVAYFDKARLELTDPDRSPEDPWAVTSGL
LARELISGMEQVGDRRFVPRSPASIPVAGDPDDRLGPTYATLAAVLALPPLEEGELITQTIDRSGRVGNEQRLAGYGVRA
GPLVPETGHRVASVFWEFLQGRDVVYTGGRFETADLFWPPFAITGFPITEAYWARVTVGGVVRDVLVQCFERRCLTYTPE
NLPGWRVELGNVGQHYYRWRYGALPDQPPASDPAAMAPVDGSGRG

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=261, Percent_Identity=30.6513409961686, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324576, Length=272, Percent_Identity=27.5735294117647, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319893, Length=238, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550681, Length=291, Percent_Identity=29.553264604811, Blast_Score=81, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 73331; Mature: 73331

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMRWTPIRSRLLAWLLIPVLLLGGSPRSLDGAQAHETTLAEAVEWAVAVERATCSIARQ
CCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHPEPLCLADLPARLEPIDPDGQWWRLRFDQPATAADWIVRLMGRPGVTGLEPAVRLFYQ
CCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHEEEEE
WTPADPLVAQQEWLTVAGFPTAWDDTIGRAEVSVAVIDSGVAARHPDLAGKLLPGYDYLR
ECCCCCCCCHHCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHH
RDPDPDDEVGHGTAVAGVIAAAADGRGMVGGAPGVKIVPLKVGDQIGASSLLIAEAVYGA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
IERGVQVINLSLGADTPSGALERAIEQAYARGIVVVAAAGNTPDSVTFPASYPEVVAVGG
HHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEECCCCCCCEEEECC
ATADGKRLASFTSRLTRVDLVAPAENVLTTSWDGQEPGWDRRTGTSFAAPMVSAAAALVR
CCCCHHHHHHHHHHHHHEEEECCCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SIAPDSSVEWVRQTLRETASPLDPPGQPGAGSGLLSARGAVERAVLRRFAQTWQRADLPV
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
AAGQATRSWVWGPSAFAVGREPYAETRAGTRAVAYFDKARLELTDPDRSPEDPWAVTSGL
ECCCCCCCEECCCCHHCCCCCCCHHHHCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHH
LARELISGMEQVGDRRFVPRSPASIPVAGDPDDRLGPTYATLAAVLALPPLEEGELITQT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
IDRSGRVGNEQRLAGYGVRAGPLVPETGHRVASVFWEFLQGRDVVYTGGRFETADLFWPP
HHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEECCEECCC
FAITGFPITEAYWARVTVGGVVRDVLVQCFERRCLTYTPENLPGWRVELGNVGQHYYRWR
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHEE
YGALPDQPPASDPAAMAPVDGSGRG
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLMRWTPIRSRLLAWLLIPVLLLGGSPRSLDGAQAHETTLAEAVEWAVAVERATCSIARQ
CCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHPEPLCLADLPARLEPIDPDGQWWRLRFDQPATAADWIVRLMGRPGVTGLEPAVRLFYQ
CCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHEEEEE
WTPADPLVAQQEWLTVAGFPTAWDDTIGRAEVSVAVIDSGVAARHPDLAGKLLPGYDYLR
ECCCCCCCCHHCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHH
RDPDPDDEVGHGTAVAGVIAAAADGRGMVGGAPGVKIVPLKVGDQIGASSLLIAEAVYGA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
IERGVQVINLSLGADTPSGALERAIEQAYARGIVVVAAAGNTPDSVTFPASYPEVVAVGG
HHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEECCCCCCCEEEECC
ATADGKRLASFTSRLTRVDLVAPAENVLTTSWDGQEPGWDRRTGTSFAAPMVSAAAALVR
CCCCHHHHHHHHHHHHHEEEECCCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SIAPDSSVEWVRQTLRETASPLDPPGQPGAGSGLLSARGAVERAVLRRFAQTWQRADLPV
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
AAGQATRSWVWGPSAFAVGREPYAETRAGTRAVAYFDKARLELTDPDRSPEDPWAVTSGL
ECCCCCCCEECCCCHHCCCCCCCHHHHCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHH
LARELISGMEQVGDRRFVPRSPASIPVAGDPDDRLGPTYATLAAVLALPPLEEGELITQT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
IDRSGRVGNEQRLAGYGVRAGPLVPETGHRVASVFWEFLQGRDVVYTGGRFETADLFWPP
HHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEECCEECCC
FAITGFPITEAYWARVTVGGVVRDVLVQCFERRCLTYTPENLPGWRVELGNVGQHYYRWR
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHEE
YGALPDQPPASDPAAMAPVDGSGRG
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]