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The map label for this gene is manA [H]

Identifier: 221635889

GI number: 221635889

Start: 471826

End: 472929

Strand: Reverse

Name: manA [H]

Synonym: trd_A0482

Alternate gene names: 221635889

Gene position: 472929-471826 (Counterclockwise)

Preceding gene: 221635890

Following gene: 221635887

Centisome position: 51.53

GC content: 67.84

Gene sequence:

>1104_bases
ATGAACGCGGCGCTCCTCGCCCGGCCCATGCTCCTCGAACCGGTCCTGGTCGAGCGCCCCTGGGGCGACCAGCGTCTGGC
GCGCTACCTCGGCAAATCGCTGCCGCATGGCGCGCGCATCGGCGAATCGTGGGAGACCGCGAACGAAGCCCGTGTCGCCA
GCGGCCCGCTGGCGGGACTGACGCTCCGCGAACTCGTCGCGCAATTCGGGGCAGATCTCTTGGGCCAGCGCGGCATGGCA
GCCAGTCAGCCGTTCGGCGACTTTCCCCTCCTGATCAAGCTGATCGATGCTGACGATGTGCTGTCCGTCCAAGTTCACCC
TGATGACGAGCAGGCCGCAGCGCTCGGGCAGCGCGGCAAGACGGAAGCATGGCACATCCTGGCAGCCGAACCCGGAGCCG
AACTGATCGTCGGACTGGCCGAGCTGCTCGATCCCCCGGCTCTCCGTCTCCACATCGCAACCGGCGAGCTGCCTCGGGTC
CTTGCGCACTTGCCAGTCCAGCCTGGGGACACGGTCGTCGTCCCAGCCGGAACCCTGCACGCCATCGGCCCCGGGATCCT
GCTGTACGAGATTCAAGAGCAGTCGGACATCACATACCGATTTTACGACTGGGGACGCGTCGATGCGCAAGGTCGAGGTC
GTCCCCTGCATATCGAGGAAGGGCTCGCTGTCCTCCGCCCGGAGCGCCGTGCTCAGCGGACGCAACCCCTTCCGCTCGAC
GACTGGCGTACCGTCTTGGCTGCCTGCCGATATTTCCTCCTGGAGCGCTGGACGATCGCTGGCAAACGTGTGTTCACGCG
CCAACCGGGCCAGACCCCCTCGATCCTCACCTGCCTGGAGGGCACACTGGCGATCCAGACCGACGGAGACGAACTCCACC
TGGTGCGCGGCGAGACTGCGCTAGTACCCGCGAGCGTCGCATCGCTCGCGGTGGCTGGTCAGGCGACCGTGCTGGCGGCC
AGCGTGCCCGACCTGCGCCAAGACATCGTCATCCCCCTCCGCGCCGCTGGCTACGACGAGGCCGCGATCGCCCAGCTCGC
CGGTGACACCGGCGACCTCGCGCACGCACTGGCAGCCAGCGAACCTGGTGAGCGCCGCTCATAG

Upstream 100 bases:

>100_bases
CGGTCCCGTTCCTCCAAGAAGTCTGGCGGCACCTGGCGTATGGCCTGACACTCGGCATCCTCTACGACCGCTGGCAGCGG
AAGGAGGGCGAGCCGGCACC

Downstream 100 bases:

>100_bases
CGCTCCCTCGCCAGCGAGCACCCCAGCACTTTCACCGGCGACCGACCGGCCAGGCTGACAACGCGAGTAGCCGGCGGACG
GAGCGACCAGCTCGCTCGGC

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNAALLARPMLLEPVLVERPWGDQRLARYLGKSLPHGARIGESWETANEARVASGPLAGLTLRELVAQFGADLLGQRGMA
ASQPFGDFPLLIKLIDADDVLSVQVHPDDEQAAALGQRGKTEAWHILAAEPGAELIVGLAELLDPPALRLHIATGELPRV
LAHLPVQPGDTVVVPAGTLHAIGPGILLYEIQEQSDITYRFYDWGRVDAQGRGRPLHIEEGLAVLRPERRAQRTQPLPLD
DWRTVLAACRYFLLERWTIAGKRVFTRQPGQTPSILTCLEGTLAIQTDGDELHLVRGETALVPASVASLAVAGQATVLAA
SVPDLRQDIVIPLRAAGYDEAAIAQLAGDTGDLAHALAASEPGERRS

Sequences:

>Translated_367_residues
MNAALLARPMLLEPVLVERPWGDQRLARYLGKSLPHGARIGESWETANEARVASGPLAGLTLRELVAQFGADLLGQRGMA
ASQPFGDFPLLIKLIDADDVLSVQVHPDDEQAAALGQRGKTEAWHILAAEPGAELIVGLAELLDPPALRLHIATGELPRV
LAHLPVQPGDTVVVPAGTLHAIGPGILLYEIQEQSDITYRFYDWGRVDAQGRGRPLHIEEGLAVLRPERRAQRTQPLPLD
DWRTVLAACRYFLLERWTIAGKRVFTRQPGQTPSILTCLEGTLAIQTDGDELHLVRGETALVPASVASLAVAGQATVLAA
SVPDLRQDIVIPLRAAGYDEAAIAQLAGDTGDLAHALAASEPGERRS
>Mature_367_residues
MNAALLARPMLLEPVLVERPWGDQRLARYLGKSLPHGARIGESWETANEARVASGPLAGLTLRELVAQFGADLLGQRGMA
ASQPFGDFPLLIKLIDADDVLSVQVHPDDEQAAALGQRGKTEAWHILAAEPGAELIVGLAELLDPPALRLHIATGELPRV
LAHLPVQPGDTVVVPAGTLHAIGPGILLYEIQEQSDITYRFYDWGRVDAQGRGRPLHIEEGLAVLRPERRAQRTQPLPLD
DWRTVLAACRYFLLERWTIAGKRVFTRQPGQTPSILTCLEGTLAIQTDGDELHLVRGETALVPASVASLAVAGQATVLAA
SVPDLRQDIVIPLRAAGYDEAAIAQLAGDTGDLAHALAASEPGERRS

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 39437; Mature: 39437

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAALLARPMLLEPVLVERPWGDQRLARYLGKSLPHGARIGESWETANEARVASGPLAGL
CCCHHHCCCHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCEECCCCCCCH
TLRELVAQFGADLLGQRGMAASQPFGDFPLLIKLIDADDVLSVQVHPDDEQAAALGQRGK
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHCCCCC
TEAWHILAAEPGAELIVGLAELLDPPALRLHIATGELPRVLAHLPVQPGDTVVVPAGTLH
CCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCHH
AIGPGILLYEIQEQSDITYRFYDWGRVDAQGRGRPLHIEEGLAVLRPERRAQRTQPLPLD
HCCCCEEEEEEECCCCCEEEEEECCEECCCCCCCEEEHHCCHHHCCCHHHHHCCCCCCCH
DWRTVLAACRYFLLERWTIAGKRVFTRQPGQTPSILTCLEGTLAIQTDGDELHLVRGETA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHEECCCEEEEEECCCEEEEEECCCE
LVPASVASLAVAGQATVLAASVPDLRQDIVIPLRAAGYDEAAIAQLAGDTGDLAHALAAS
ECCHHHHHHHHCCCEEEEEECCCHHHHCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHCC
EPGERRS
CCCCCCC
>Mature Secondary Structure
MNAALLARPMLLEPVLVERPWGDQRLARYLGKSLPHGARIGESWETANEARVASGPLAGL
CCCHHHCCCHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCEECCCCCCCH
TLRELVAQFGADLLGQRGMAASQPFGDFPLLIKLIDADDVLSVQVHPDDEQAAALGQRGK
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHCCCCC
TEAWHILAAEPGAELIVGLAELLDPPALRLHIATGELPRVLAHLPVQPGDTVVVPAGTLH
CCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCHH
AIGPGILLYEIQEQSDITYRFYDWGRVDAQGRGRPLHIEEGLAVLRPERRAQRTQPLPLD
HCCCCEEEEEEECCCCCEEEEEECCEECCCCCCCEEEHHCCHHHCCCHHHHHCCCCCCCH
DWRTVLAACRYFLLERWTIAGKRVFTRQPGQTPSILTCLEGTLAIQTDGDELHLVRGETA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHEECCCEEEEEECCCEEEEEECCCE
LVPASVASLAVAGQATVLAASVPDLRQDIVIPLRAAGYDEAAIAQLAGDTGDLAHALAAS
ECCHHHHHHHHCCCEEEEEECCCHHHHCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHCC
EPGERRS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]