Click here to switch to the map view.

The map label for this gene is cutL [H]

Identifier: 221635743

GI number: 221635743

Start: 324171

End: 326534

Strand: Reverse

Name: cutL [H]

Synonym: trd_A0337

Alternate gene names: 221635743

Gene position: 326534-324171 (Counterclockwise)

Preceding gene: 221635744

Following gene: 221635742

Centisome position: 35.58

GC content: 59.6

Gene sequence:

>2364_bases
ATGATCGGCCAGTCGGTCAAACGTGTCGAGGATTTTCGCTTTCTTACAGGCCAGGCCTGTTATACGAGAGACGTGCAGAT
TCCCGGGACTGCTCCGCTTCAGGCTCTTTTTCTCCGTAGCCCCTATCCTGCAGCGCGCATTACGCGCATCCTCACGGAGC
AGGCGGCCCGTGTACCCGGTGTTGTTGCCGTCCTCACCGCCGCAGCTCTTCCCGGTCATCTCCGGCCCATCCCCCTCATC
CGCAAACCACCAACGAGTCATCACGCCTTACCGGTCATCCCGCTTCTCGCTGATCAGGTCGTCCGGTATCAAGGTGAACC
TATCGCCTGCGTCGTTGCCACGACCGAAGCCGTCGCGCAGGACGCCTTGGAACTCATCCAGGTCGAGTACGAGCCACTCC
CAGCGGTTGGACAAATCGATGCGGCGATCGGCTCGGATGCACCGCTCGTGCATCCCGACTTGGAGACGAACATCGCCTTC
TCGGCGACCCTCCGGAACGGCCCAGTCGACGACGCCTTCGGCAAGGCCGCTGTGGTCGTCCGTCAGCGAATGCACAACAA
TCGAGTCGTGCCGCATCCGCTCGAACCGCGTAGCGTGCTTGCGTCCTATGATCGGGAAACCCGTCAACTGACAGTCTGGT
TTTCCACACAGCGCCCGCATCACACACGATGGTTTCTTTCCCAGATCCTCGACTATCCCGAGAACCTCATACGCGTCATC
ATGCCGGATGTCGGCGGTGCGTTCGGTTGCAAGGAACCGATCTATCCGGACGAAGTGCTCGTTTGTCTCGCGAGCATGCT
CCTCCAGCGCCCTGTCCGGTGGACCGAGAGTCGCAGCGAGCATTTCCTCTCCACGACCCACGGGCGCGACCAACTCGCGG
ATCTCGAACTCGCCGCGGATGCCGACGGCAGGCTACTCGGCCTGCGCGGTACGGTCTGGCTCAATATCGGTGCATACCTG
TATCCAAACACCTCTGGCGTGGTTCTCGCTCGCACCTTGCCCCTTCTCCCCGGTGCCTACGACATTCCCGCCTTCGATGT
CACGGCCCACGGCGTCTTCACCAATACCGTTCCCACAGGACCGTATCGTGGTGCGGGCCGCCCAGAAGCCATCTACTTCA
TCGAACGGCTCATCGATATCCTCGCGAGCAAACTGAATATCGACCCTGCAGAAATTCGGAGACGTAACTTCCTCGAGCTT
TCTCCCGAGAAACCCACTCGTACTATCACCGGGCTCAGCTACGACTCAGGCAACTTTCGTCAGATTCTCGACACTGCGCT
CGAGCTGAGTTCTTACCGTGAGCACCGACTCCGCCAACGGAACGGCGATTCAGAAGAGCGGCTGATCGGCATCGGAATCG
CTGCATACGTCGAATTAGGCGGTGCCACGCCTTCCACGGCAGCCGCCCTAGAAGGCTCTCCACCGCTGTGGGAGAGCGCG
ACGGTCACAGCTGACCCTACGGGGTCGATTGTGGTGCGTGTCGGTACAGCTGGACATGGGCAAGGGCATGAGACGACGTT
TGCGCAAATCGCTGCTTCCGTCCTCGGAATCCCGCTTTCATCGATCCGCGTCGAGTTCGGTGATACAGCAACTGCGCCCT
TCGGCTTCGGAACGTTCGGGACACGCTCGATGACGGTCGGTGGCTCGGCCGTCTATCTTGCCTGTCAGCAGCTCCTGCAA
CATGCCATCAAGCTCGCGGCCGAAATGCTCGAAGCGAACAGCTCGGATGTGGTCTACGATCGCGGCTACTTTTACGTCCG
CGGTCTAGAGGATCGGTCAGTCAGCTTCCAGGAGGTCTGCCACGCTGCCTATTTCTCTCTCGTCCCCTTCCGCGCAGGAC
TCCAACCCGGACTACAAGTCACTGCGACGTACGATCCGCCCAATTACACCTTTGCGACCGGTGTCCATGTGGCAGTGGTC
GCGATCGATCGACATACCGGGCAGCTCGATGTTCTGTCCTATGTCGGCGTCGATGACTGTGGTCGTGCCATCAACCCGAT
GATCGTCGAAGGACAACTGCACGGCGGCATCGCCCAAGGTATCGGCCAAGCCTTGTTCGAGCACGCACGATATTCTCGCG
ATGGTATTCTGATGAACCCCTCTTTATTGGACTACGCTCTTCCGCGGTCGACTCATCTCCCAACCTTCGAGACCCACCTC
ATCGAATTCCCTTCTCTCTCTAACCCTCTCGGAGTCAAGGGTATCGGCGAGGGAGGAGCCATCGTCGGACCGGTTGCGAT
CACCAACGCCGTCCACGATGCGCTTCGTTGCTTCGGGATCACTCATCTCAATATGCCACATACACCAGAGCAACTTTGGC
GAGTCATCGGGCGCGGTGAAGCAGGAGAAAGGAGAGAAGAGTGA

Upstream 100 bases:

>100_bases
ATCGTCTCAGTCGCGTCGTGACCGGAACCATCATCAACAGTGACGGTGGGAGAGGCGTTGCGGGGACTGTGCGAGTGGCA
CATCTCGTGGAGGAGATCTC

Downstream 100 bases:

>100_bases
GCGCCAATCACTTACCCATTCGGAAACTTTATACCTTGGTTGACGAAACCCATACAGTACTCGGGGAACGTGATCCTGAT
GGATATTTGAGGAAAGTCGT

Product: carbon monoxide dehydrogenase large chain (COdehydrogenase subunit L) (CO-DH L)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MIGQSVKRVEDFRFLTGQACYTRDVQIPGTAPLQALFLRSPYPAARITRILTEQAARVPGVVAVLTAAALPGHLRPIPLI
RKPPTSHHALPVIPLLADQVVRYQGEPIACVVATTEAVAQDALELIQVEYEPLPAVGQIDAAIGSDAPLVHPDLETNIAF
SATLRNGPVDDAFGKAAVVVRQRMHNNRVVPHPLEPRSVLASYDRETRQLTVWFSTQRPHHTRWFLSQILDYPENLIRVI
MPDVGGAFGCKEPIYPDEVLVCLASMLLQRPVRWTESRSEHFLSTTHGRDQLADLELAADADGRLLGLRGTVWLNIGAYL
YPNTSGVVLARTLPLLPGAYDIPAFDVTAHGVFTNTVPTGPYRGAGRPEAIYFIERLIDILASKLNIDPAEIRRRNFLEL
SPEKPTRTITGLSYDSGNFRQILDTALELSSYREHRLRQRNGDSEERLIGIGIAAYVELGGATPSTAAALEGSPPLWESA
TVTADPTGSIVVRVGTAGHGQGHETTFAQIAASVLGIPLSSIRVEFGDTATAPFGFGTFGTRSMTVGGSAVYLACQQLLQ
HAIKLAAEMLEANSSDVVYDRGYFYVRGLEDRSVSFQEVCHAAYFSLVPFRAGLQPGLQVTATYDPPNYTFATGVHVAVV
AIDRHTGQLDVLSYVGVDDCGRAINPMIVEGQLHGGIAQGIGQALFEHARYSRDGILMNPSLLDYALPRSTHLPTFETHL
IEFPSLSNPLGVKGIGEGGAIVGPVAITNAVHDALRCFGITHLNMPHTPEQLWRVIGRGEAGERREE

Sequences:

>Translated_787_residues
MIGQSVKRVEDFRFLTGQACYTRDVQIPGTAPLQALFLRSPYPAARITRILTEQAARVPGVVAVLTAAALPGHLRPIPLI
RKPPTSHHALPVIPLLADQVVRYQGEPIACVVATTEAVAQDALELIQVEYEPLPAVGQIDAAIGSDAPLVHPDLETNIAF
SATLRNGPVDDAFGKAAVVVRQRMHNNRVVPHPLEPRSVLASYDRETRQLTVWFSTQRPHHTRWFLSQILDYPENLIRVI
MPDVGGAFGCKEPIYPDEVLVCLASMLLQRPVRWTESRSEHFLSTTHGRDQLADLELAADADGRLLGLRGTVWLNIGAYL
YPNTSGVVLARTLPLLPGAYDIPAFDVTAHGVFTNTVPTGPYRGAGRPEAIYFIERLIDILASKLNIDPAEIRRRNFLEL
SPEKPTRTITGLSYDSGNFRQILDTALELSSYREHRLRQRNGDSEERLIGIGIAAYVELGGATPSTAAALEGSPPLWESA
TVTADPTGSIVVRVGTAGHGQGHETTFAQIAASVLGIPLSSIRVEFGDTATAPFGFGTFGTRSMTVGGSAVYLACQQLLQ
HAIKLAAEMLEANSSDVVYDRGYFYVRGLEDRSVSFQEVCHAAYFSLVPFRAGLQPGLQVTATYDPPNYTFATGVHVAVV
AIDRHTGQLDVLSYVGVDDCGRAINPMIVEGQLHGGIAQGIGQALFEHARYSRDGILMNPSLLDYALPRSTHLPTFETHL
IEFPSLSNPLGVKGIGEGGAIVGPVAITNAVHDALRCFGITHLNMPHTPEQLWRVIGRGEAGERREE
>Mature_787_residues
MIGQSVKRVEDFRFLTGQACYTRDVQIPGTAPLQALFLRSPYPAARITRILTEQAARVPGVVAVLTAAALPGHLRPIPLI
RKPPTSHHALPVIPLLADQVVRYQGEPIACVVATTEAVAQDALELIQVEYEPLPAVGQIDAAIGSDAPLVHPDLETNIAF
SATLRNGPVDDAFGKAAVVVRQRMHNNRVVPHPLEPRSVLASYDRETRQLTVWFSTQRPHHTRWFLSQILDYPENLIRVI
MPDVGGAFGCKEPIYPDEVLVCLASMLLQRPVRWTESRSEHFLSTTHGRDQLADLELAADADGRLLGLRGTVWLNIGAYL
YPNTSGVVLARTLPLLPGAYDIPAFDVTAHGVFTNTVPTGPYRGAGRPEAIYFIERLIDILASKLNIDPAEIRRRNFLEL
SPEKPTRTITGLSYDSGNFRQILDTALELSSYREHRLRQRNGDSEERLIGIGIAAYVELGGATPSTAAALEGSPPLWESA
TVTADPTGSIVVRVGTAGHGQGHETTFAQIAASVLGIPLSSIRVEFGDTATAPFGFGTFGTRSMTVGGSAVYLACQQLLQ
HAIKLAAEMLEANSSDVVYDRGYFYVRGLEDRSVSFQEVCHAAYFSLVPFRAGLQPGLQVTATYDPPNYTFATGVHVAVV
AIDRHTGQLDVLSYVGVDDCGRAINPMIVEGQLHGGIAQGIGQALFEHARYSRDGILMNPSLLDYALPRSTHLPTFETHL
IEFPSLSNPLGVKGIGEGGAIVGPVAITNAVHDALRCFGITHLNMPHTPEQLWRVIGRGEAGERREE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=790, Percent_Identity=25.3164556962025, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI91823271, Length=787, Percent_Identity=26.0482846251588, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1789230, Length=785, Percent_Identity=29.6815286624204, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1789246, Length=824, Percent_Identity=28.1553398058252, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1786478, Length=785, Percent_Identity=26.1146496815287, Blast_Score=142, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17540638, Length=798, Percent_Identity=23.5588972431078, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17539860, Length=755, Percent_Identity=23.5761589403974, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=742, Percent_Identity=22.2371967654987, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17737937, Length=747, Percent_Identity=26.2382864792503, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24647199, Length=806, Percent_Identity=23.697270471464, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647193, Length=800, Percent_Identity=23.625, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24647195, Length=806, Percent_Identity=24.317617866005, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24647197, Length=792, Percent_Identity=24.3686868686869, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85498; Mature: 85498

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGQSVKRVEDFRFLTGQACYTRDVQIPGTAPLQALFLRSPYPAARITRILTEQAARVPG
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCH
VVAVLTAAALPGHLRPIPLIRKPPTSHHALPVIPLLADQVVRYQGEPIACVVATTEAVAQ
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECHHHHHH
DALELIQVEYEPLPAVGQIDAAIGSDAPLVHPDLETNIAFSATLRNGPVDDAFGKAAVVV
HHHHHHHHCCCCCCCCCCHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RQRMHNNRVVPHPLEPRSVLASYDRETRQLTVWFSTQRPHHTRWFLSQILDYPENLIRVI
HHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHH
MPDVGGAFGCKEPIYPDEVLVCLASMLLQRPVRWTESRSEHFLSTTHGRDQLADLELAAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCCHHHCEEEECC
ADGRLLGLRGTVWLNIGAYLYPNTSGVVLARTLPLLPGAYDIPAFDVTAHGVFTNTVPTG
CCCCEEEECEEEEEEECEEEECCCCCEEEEEECCCCCCCCCCCCEEEEECCEEECCCCCC
PYRGAGRPEAIYFIERLIDILASKLNIDPAEIRRRNFLELSPEKPTRTITGLSYDSGNFR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCEEEEEECCCCCHH
QILDTALELSSYREHRLRQRNGDSEERLIGIGIAAYVELGGATPSTAAALEGSPPLWESA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHEEEEEECCCCCCCCEECCCCCCCCCCC
TVTADPTGSIVVRVGTAGHGQGHETTFAQIAASVLGIPLSSIRVEFGDTATAPFGFGTFG
EEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCC
TRSMTVGGSAVYLACQQLLQHAIKLAAEMLEANSSDVVYDRGYFYVRGLEDRSVSFQEVC
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCHHHHH
HAAYFSLVPFRAGLQPGLQVTATYDPPNYTFATGVHVAVVAIDRHTGQLDVLSYVGVDDC
HHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCEEEEEEEECCCCCEEEEEECCHHHH
GRAINPMIVEGQLHGGIAQGIGQALFEHARYSRDGILMNPSLLDYALPRSTHLPTFETHL
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCCCCCCHHHHH
IEFPSLSNPLGVKGIGEGGAIVGPVAITNAVHDALRCFGITHLNMPHTPEQLWRVIGRGE
EECCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCCC
AGERREE
CCCCCCC
>Mature Secondary Structure
MIGQSVKRVEDFRFLTGQACYTRDVQIPGTAPLQALFLRSPYPAARITRILTEQAARVPG
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCH
VVAVLTAAALPGHLRPIPLIRKPPTSHHALPVIPLLADQVVRYQGEPIACVVATTEAVAQ
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECHHHHHH
DALELIQVEYEPLPAVGQIDAAIGSDAPLVHPDLETNIAFSATLRNGPVDDAFGKAAVVV
HHHHHHHHCCCCCCCCCCHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RQRMHNNRVVPHPLEPRSVLASYDRETRQLTVWFSTQRPHHTRWFLSQILDYPENLIRVI
HHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHH
MPDVGGAFGCKEPIYPDEVLVCLASMLLQRPVRWTESRSEHFLSTTHGRDQLADLELAAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCCHHHCEEEECC
ADGRLLGLRGTVWLNIGAYLYPNTSGVVLARTLPLLPGAYDIPAFDVTAHGVFTNTVPTG
CCCCEEEECEEEEEEECEEEECCCCCEEEEEECCCCCCCCCCCCEEEEECCEEECCCCCC
PYRGAGRPEAIYFIERLIDILASKLNIDPAEIRRRNFLELSPEKPTRTITGLSYDSGNFR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCEEEEEECCCCCHH
QILDTALELSSYREHRLRQRNGDSEERLIGIGIAAYVELGGATPSTAAALEGSPPLWESA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHEEEEEECCCCCCCCEECCCCCCCCCCC
TVTADPTGSIVVRVGTAGHGQGHETTFAQIAASVLGIPLSSIRVEFGDTATAPFGFGTFG
EEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCC
TRSMTVGGSAVYLACQQLLQHAIKLAAEMLEANSSDVVYDRGYFYVRGLEDRSVSFQEVC
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCCCHHHHH
HAAYFSLVPFRAGLQPGLQVTATYDPPNYTFATGVHVAVVAIDRHTGQLDVLSYVGVDDC
HHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCEEEEEEEECCCCCEEEEEECCHHHH
GRAINPMIVEGQLHGGIAQGIGQALFEHARYSRDGILMNPSLLDYALPRSTHLPTFETHL
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCCCCCCHHHHH
IEFPSLSNPLGVKGIGEGGAIVGPVAITNAVHDALRCFGITHLNMPHTPEQLWRVIGRGE
EECCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCCC
AGERREE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]