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The map label for this gene is lutB [H]

Identifier: 221635608

GI number: 221635608

Start: 184412

End: 186673

Strand: Reverse

Name: lutB [H]

Synonym: trd_A0202

Alternate gene names: 221635608

Gene position: 186673-184412 (Counterclockwise)

Preceding gene: 221635612

Following gene: 221635607

Centisome position: 20.34

GC content: 70.6

Gene sequence:

>2262_bases
ATGCCGGCAAGAAGCAAAGCATTCCAGCGCGCGCTCGACACAGCGCTCGCCAACCGTGCCCAGCGCGAGGCGCTCGAGCG
GACGCTCACCCGCTATCGCCAGCGACGGGCCGAGGCGTTCGCCGACGTCGACTTCTCCGCCCTGCGCACCGATCTCCGTC
GGCGCAAGGAGGCGGCGATCGCCCAGCTTCCGGAGCTCGTCGCCGCGTTCCAGCGCCAGGCTGAGGCGGTCGGCGCGAGC
GTCTATCTGGCACGCACGGCCGAAGACGCCCGCCGCTACATCGCCGAACTCGTCCAGCGCACCGGGGCTCGCCTGGTCGT
CAAGTCGAAGTCGATGGCCACCGAGGAGATCCGCCTCAACGAGGCGCTCGAGCATGCCGGAGCCCGCGTCGTGGAGACCG
ACCTGGGTGAGTGGATCGTGCAGCTGGCTGGCGAGCGGCCGTCGCACCTGATCGGCCCAGCCATCCACAAGTCGCGCGAG
CAGATCGCCGAGCTCTTCTCCCGGGTGCTCGGTCGCCCGATCGCGCCCGATCCCCCGCAGCTGGTCGAGGTCGCCCGCCA
GGAACTCCGGCGCGCCTTCATCGAGGCAGATATCGGCATCACCGGCGCCAACGCCGCCATCGCCGAGACAGGCACGCTCG
TCATCGTCACCAACGAGGGGAACGCCGAACTGGTCGCCACTCTCCCCCCGATTCACGTCGCGGTGGTCGGTATCGACAAG
ATCGTCCCCACCCTGGACGATATCCCGCCCCTGCTGCGCGTCCTGCCCCGAGCCGGTGCTGCCCAGAAACTGACCGTCCG
CGTCCTCTTCGTCACCGGTCCGACCCGCACGGCCGACATCGAGATCCAGCTGGTGCGCGGCGCGCACGGGCCGCGCGAGC
TGCACATCGTCCTGCTCGACAATGGGCGCCTGGCGGCGCGCCAGGATCCGGAACTGGTCGATGCCCTCTATTGCATCCGC
TGCGGTGCCTGCTCGAACGTGTGCCCACCCTACCAGGTGGTCAGTGGGCATCTCTTCGGGCACATCTATACCGGCCCGAT
CGGCCTACCCTTGACCGCCATCCATCATGGGCTGGAGGCGGTAGCCGACCCTCAGAGTCTCTGCGTCTCCTGCAACGCCT
GCGAGACCGTCTGCCCGGTCGCCATCCCGATCCCGCGCCTCATTCTCGATGTGCGCGCCCGCGTGGCCGAGCGACTCGGG
CTCCCCTTCCTCAAGCGAGCCGTGCTCGAGCGCTGGAGCGACCCGCGCAGCGGCGACCGTTGGGCCCGGCTCGCGGCGCT
CGCCGCTGCACCGCTGGCCGACCGCGACGGCTTCCTCCGCGCGCTGCCGCTCGTCGATGGTGCGACGAGCAGCCGGCACC
TGCCGGCCCCGGCCCGGCGGCCATTGCGCGACCGGCTGCGGCACCTGGCGCCGGAGCTGGTCGGCGAACGAGCGGCCCCG
CCGCCCCGCTTCGCTGGCAGCCGCGTCGTCGGCCAGACGGTCGCCTTCTTCCCCGGCTGCCTCATCGATCGGCTGTTGCC
CGAGATGGGCGAAGCGGCCGTCCAGGTGCTGGAGGCCTGCGGCTGCCGCGTGGTCTTCCCGCTCGAACAGCACTGCTGCG
GATTGGTGGCCAACAACGCAGGCGACCGCCGACACGCCCGCACCATGGCACGACAGACGATCGCGCTCCTCGAGCGGGTC
GAGGCGGACTGGATCGTCACCCCCTCGACGAGCTGCTTCGCGGCGATCGCGCAGGACTACCAGCACCTCTTCCGCGACGA
GCCGGCGTGGCGCGAGCGCGCGGCCCGCGCTGCTGCCCGCGTGGTCGACTTCGTCACCTTCCTCGACCGGATCGCCCAGC
TCGGCCCGCAGGAGTGGTCGCGACCTGGCCCAGTCGTGACGTACCACGACAGCTGCCAGTCGGCCAATGCGCTCGGCTTG
CGCGAGCAGCCCCGGCGCCTCCTCAGCGAGGTCCTGGGCTGTACGGTAGTGGAGATGGAGGAATCGAGCTTCTGCTGCGG
GTTCGGCGGGACCTTCAGCCTGGACTACCCGGAGCTTTCGGCAGCCATCCTGGAGCGCAAGCTGCGCACGGCGGGCGCGA
CTGGCGCACCGCTCGTCGTAGCCGACAATCCGGGGTGTCTCATGCAGATCCGCGGCGGGCTGCACGCGCGGGGGAATCCG
CAACGAGCAGTCCACCTGGCGGAACTCGCCGCCGAGCGCCTGGCCGATCTCGCAGGCCCGCCAGTGGAACAGGGAGAACG
CACGATCCATGCACCGGCATGA

Upstream 100 bases:

>100_bases
AGCGCGGCGGACGACACTTCCGCACCGTCTCGCACAGCGCGCCCAAGCGCTACACTTGACAGGCAAGCGGACGCGTCAGG
GCAGGAGAGGAAGGAGAGCC

Downstream 100 bases:

>100_bases
GCACCAGCACACCCCGGCCAGTCTGCGGGCCGAGTACAAGCAGCGCGCGCTCGCCTGGGCGCTCGGCATCACGCTGGTCT
TCATGGTGGCAGAGGCGATC

Product: iron-sulfur cluster binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MPARSKAFQRALDTALANRAQREALERTLTRYRQRRAEAFADVDFSALRTDLRRRKEAAIAQLPELVAAFQRQAEAVGAS
VYLARTAEDARRYIAELVQRTGARLVVKSKSMATEEIRLNEALEHAGARVVETDLGEWIVQLAGERPSHLIGPAIHKSRE
QIAELFSRVLGRPIAPDPPQLVEVARQELRRAFIEADIGITGANAAIAETGTLVIVTNEGNAELVATLPPIHVAVVGIDK
IVPTLDDIPPLLRVLPRAGAAQKLTVRVLFVTGPTRTADIEIQLVRGAHGPRELHIVLLDNGRLAARQDPELVDALYCIR
CGACSNVCPPYQVVSGHLFGHIYTGPIGLPLTAIHHGLEAVADPQSLCVSCNACETVCPVAIPIPRLILDVRARVAERLG
LPFLKRAVLERWSDPRSGDRWARLAALAAAPLADRDGFLRALPLVDGATSSRHLPAPARRPLRDRLRHLAPELVGERAAP
PPRFAGSRVVGQTVAFFPGCLIDRLLPEMGEAAVQVLEACGCRVVFPLEQHCCGLVANNAGDRRHARTMARQTIALLERV
EADWIVTPSTSCFAAIAQDYQHLFRDEPAWRERAARAAARVVDFVTFLDRIAQLGPQEWSRPGPVVTYHDSCQSANALGL
REQPRRLLSEVLGCTVVEMEESSFCCGFGGTFSLDYPELSAAILERKLRTAGATGAPLVVADNPGCLMQIRGGLHARGNP
QRAVHLAELAAERLADLAGPPVEQGERTIHAPA

Sequences:

>Translated_753_residues
MPARSKAFQRALDTALANRAQREALERTLTRYRQRRAEAFADVDFSALRTDLRRRKEAAIAQLPELVAAFQRQAEAVGAS
VYLARTAEDARRYIAELVQRTGARLVVKSKSMATEEIRLNEALEHAGARVVETDLGEWIVQLAGERPSHLIGPAIHKSRE
QIAELFSRVLGRPIAPDPPQLVEVARQELRRAFIEADIGITGANAAIAETGTLVIVTNEGNAELVATLPPIHVAVVGIDK
IVPTLDDIPPLLRVLPRAGAAQKLTVRVLFVTGPTRTADIEIQLVRGAHGPRELHIVLLDNGRLAARQDPELVDALYCIR
CGACSNVCPPYQVVSGHLFGHIYTGPIGLPLTAIHHGLEAVADPQSLCVSCNACETVCPVAIPIPRLILDVRARVAERLG
LPFLKRAVLERWSDPRSGDRWARLAALAAAPLADRDGFLRALPLVDGATSSRHLPAPARRPLRDRLRHLAPELVGERAAP
PPRFAGSRVVGQTVAFFPGCLIDRLLPEMGEAAVQVLEACGCRVVFPLEQHCCGLVANNAGDRRHARTMARQTIALLERV
EADWIVTPSTSCFAAIAQDYQHLFRDEPAWRERAARAAARVVDFVTFLDRIAQLGPQEWSRPGPVVTYHDSCQSANALGL
REQPRRLLSEVLGCTVVEMEESSFCCGFGGTFSLDYPELSAAILERKLRTAGATGAPLVVADNPGCLMQIRGGLHARGNP
QRAVHLAELAAERLADLAGPPVEQGERTIHAPA
>Mature_752_residues
PARSKAFQRALDTALANRAQREALERTLTRYRQRRAEAFADVDFSALRTDLRRRKEAAIAQLPELVAAFQRQAEAVGASV
YLARTAEDARRYIAELVQRTGARLVVKSKSMATEEIRLNEALEHAGARVVETDLGEWIVQLAGERPSHLIGPAIHKSREQ
IAELFSRVLGRPIAPDPPQLVEVARQELRRAFIEADIGITGANAAIAETGTLVIVTNEGNAELVATLPPIHVAVVGIDKI
VPTLDDIPPLLRVLPRAGAAQKLTVRVLFVTGPTRTADIEIQLVRGAHGPRELHIVLLDNGRLAARQDPELVDALYCIRC
GACSNVCPPYQVVSGHLFGHIYTGPIGLPLTAIHHGLEAVADPQSLCVSCNACETVCPVAIPIPRLILDVRARVAERLGL
PFLKRAVLERWSDPRSGDRWARLAALAAAPLADRDGFLRALPLVDGATSSRHLPAPARRPLRDRLRHLAPELVGERAAPP
PRFAGSRVVGQTVAFFPGCLIDRLLPEMGEAAVQVLEACGCRVVFPLEQHCCGLVANNAGDRRHARTMARQTIALLERVE
ADWIVTPSTSCFAAIAQDYQHLFRDEPAWRERAARAAARVVDFVTFLDRIAQLGPQEWSRPGPVVTYHDSCQSANALGLR
EQPRRLLSEVLGCTVVEMEESSFCCGFGGTFSLDYPELSAAILERKLRTAGATGAPLVVADNPGCLMQIRGGLHARGNPQ
RAVHLAELAAERLADLAGPPVEQGERTIHAPA

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=346, Percent_Identity=43.0635838150289, Blast_Score=288, Evalue=9e-79,
Organism=Escherichia coli, GI1786497, Length=242, Percent_Identity=35.9504132231405, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI48994913, Length=402, Percent_Identity=24.8756218905473, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 81886; Mature: 81755

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARSKAFQRALDTALANRAQREALERTLTRYRQRRAEAFADVDFSALRTDLRRRKEAAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AQLPELVAAFQRQAEAVGASVYLARTAEDARRYIAELVQRTGARLVVKSKSMATEEIRLN
HHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
EALEHAGARVVETDLGEWIVQLAGERPSHLIGPAIHKSREQIAELFSRVLGRPIAPDPPQ
HHHHHCCCEEEHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LVEVARQELRRAFIEADIGITGANAAIAETGTLVIVTNEGNAELVATLPPIHVAVVGIDK
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCCCCEEEEECCCCEEEEEEHHH
IVPTLDDIPPLLRVLPRAGAAQKLTVRVLFVTGPTRTADIEIQLVRGAHGPRELHIVLLD
HHCCHHCCCHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEEEECCCCCCEEEEEEEC
NGRLAARQDPELVDALYCIRCGACSNVCPPYQVVSGHLFGHIYTGPIGLPLTAIHHGLEA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCHHEEEEEECCCCCHHHHHHHHHHH
VADPQSLCVSCNACETVCPVAIPIPRLILDVRARVAERLGLPFLKRAVLERWSDPRSGDR
HCCCHHHHEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
WARLAALAAAPLADRDGFLRALPLVDGATSSRHLPAPARRPLRDRLRHLAPELVGERAAP
HHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PPRFAGSRVVGQTVAFFPGCLIDRLLPEMGEAAVQVLEACGCRVVFPLEQHCCGLVANNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCC
GDRRHARTMARQTIALLERVEADWIVTPSTSCFAAIAQDYQHLFRDEPAWRERAARAAAR
CCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VVDFVTFLDRIAQLGPQEWSRPGPVVTYHDSCQSANALGLREQPRRLLSEVLGCTVVEME
HHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEC
ESSFCCGFGGTFSLDYPELSAAILERKLRTAGATGAPLVVADNPGCLMQIRGGLHARGNP
CCCEEECCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCH
QRAVHLAELAAERLADLAGPPVEQGERTIHAPA
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECCCC
>Mature Secondary Structure 
PARSKAFQRALDTALANRAQREALERTLTRYRQRRAEAFADVDFSALRTDLRRRKEAAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AQLPELVAAFQRQAEAVGASVYLARTAEDARRYIAELVQRTGARLVVKSKSMATEEIRLN
HHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
EALEHAGARVVETDLGEWIVQLAGERPSHLIGPAIHKSREQIAELFSRVLGRPIAPDPPQ
HHHHHCCCEEEHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LVEVARQELRRAFIEADIGITGANAAIAETGTLVIVTNEGNAELVATLPPIHVAVVGIDK
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEECCCCCEEEEECCCCEEEEEEHHH
IVPTLDDIPPLLRVLPRAGAAQKLTVRVLFVTGPTRTADIEIQLVRGAHGPRELHIVLLD
HHCCHHCCCHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEEEECCCCCCEEEEEEEC
NGRLAARQDPELVDALYCIRCGACSNVCPPYQVVSGHLFGHIYTGPIGLPLTAIHHGLEA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCHHEEEEEECCCCCHHHHHHHHHHH
VADPQSLCVSCNACETVCPVAIPIPRLILDVRARVAERLGLPFLKRAVLERWSDPRSGDR
HCCCHHHHEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
WARLAALAAAPLADRDGFLRALPLVDGATSSRHLPAPARRPLRDRLRHLAPELVGERAAP
HHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PPRFAGSRVVGQTVAFFPGCLIDRLLPEMGEAAVQVLEACGCRVVFPLEQHCCGLVANNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCC
GDRRHARTMARQTIALLERVEADWIVTPSTSCFAAIAQDYQHLFRDEPAWRERAARAAAR
CCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VVDFVTFLDRIAQLGPQEWSRPGPVVTYHDSCQSANALGLREQPRRLLSEVLGCTVVEME
HHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEC
ESSFCCGFGGTFSLDYPELSAAILERKLRTAGATGAPLVVADNPGCLMQIRGGLHARGNP
CCCEEECCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCH
QRAVHLAELAAERLADLAGPPVEQGERTIHAPA
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA