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The map label for this gene is cysS [H]

Identifier: 221633882

GI number: 221633882

Start: 1920045

End: 1921268

Strand: Reverse

Name: cysS [H]

Synonym: trd_1909

Alternate gene names: 221633882

Gene position: 1921268-1920045 (Counterclockwise)

Preceding gene: 221633885

Following gene: 221633881

Centisome position: 95.92

GC content: 64.87

Gene sequence:

>1224_bases
ATGCTGGAGGGAGCGAGCGAGGCCGTGCGATTGTTCAACTCGCTGACCGGGACGATCGAGCCCTTCGCCCCACTCGACGG
ACGAACCGTCCGCCTCTACGTTTGCGGCGTGACTCCCTACGATACGACTCACATGGGCCACGCCATGACGTATCTGGTCT
TCGACATCCTGAACCGCATCTGCCAGTACCATGGCTGGCGCGTCAAGTACGTTCAGAACATCACCGATATCGACGACGAC
ATCCTGCGCAAGGCACGCCAGGTCGGTGAGCCCTGGGATCGGCTGGGCGACCGTTACATCCGCCAGTTCCAGGAGGATCT
GAACGCCCTCAATGTGCTCTTCCCCTCCGTCTTCCCCCGGGCGACCGAGGAGATCCCGCTCATGATCGAGATCATTCAAA
AACTCCTCGAGCGCGGGGCAGCCTACATGCGTGACGGTAACGTCTACTTCCGCGTCGCCAGTGACCCTGACTATGGGCAC
CTCTGTCGCTGTAGCCGCGACGAGATGATCCGCCTTTCGGCCGAGCGGGGCGCCGACCCGCAGGATCCCCGCAAGGAAGA
CCCGCTCGATTTCCTTCTCTGGCAAGCAGCCCAACCAGGTGAACCGACCTGGGACAGTCCGTGGGGGCCTGGTCGGCCCG
GCTGGCACATCGAATGCAGTGCCATGGCCATGAAGTACCTGGGGCCGCAGATCGACGTGCACGGCGGCGGCTACGATCTC
ATCTATCCCCATCACGAGAGCGAGATCGCCCAGTCGGAAAGCTACACCGGTACGAGCCCCTTTGCCCGTTTCTGGGTCCA
TGTGGCCATGGTCGAGTACGAGGGTGCCAAGATGTCCAAGTCACTCGGCAACCTGGTCCTGGTCCGCGATACATTGCGGC
GGCACACTGGGGACGCAATCCGCCTGTATCTCCTCAGCCACCACTACCGGACACCCTTCGCCTACGAGGACGACGGCCCC
GCTCGCTTCGAGCCGCTCGTCCAACGGCTGCGCGAGGCGGTCACCGCCCCCGGCGGAAGCGGCAGTCCGCTCGATCTCGC
CCCGCTGCGCGACCAGTTGGCTGCTGCCCTCGCCGACGACCTGGATACGCCACGTGCGATTCAGCTGCTGGCCGATGCCG
CGGAGCGACTGCTCCGCGCGGCCCGCGAGGGCCAGGCGATCGAGCAGGCCCGGGAGCAACTGCGCGAGATGGGCAGTCTC
CTGGGGCTCACCGTGACCCGCTGA

Upstream 100 bases:

>100_bases
CCCGTTCACCGACCTGACCAGCCATCGTACCCTCCCTTCCCGAATCAGGGAACTCCGACCTGGCACTCCGATGGTAGGAT
ACGCGAAGCGAGCTGCCGGA

Downstream 100 bases:

>100_bases
CGCAGGGCCGTCTGGCGCGGCAGCCTCTGAGCACCGAGAACACTGTGCCCACTGACTTGCCCACCTCGGTTCTGCGGAAC
AGGATCAGCCGCATCGCTGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLEGASEAVRLFNSLTGTIEPFAPLDGRTVRLYVCGVTPYDTTHMGHAMTYLVFDILNRICQYHGWRVKYVQNITDIDDD
ILRKARQVGEPWDRLGDRYIRQFQEDLNALNVLFPSVFPRATEEIPLMIEIIQKLLERGAAYMRDGNVYFRVASDPDYGH
LCRCSRDEMIRLSAERGADPQDPRKEDPLDFLLWQAAQPGEPTWDSPWGPGRPGWHIECSAMAMKYLGPQIDVHGGGYDL
IYPHHESEIAQSESYTGTSPFARFWVHVAMVEYEGAKMSKSLGNLVLVRDTLRRHTGDAIRLYLLSHHYRTPFAYEDDGP
ARFEPLVQRLREAVTAPGGSGSPLDLAPLRDQLAAALADDLDTPRAIQLLADAAERLLRAAREGQAIEQAREQLREMGSL
LGLTVTR

Sequences:

>Translated_407_residues
MLEGASEAVRLFNSLTGTIEPFAPLDGRTVRLYVCGVTPYDTTHMGHAMTYLVFDILNRICQYHGWRVKYVQNITDIDDD
ILRKARQVGEPWDRLGDRYIRQFQEDLNALNVLFPSVFPRATEEIPLMIEIIQKLLERGAAYMRDGNVYFRVASDPDYGH
LCRCSRDEMIRLSAERGADPQDPRKEDPLDFLLWQAAQPGEPTWDSPWGPGRPGWHIECSAMAMKYLGPQIDVHGGGYDL
IYPHHESEIAQSESYTGTSPFARFWVHVAMVEYEGAKMSKSLGNLVLVRDTLRRHTGDAIRLYLLSHHYRTPFAYEDDGP
ARFEPLVQRLREAVTAPGGSGSPLDLAPLRDQLAAALADDLDTPRAIQLLADAAERLLRAAREGQAIEQAREQLREMGSL
LGLTVTR
>Mature_407_residues
MLEGASEAVRLFNSLTGTIEPFAPLDGRTVRLYVCGVTPYDTTHMGHAMTYLVFDILNRICQYHGWRVKYVQNITDIDDD
ILRKARQVGEPWDRLGDRYIRQFQEDLNALNVLFPSVFPRATEEIPLMIEIIQKLLERGAAYMRDGNVYFRVASDPDYGH
LCRCSRDEMIRLSAERGADPQDPRKEDPLDFLLWQAAQPGEPTWDSPWGPGRPGWHIECSAMAMKYLGPQIDVHGGGYDL
IYPHHESEIAQSESYTGTSPFARFWVHVAMVEYEGAKMSKSLGNLVLVRDTLRRHTGDAIRLYLLSHHYRTPFAYEDDGP
ARFEPLVQRLREAVTAPGGSGSPLDLAPLRDQLAAALADDLDTPRAIQLLADAAERLLRAAREGQAIEQAREQLREMGSL
LGLTVTR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=399, Percent_Identity=37.593984962406, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI10835051, Length=230, Percent_Identity=39.5652173913043, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI62240992, Length=230, Percent_Identity=39.5652173913043, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI303304987, Length=230, Percent_Identity=39.5652173913043, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI21269877, Length=230, Percent_Identity=39.5652173913043, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1786737, Length=397, Percent_Identity=40.8060453400504, Blast_Score=326, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17509797, Length=316, Percent_Identity=31.9620253164557, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17509795, Length=316, Percent_Identity=31.9620253164557, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324082, Length=303, Percent_Identity=32.3432343234323, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19922218, Length=405, Percent_Identity=36.5432098765432, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI19922364, Length=226, Percent_Identity=38.9380530973451, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 45981; Mature: 45981

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGASEAVRLFNSLTGTIEPFAPLDGRTVRLYVCGVTPYDTTHMGHAMTYLVFDILNRI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
CQYHGWRVKYVQNITDIDDDILRKARQVGEPWDRLGDRYIRQFQEDLNALNVLFPSVFPR
HHHCCCEEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATEEIPLMIEIIQKLLERGAAYMRDGNVYFRVASDPDYGHLCRCSRDEMIRLSAERGADP
CCCCCCHHHHHHHHHHHCCHHEEECCCEEEEEECCCCCCHHHCCCCHHHEEEEHHCCCCC
QDPRKEDPLDFLLWQAAQPGEPTWDSPWGPGRPGWHIECSAMAMKYLGPQIDVHGGGYDL
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCEEE
IYPHHESEIAQSESYTGTSPFARFWVHVAMVEYEGAKMSKSLGNLVLVRDTLRRHTGDAI
ECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHEECCHHHHHHHCCEEEEHHHHHHCCCCCE
RLYLLSHHYRTPFAYEDDGPARFEPLVQRLREAVTAPGGSGSPLDLAPLRDQLAAALADD
EEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
LDTPRAIQLLADAAERLLRAAREGQAIEQAREQLREMGSLLGLTVTR
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLEGASEAVRLFNSLTGTIEPFAPLDGRTVRLYVCGVTPYDTTHMGHAMTYLVFDILNRI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
CQYHGWRVKYVQNITDIDDDILRKARQVGEPWDRLGDRYIRQFQEDLNALNVLFPSVFPR
HHHCCCEEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATEEIPLMIEIIQKLLERGAAYMRDGNVYFRVASDPDYGHLCRCSRDEMIRLSAERGADP
CCCCCCHHHHHHHHHHHCCHHEEECCCEEEEEECCCCCCHHHCCCCHHHEEEEHHCCCCC
QDPRKEDPLDFLLWQAAQPGEPTWDSPWGPGRPGWHIECSAMAMKYLGPQIDVHGGGYDL
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCEEE
IYPHHESEIAQSESYTGTSPFARFWVHVAMVEYEGAKMSKSLGNLVLVRDTLRRHTGDAI
ECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHEECCHHHHHHHCCEEEEHHHHHHCCCCCE
RLYLLSHHYRTPFAYEDDGPARFEPLVQRLREAVTAPGGSGSPLDLAPLRDQLAAALADD
EEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
LDTPRAIQLLADAAERLLRAAREGQAIEQAREQLREMGSLLGLTVTR
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA