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The map label for this gene is nreC [H]

Identifier: 221633789

GI number: 221633789

Start: 1824860

End: 1825525

Strand: Reverse

Name: nreC [H]

Synonym: trd_1816

Alternate gene names: 221633789

Gene position: 1825525-1824860 (Counterclockwise)

Preceding gene: 221633790

Following gene: 221633788

Centisome position: 91.14

GC content: 64.11

Gene sequence:

>666_bases
ATGACGACGAACAAGATCCGCGTTCTCTTAGCTGATGATCACCCGATCGTGCGCGTCGGTCTGCGCGCTCTTTTGGAGGC
GGAGCCGGACATCGCGGTGGTCGGTGAAGCTGGAACGGCCGACGAAGCGGTCGAGTTAGCTCGTACCCTGCAACCCGATG
TGGCAGTCTTGGACATCAGCATGCCCGGCAACGGCTTGGAAGCCTTGCGCCGCATCGCCAGTCTCGGCCTCCCCACACGC
ACCTTGATTCTCACCGTGCACGCTGAGGAACGCTACCTCTTGCCAGTGCTGCAGGCAGGCGGGTCAGGATACGTGCGCAA
GTCGAGCTTGCACACCGACCTCGTCGAGGCGATCCGCCTGGTCGCCCGCGGTGAGGTCTTCATCGACCAGGCGGCCGCCC
GCACCCTGCTGCAGGGTTACCTGGACCATGCGCGGACCGGCGAGGTACAAGATCCGGCGCAACTCCTCTCTGAGCGGGAA
CGGGAAGTGCTTCGGCTCACCGCGGCCGGGTACACGGCGCAAGAGATCGCCGATCAACTGTTCCTCTCCCCCAAGACGGT
CGAGACCTACCGGCATCGCGTCATGCAGAAGCTGGGCTTTTCGCGCCGCTCCGAACTCGTGCGCTTCGCGCTCCGCATCG
GGTTGTTAGACCCTCAAGCCGAGTGA

Upstream 100 bases:

>100_bases
CGTTCGCCCTCGAGAGCGAGCCCGGCCACGGAACCCGCATCACGGTCGCGGTGCCACTCGAGTCACGAACCCAGTTCGCG
AGCACGACAGGAGTTCGAGC

Downstream 100 bases:

>100_bases
GACAGCCTGGCACAACGCGCGATCCGCGAGCAGAAGCCAGCGTGGATCCTGGCAACACAGCCACGTTCCTCGGCAGCTAG
GACGTACCGGGGAGAGCGTC

Product: response regulator uvrY

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTTNKIRVLLADDHPIVRVGLRALLEAEPDIAVVGEAGTADEAVELARTLQPDVAVLDISMPGNGLEALRRIASLGLPTR
TLILTVHAEERYLLPVLQAGGSGYVRKSSLHTDLVEAIRLVARGEVFIDQAAARTLLQGYLDHARTGEVQDPAQLLSERE
REVLRLTAAGYTAQEIADQLFLSPKTVETYRHRVMQKLGFSRRSELVRFALRIGLLDPQAE

Sequences:

>Translated_221_residues
MTTNKIRVLLADDHPIVRVGLRALLEAEPDIAVVGEAGTADEAVELARTLQPDVAVLDISMPGNGLEALRRIASLGLPTR
TLILTVHAEERYLLPVLQAGGSGYVRKSSLHTDLVEAIRLVARGEVFIDQAAARTLLQGYLDHARTGEVQDPAQLLSERE
REVLRLTAAGYTAQEIADQLFLSPKTVETYRHRVMQKLGFSRRSELVRFALRIGLLDPQAE
>Mature_220_residues
TTNKIRVLLADDHPIVRVGLRALLEAEPDIAVVGEAGTADEAVELARTLQPDVAVLDISMPGNGLEALRRIASLGLPTRT
LILTVHAEERYLLPVLQAGGSGYVRKSSLHTDLVEAIRLVARGEVFIDQAAARTLLQGYLDHARTGEVQDPAQLLSERER
EVLRLTAAGYTAQEIADQLFLSPKTVETYRHRVMQKLGFSRRSELVRFALRIGLLDPQAE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=40, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=35.8208955223881, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=37.7450980392157, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=36.4130434782609, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=28.8461538461538, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=31.4285714285714, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24305; Mature: 24174

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNKIRVLLADDHPIVRVGLRALLEAEPDIAVVGEAGTADEAVELARTLQPDVAVLDIS
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEE
MPGNGLEALRRIASLGLPTRTLILTVHAEERYLLPVLQAGGSGYVRKSSLHTDLVEAIRL
CCCCHHHHHHHHHHCCCCCEEEEEEEECCCCEEHHHHHCCCCCCEEHHHHHHHHHHHHHH
VARGEVFIDQAAARTLLQGYLDHARTGEVQDPAQLLSEREREVLRLTAAGYTAQEIADQL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLSPKTVETYRHRVMQKLGFSRRSELVRFALRIGLLDPQAE
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTNKIRVLLADDHPIVRVGLRALLEAEPDIAVVGEAGTADEAVELARTLQPDVAVLDIS
CCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEE
MPGNGLEALRRIASLGLPTRTLILTVHAEERYLLPVLQAGGSGYVRKSSLHTDLVEAIRL
CCCCHHHHHHHHHHCCCCCEEEEEEEECCCCEEHHHHHCCCCCCEEHHHHHHHHHHHHHH
VARGEVFIDQAAARTLLQGYLDHARTGEVQDPAQLLSEREREVLRLTAAGYTAQEIADQL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLSPKTVETYRHRVMQKLGFSRRSELVRFALRIGLLDPQAE
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]