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The map label for this gene is nreB [H]

Identifier: 221633790

GI number: 221633790

Start: 1825522

End: 1826589

Strand: Reverse

Name: nreB [H]

Synonym: trd_1817

Alternate gene names: 221633790

Gene position: 1826589-1825522 (Counterclockwise)

Preceding gene: 221633791

Following gene: 221633789

Centisome position: 91.19

GC content: 62.64

Gene sequence:

>1068_bases
ATGACAACACGAATTGCGACGATCACTGGCTATCTCGTTCGGTCGCTCGCTCATCTTCCCATCTTTTACAAGGTCTTGAT
CGCCAATTCTCTGATCGTGGTCACCGGGGCCGTCGCCGGAACCACGCTCACGCTGTTGAGTACGGGAAGCACTGAGCACC
TTTTCGAACTCGTCGCACTCTTCACGATCGCGGGAACCTTCCTCTCGGTTCTCATCAACTGGATCGTTCTGCGCGCGGCC
TTTCGCCCCATCGATGTCCTGGAGCAGACAGCCGACGAGGTGCGACGCGGCAACTTCCACGTCCGGGCACCATCCGTTCC
GCTCAGTGACCCCGATCTGGAGAACTTGACCGCGACGTTCAACGCGATGCTGGATACGCTGGTCGGCTACCAGCAACGGC
TGCGGGAACTCTCCCAGCGCGTCCTGACCGCCCAGGAAGAGGAGCGCCAGCGGATCGCCCGCGAGCTGCACGATGATCCG
GCACAGAGCCTGACCGCACTGCTGGTTCTGCTCAAGATGCTGCACGATCGGCAACAGCCGACCGATGGGCGAACCCTCCA
GGAACTGATCGACCTGACGACAGCGACCCTCGAGTCGATCCGCGCCATCGCCCAGGAACTGCGCCCTCCCGTACTGGACG
ACTTTGGTCTCGCGGCAGCACTGGAAGGCTTGGCAGCGCAGTACTGGCAACGTTTCGGTCTCCCGGTTCATGTCTATGTC
CGCGGGCAACGGCAGCGATTGTCACCGGAGATCGAGCTCGCACTCTATCGGATCGCGCAAGAGGCATTGACCAATGTGGC
CAAGCACGCGGACGCGACGTACGCAACGATCGACCTGCAGTTCCGGGAGGGCACTGTTTCGTTGCGGATCGAGGACGACG
GCCGGGGCTTCGAACCGCGAGAGGGCCTCGGACGTGGACTCGGACTGTTCGGGATGCGCGAGCGCGCCGAACTGGTTCAC
GGCACGTTCGCCCTCGAGAGCGAGCCCGGCCACGGAACCCGCATCACGGTCGCGGTGCCACTCGAGTCACGAACCCAGTT
CGCGAGCACGACAGGAGTTCGAGCATGA

Upstream 100 bases:

>100_bases
TGCCCCAGCTCGACCGCAGCCAGCAGCCCACCACGGTCGACACCAGAGCAAGAAGAAAAAGAAGAAGCGCCGCTGAGCGG
CACGAGGACCACCACTGACC

Downstream 100 bases:

>100_bases
CGACGAACAAGATCCGCGTTCTCTTAGCTGATGATCACCCGATCGTGCGCGTCGGTCTGCGCGCTCTTTTGGAGGCGGAG
CCGGACATCGCGGTGGTCGG

Product: putative transmembrane two component system sensor kinase transcription regulator protein

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTTRIATITGYLVRSLAHLPIFYKVLIANSLIVVTGAVAGTTLTLLSTGSTEHLFELVALFTIAGTFLSVLINWIVLRAA
FRPIDVLEQTADEVRRGNFHVRAPSVPLSDPDLENLTATFNAMLDTLVGYQQRLRELSQRVLTAQEEERQRIARELHDDP
AQSLTALLVLLKMLHDRQQPTDGRTLQELIDLTTATLESIRAIAQELRPPVLDDFGLAAALEGLAAQYWQRFGLPVHVYV
RGQRQRLSPEIELALYRIAQEALTNVAKHADATYATIDLQFREGTVSLRIEDDGRGFEPREGLGRGLGLFGMRERAELVH
GTFALESEPGHGTRITVAVPLESRTQFASTTGVRA

Sequences:

>Translated_355_residues
MTTRIATITGYLVRSLAHLPIFYKVLIANSLIVVTGAVAGTTLTLLSTGSTEHLFELVALFTIAGTFLSVLINWIVLRAA
FRPIDVLEQTADEVRRGNFHVRAPSVPLSDPDLENLTATFNAMLDTLVGYQQRLRELSQRVLTAQEEERQRIARELHDDP
AQSLTALLVLLKMLHDRQQPTDGRTLQELIDLTTATLESIRAIAQELRPPVLDDFGLAAALEGLAAQYWQRFGLPVHVYV
RGQRQRLSPEIELALYRIAQEALTNVAKHADATYATIDLQFREGTVSLRIEDDGRGFEPREGLGRGLGLFGMRERAELVH
GTFALESEPGHGTRITVAVPLESRTQFASTTGVRA
>Mature_354_residues
TTRIATITGYLVRSLAHLPIFYKVLIANSLIVVTGAVAGTTLTLLSTGSTEHLFELVALFTIAGTFLSVLINWIVLRAAF
RPIDVLEQTADEVRRGNFHVRAPSVPLSDPDLENLTATFNAMLDTLVGYQQRLRELSQRVLTAQEEERQRIARELHDDPA
QSLTALLVLLKMLHDRQQPTDGRTLQELIDLTTATLESIRAIAQELRPPVLDDFGLAAALEGLAAQYWQRFGLPVHVYVR
GQRQRLSPEIELALYRIAQEALTNVAKHADATYATIDLQFREGTVSLRIEDDGRGFEPREGLGRGLGLFGMRERAELVHG
TFALESEPGHGTRITVAVPLESRTQFASTTGVRA

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=228, Percent_Identity=33.7719298245614, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788812, Length=261, Percent_Identity=29.5019157088123, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787474, Length=241, Percent_Identity=28.6307053941909, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39326; Mature: 39194

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00555 ICOSAH_VIR_COAT_S

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRIATITGYLVRSLAHLPIFYKVLIANSLIVVTGAVAGTTLTLLSTGSTEHLFELVAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHEEEEEECCCHHHHHHHHHH
FTIAGTFLSVLINWIVLRAAFRPIDVLEQTADEVRRGNFHVRAPSVPLSDPDLENLTATF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHH
NAMLDTLVGYQQRLRELSQRVLTAQEEERQRIARELHDDPAQSLTALLVLLKMLHDRQQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
TDGRTLQELIDLTTATLESIRAIAQELRPPVLDDFGLAAALEGLAAQYWQRFGLPVHVYV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
RGQRQRLSPEIELALYRIAQEALTNVAKHADATYATIDLQFREGTVSLRIEDDGRGFEPR
ECCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEEEEECCCCCCCCH
EGLGRGLGLFGMRERAELVHGTFALESEPGHGTRITVAVPLESRTQFASTTGVRA
HHHCCCCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCC
>Mature Secondary Structure 
TTRIATITGYLVRSLAHLPIFYKVLIANSLIVVTGAVAGTTLTLLSTGSTEHLFELVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHEEEEEECCCHHHHHHHHHH
FTIAGTFLSVLINWIVLRAAFRPIDVLEQTADEVRRGNFHVRAPSVPLSDPDLENLTATF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHH
NAMLDTLVGYQQRLRELSQRVLTAQEEERQRIARELHDDPAQSLTALLVLLKMLHDRQQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
TDGRTLQELIDLTTATLESIRAIAQELRPPVLDDFGLAAALEGLAAQYWQRFGLPVHVYV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
RGQRQRLSPEIELALYRIAQEALTNVAKHADATYATIDLQFREGTVSLRIEDDGRGFEPR
ECCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEEEEECCCCCCCCH
EGLGRGLGLFGMRERAELVHGTFALESEPGHGTRITVAVPLESRTQFASTTGVRA
HHHCCCCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]