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The map label for this gene is mer [H]

Identifier: 221633524

GI number: 221633524

Start: 1527400

End: 1528362

Strand: Reverse

Name: mer [H]

Synonym: trd_1546

Alternate gene names: 221633524

Gene position: 1528362-1527400 (Counterclockwise)

Preceding gene: 221633526

Following gene: 221633523

Centisome position: 76.3

GC content: 66.46

Gene sequence:

>963_bases
ATGCCGTGGCCGCGCGTCGCCATCGACCAGCCTGATCGCAACAATGCTGTCGGTGCTCTCGCCGCGATCCAGCGCTTGGA
GGCAGCCGGAGTACCTGCCATCTGGACCGTGACCGGTGGCCGGACGATCGATGCCTTGACCGTCTACGCGGCCGCCGCAG
TGCGGTCCGAGCGGATCATCCTGGGTACGGGAATCATCCCGACCTATCCTCGCCACCCGTTCGTGACGGCGCAGCAGACA
CTCGCCGTGCATCAGTTGGCGCCAGGCCGGATTCGCCTGGGACTCGGGCCGAGCCATCGGCCGATCATCGAAGGCTCGCT
CGGTATCCCGATGGAGCGTCCCCTGGCGCACCTGCGGGAGTATGTGACGATCGTGCGCGGTCTCCTCTGGGACGGGCAGA
TCGACTTTCAAGGCGAATTTTTCCGGGTCCGCCAGCGCCTCCCGGAGACGGCACCGGTGCCGATCTACACCTCCGCACTG
CGCCCGAAAGCGTTCCAGTTGGCCGGCGAAATCGCCGACGGCGTGATCTCCTGGATGTGCCCACCCAGTTACATCCACGA
GCGTGCGGTTCCGGCGCTGGAGAACGGGGCCCGAGCTGCCGGGCGCACCCGCCGGCCCCGTCTCGTGGTGCAGGTACCGG
TGGTCATGACGACCGATGTCGCGGTCATGCGTGAGAAGGCACGACCAGTCGTCGGTCTCTATGGGCGCATGCCTTTCTAT
GCCCAAATGTTCGAGACGGCCGGGTTCCCGCTGGAAAACGGTACTCCGAGCGATGCTCTGCTCGACCATCTGGTGGTGTG
GGGTGACCGCGACACGGTGGGAGAACGGCTGGCGCAACTGCTCGAGGGCGGTATCGACGAGTTGTTGACGATGCTCATCC
CAGTCGCCGACCACCTGGCCGAGGAAGCGGAACTCGCCGCTGTGCTGGCGGCGCTCGACCGGCGCTTCGGCTGGAGCGGG
TGA

Upstream 100 bases:

>100_bases
GCAACCGTCACCACGCAAGTGCCGTCCTCGCACAGTCATGCTAGACTGGCGCGGACAACTCGTGCGGGAGAGGTCGTCCC
ACGAAGGGAGGCAGAGCAGG

Downstream 100 bases:

>100_bases
CGATCTGGGAGACGCTGCGGTAGGATAAAACGGGCGTTGTGGCCGCGGACGGGAGGAGAAGCACGGTCATGGCGGACAAT
CCGGCGATGGTTTCCATGGG

Product: luciferase-like monooxygenase superfamily protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPWPRVAIDQPDRNNAVGALAAIQRLEAAGVPAIWTVTGGRTIDALTVYAAAAVRSERIILGTGIIPTYPRHPFVTAQQT
LAVHQLAPGRIRLGLGPSHRPIIEGSLGIPMERPLAHLREYVTIVRGLLWDGQIDFQGEFFRVRQRLPETAPVPIYTSAL
RPKAFQLAGEIADGVISWMCPPSYIHERAVPALENGARAAGRTRRPRLVVQVPVVMTTDVAVMREKARPVVGLYGRMPFY
AQMFETAGFPLENGTPSDALLDHLVVWGDRDTVGERLAQLLEGGIDELLTMLIPVADHLAEEAELAAVLAALDRRFGWSG

Sequences:

>Translated_320_residues
MPWPRVAIDQPDRNNAVGALAAIQRLEAAGVPAIWTVTGGRTIDALTVYAAAAVRSERIILGTGIIPTYPRHPFVTAQQT
LAVHQLAPGRIRLGLGPSHRPIIEGSLGIPMERPLAHLREYVTIVRGLLWDGQIDFQGEFFRVRQRLPETAPVPIYTSAL
RPKAFQLAGEIADGVISWMCPPSYIHERAVPALENGARAAGRTRRPRLVVQVPVVMTTDVAVMREKARPVVGLYGRMPFY
AQMFETAGFPLENGTPSDALLDHLVVWGDRDTVGERLAQLLEGGIDELLTMLIPVADHLAEEAELAAVLAALDRRFGWSG
>Mature_319_residues
PWPRVAIDQPDRNNAVGALAAIQRLEAAGVPAIWTVTGGRTIDALTVYAAAAVRSERIILGTGIIPTYPRHPFVTAQQTL
AVHQLAPGRIRLGLGPSHRPIIEGSLGIPMERPLAHLREYVTIVRGLLWDGQIDFQGEFFRVRQRLPETAPVPIYTSALR
PKAFQLAGEIADGVISWMCPPSYIHERAVPALENGARAAGRTRRPRLVVQVPVVMTTDVAVMREKARPVVGLYGRMPFYA
QMFETAGFPLENGTPSDALLDHLVVWGDRDTVGERLAQLLEGGIDELLTMLIPVADHLAEEAELAAVLAALDRRFGWSG

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 34971; Mature: 34840

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWPRVAIDQPDRNNAVGALAAIQRLEAAGVPAIWTVTGGRTIDALTVYAAAAVRSERII
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEE
LGTGIIPTYPRHPFVTAQQTLAVHQLAPGRIRLGLGPSHRPIIEGSLGIPMERPLAHLRE
EECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
YVTIVRGLLWDGQIDFQGEFFRVRQRLPETAPVPIYTSALRPKAFQLAGEIADGVISWMC
HHHHHHHHHCCCEECCCHHHHHHHHHCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHCC
PPSYIHERAVPALENGARAAGRTRRPRLVVQVPVVMTTDVAVMREKARPVVGLYGRMPFY
CHHHHHHHCCCHHHCCCHHCCCCCCCEEEEEECCEEECHHHHHHHHCCCEEEHHCCCHHH
AQMFETAGFPLENGTPSDALLDHLVVWGDRDTVGERLAQLLEGGIDELLTMLIPVADHLA
HHHHHHCCCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EEAELAAVLAALDRRFGWSG
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PWPRVAIDQPDRNNAVGALAAIQRLEAAGVPAIWTVTGGRTIDALTVYAAAAVRSERII
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEE
LGTGIIPTYPRHPFVTAQQTLAVHQLAPGRIRLGLGPSHRPIIEGSLGIPMERPLAHLRE
EECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
YVTIVRGLLWDGQIDFQGEFFRVRQRLPETAPVPIYTSALRPKAFQLAGEIADGVISWMC
HHHHHHHHHCCCEECCCHHHHHHHHHCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHCC
PPSYIHERAVPALENGARAAGRTRRPRLVVQVPVVMTTDVAVMREKARPVVGLYGRMPFY
CHHHHHHHCCCHHHCCCHHCCCCCCCEEEEEECCEEECHHHHHHHHCCCEEEHHCCCHHH
AQMFETAGFPLENGTPSDALLDHLVVWGDRDTVGERLAQLLEGGIDELLTMLIPVADHLA
HHHHHHCCCCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EEAELAAVLAALDRRFGWSG
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]