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The map label for this gene is argD [H]

Identifier: 221633493

GI number: 221633493

Start: 1495663

End: 1496850

Strand: Reverse

Name: argD [H]

Synonym: trd_1515

Alternate gene names: 221633493

Gene position: 1496850-1495663 (Counterclockwise)

Preceding gene: 221633494

Following gene: 221633492

Centisome position: 74.73

GC content: 67.68

Gene sequence:

>1188_bases
ATGACGGCACGATCGACGAGCGCTATCCTCCAGCTGGACGAGTCGCTGCAGCCGCCGCTCTACGCCAAGCGGGGTATCGT
GCTGGTTCGTGGCGAGGGCGCCTGGCTCTACGACAGTGACGGCCAGCGGTACCTCGACCTGATGAGCAACTACGGCGTGA
ATATCCTGGGTCACGCGCACCCACGCGTCACGGCAGCGATCGTGGCTCAGGCGAGTCGGCTCTTGAGCTGTCACCAGTCG
TTCGCCTCGGATGTCCGGGCAGCGTTTCTCGAGAAGCTGCTCGCGGTCGCACCGCATGGACTTTCGCGGGCGTTCCTGAG
CAACTCGGGTGCCGAGGCGGTCGAGGCTGCGCTCAAGTTCGCCTGGGCCGTGACCGGTCGGCGCAAGGTCGTCGCGGCGA
AGCGTGGGTATCACGGGCGCACGCTCGGAGCGCTGGCGGCTACCGGCGAACCCAAGTACCGGCAACCGTTCCTGGCTGTC
CTGCCGGAGGTGGTTCACGTCCCCTACGGTGATGCCGCTGCACTGGCCGAGGCAGTGGACAACGACACGGCGGCGGTGAT
CCTGGAGCCGGTGCAGGGCGAGGGCGGCATTTACCCGGCGGAACCGGGCTACCTTGCGGAGGTGAGACGGATCACCCGCG
AGGCTGGTGCCTTGCTCGTGCTCGACGAGGTCCAGTCCGCCTTCCGCACGGGAGCCTGGTTCGCCTGCGAGCATGCCGGC
GTGTCGCCGGATCTCCTCTGTGTCGCCAAGGGTCTGGCCAACGGTGTTCCGATCGGTGCGACCCTGATGACGGAAGATGT
CGCCCTCGCTTTGCCGGCCGGGGTACACGGGAGCACGTTCGGCGGGAACCCGCTGGCCTGCGCAGCAGGTCTGGCCACGC
TGGAAACGCTGGAGGACGACCGGCTCATCCCGGGAGCAGCGGAACTGGGCCTGTACTTCCGCCAGCAGTTGCTTGCGCTC
GGTCATCCCCTCGTGCGCGATGTGCGAGGGATCGGGCTCATGCTCGGCCTGGACCTCAAGGTCCGGTCGACCCCGGTCTT
GAAAGCGCTGCAAGAGCGTGGCGTCCTGGCCTTGCCGGCGGGGACAACGGTCGTCCGCTTGCTCCCACCGCTGATCTTGT
CGCGCGACGAAGTCGACCTAGCGGTCGCGCGTATCGCGCAGGCACTCGATGCGGTCCGCGAGCGCTGA

Upstream 100 bases:

>100_bases
GCGTCGTCTTCGCCGATGCACGCCTCCCGCAGCCGATCCAGCGTGCCCTGGCGGGGGTCGGAACTGTGCTGACCGCTGGT
AGTCGTGTCGAGGTGCGGCC

Downstream 100 bases:

>100_bases
ACGTGGGGGTGCGATGAGCGAGCAGCGACCAGGCGAGCAAACGCGCATCGTCCTGCGCAGTTTCGGCGTCATGGTGACGA
CGTTCGAGGAGCAGATGACG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTARSTSAILQLDESLQPPLYAKRGIVLVRGEGAWLYDSDGQRYLDLMSNYGVNILGHAHPRVTAAIVAQASRLLSCHQS
FASDVRAAFLEKLLAVAPHGLSRAFLSNSGAEAVEAALKFAWAVTGRRKVVAAKRGYHGRTLGALAATGEPKYRQPFLAV
LPEVVHVPYGDAAALAEAVDNDTAAVILEPVQGEGGIYPAEPGYLAEVRRITREAGALLVLDEVQSAFRTGAWFACEHAG
VSPDLLCVAKGLANGVPIGATLMTEDVALALPAGVHGSTFGGNPLACAAGLATLETLEDDRLIPGAAELGLYFRQQLLAL
GHPLVRDVRGIGLMLGLDLKVRSTPVLKALQERGVLALPAGTTVVRLLPPLILSRDEVDLAVARIAQALDAVRER

Sequences:

>Translated_395_residues
MTARSTSAILQLDESLQPPLYAKRGIVLVRGEGAWLYDSDGQRYLDLMSNYGVNILGHAHPRVTAAIVAQASRLLSCHQS
FASDVRAAFLEKLLAVAPHGLSRAFLSNSGAEAVEAALKFAWAVTGRRKVVAAKRGYHGRTLGALAATGEPKYRQPFLAV
LPEVVHVPYGDAAALAEAVDNDTAAVILEPVQGEGGIYPAEPGYLAEVRRITREAGALLVLDEVQSAFRTGAWFACEHAG
VSPDLLCVAKGLANGVPIGATLMTEDVALALPAGVHGSTFGGNPLACAAGLATLETLEDDRLIPGAAELGLYFRQQLLAL
GHPLVRDVRGIGLMLGLDLKVRSTPVLKALQERGVLALPAGTTVVRLLPPLILSRDEVDLAVARIAQALDAVRER
>Mature_394_residues
TARSTSAILQLDESLQPPLYAKRGIVLVRGEGAWLYDSDGQRYLDLMSNYGVNILGHAHPRVTAAIVAQASRLLSCHQSF
ASDVRAAFLEKLLAVAPHGLSRAFLSNSGAEAVEAALKFAWAVTGRRKVVAAKRGYHGRTLGALAATGEPKYRQPFLAVL
PEVVHVPYGDAAALAEAVDNDTAAVILEPVQGEGGIYPAEPGYLAEVRRITREAGALLVLDEVQSAFRTGAWFACEHAGV
SPDLLCVAKGLANGVPIGATLMTEDVALALPAGVHGSTFGGNPLACAAGLATLETLEDDRLIPGAAELGLYFRQQLLALG
HPLVRDVRGIGLMLGLDLKVRSTPVLKALQERGVLALPAGTTVVRLLPPLILSRDEVDLAVARIAQALDAVRER

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=33.245382585752, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=35.3535353535354, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=29.8642533936652, Blast_Score=178, Evalue=6e-45,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=29.8329355608592, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=30.8612440191388, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=29.1169451073986, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=29.7650130548303, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI145693181, Length=428, Percent_Identity=38.5514018691589, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1788044, Length=390, Percent_Identity=38.2051282051282, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789759, Length=387, Percent_Identity=35.4005167958656, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=33.5839598997494, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1786991, Length=396, Percent_Identity=34.5959595959596, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1787560, Length=390, Percent_Identity=33.5897435897436, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786349, Length=329, Percent_Identity=32.8267477203647, Blast_Score=138, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=398, Percent_Identity=31.1557788944724, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=29.2792792792793, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI25144274, Length=390, Percent_Identity=27.4358974358974, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=26.9503546099291, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=426, Percent_Identity=24.1784037558685, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71981843, Length=154, Percent_Identity=29.2207792207792, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=32.8358208955224, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323470, Length=418, Percent_Identity=31.8181818181818, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=406, Percent_Identity=28.0788177339901, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357415, Length=372, Percent_Identity=33.8709677419355, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=30.787037037037, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28574759, Length=434, Percent_Identity=30.6451612903226, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=31.5165876777251, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=24.2924528301887, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=24.2924528301887, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=24.2924528301887, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41684; Mature: 41552

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARSTSAILQLDESLQPPLYAKRGIVLVRGEGAWLYDSDGQRYLDLMSNYGVNILGHAH
CCCCHHHHHHHHHHHCCCCCCHHCCEEEEECCCEEEECCCCHHHHHHHHCCCCEEEECCC
PRVTAAIVAQASRLLSCHQSFASDVRAAFLEKLLAVAPHGLSRAFLSNSGAEAVEAALKF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHH
AWAVTGRRKVVAAKRGYHGRTLGALAATGEPKYRQPFLAVLPEVVHVPYGDAAALAEAVD
HHHHCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHC
NDTAAVILEPVQGEGGIYPAEPGYLAEVRRITREAGALLVLDEVQSAFRTGAWFACEHAG
CCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCEEEEECCC
VSPDLLCVAKGLANGVPIGATLMTEDVALALPAGVHGSTFGGNPLACAAGLATLETLEDD
CCHHHHHHHHHHCCCCCCCHHHHHCCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
RLIPGAAELGLYFRQQLLALGHPLVRDVRGIGLMLGLDLKVRSTPVLKALQERGVLALPA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEECCEEECCCHHHHHHHHCCEEEECC
GTTVVRLLPPLILSRDEVDLAVARIAQALDAVRER
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARSTSAILQLDESLQPPLYAKRGIVLVRGEGAWLYDSDGQRYLDLMSNYGVNILGHAH
CCCHHHHHHHHHHHCCCCCCHHCCEEEEECCCEEEECCCCHHHHHHHHCCCCEEEECCC
PRVTAAIVAQASRLLSCHQSFASDVRAAFLEKLLAVAPHGLSRAFLSNSGAEAVEAALKF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHH
AWAVTGRRKVVAAKRGYHGRTLGALAATGEPKYRQPFLAVLPEVVHVPYGDAAALAEAVD
HHHHCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHC
NDTAAVILEPVQGEGGIYPAEPGYLAEVRRITREAGALLVLDEVQSAFRTGAWFACEHAG
CCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCEEEEECCC
VSPDLLCVAKGLANGVPIGATLMTEDVALALPAGVHGSTFGGNPLACAAGLATLETLEDD
CCHHHHHHHHHHCCCCCCCHHHHHCCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
RLIPGAAELGLYFRQQLLALGHPLVRDVRGIGLMLGLDLKVRSTPVLKALQERGVLALPA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEECCEEECCCHHHHHHHHCCEEEECC
GTTVVRLLPPLILSRDEVDLAVARIAQALDAVRER
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11489859 [H]