| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is yjgC [H]
Identifier: 221633449
GI number: 221633449
Start: 1458228
End: 1460663
Strand: Reverse
Name: yjgC [H]
Synonym: trd_1471
Alternate gene names: 221633449
Gene position: 1460663-1458228 (Counterclockwise)
Preceding gene: 221633450
Following gene: 221633448
Centisome position: 72.92
GC content: 66.01
Gene sequence:
>2436_bases ATGACCGCGACCACCGAAAGCCGCCTCGTCACCGTCACGATCGATGGACAGCAATACACTGTGCCGGAAGGTCTGACCAT CCTGGAGGCCTGCCGGATGGTCGGCATCGAAGTGCCCAACCTTTGTTATCAACCGCTCTTGCGACCCTGGGGCTCCTGCC GGATCTGCACGGTGGAAATCCTGGGTCGTCGCGGCGGGCTGGTCGAGTCCTGCGCGGCGCAGGTGCGCGACGGGATGGAG ATCGCTACCAAGTCGCCGGCCTGCGAGGAGGCGCGGCGGTTCGTCCTGCAGCTCTATCTCATCGACCACGCGCTCGATTG CCCGACCTGCGATAAGTCCGGTGAATGTTATCTCCAGGACAATACCTATTATCACAATGTCCACACCAATCCCTTCCGGC GCCCCAAGCTCGCTCGTCCCTACAAGCATTTGAGCGAGTACATCGACTACAAGTGGGAACGCTGCATTCTTTGCGCGCGT TGCACCCGCGTCTGTGACGAGATGATCGGGGTCACGGCGATCGAAGTGCTGCGCCGCGGACTCGAGGGCGAGATCGGCAG CGCCTGGAATATCGATCTGACCCGCACCACGTGCACGTCCTGCGGGATGTGCATCGCAGTCTGTCCGGTAGGTGCGCTGA CTGACCGGCGCTTCGCGCACCATCCCTGGGAGTTGGACGCCACGGAGACGATCTGTGGCTTTTGCGATGTGGGCTGCACA CTGAATGTCGAGCACAACCGTGGCCTCGTACGTCGGATCACTCATCTCTGGGAGCGCGGCGTCAACTACGGCTACACCTG CGTACGTGGCAAGTGGGGATACGAGCAGGTGCAACACCCAGTGCGGCTGGACAGCGCCTGGGTGCGCGAGGGTGACGAAC TCGTTCCGATCGAGCTCGCCGAGGCGCTCGACCGTGCTGCCGAGTTGCTGCGACCGTATCGCGGAACAGCGTTCGCGCTC CTGGCGTCGCCCGATCGGACGAATGAAGATCTGTATCTGTTGCAGCGGTTCGCTCGCCAGGTAATGCGTTCGCCGCATGT GGACACGCTGGTCTCTCCGGCGCAGCGAGCGGTCGATGCCGCGCTCACGGCGTCGTTCGGATTGCCGGTGAGCACCAACT CGATCCAGGAAGTCTTCACCGATACCGGATGTCTCTTGGTCGTGGGGCCGAACATCGGTCAGCATGCCCCGGTCGCGAGC TACTGGCATTCGTGGGCGCGACTCTATCGTGAAACCGCGCTGGTGGTGGTGAGCGCCGACGAGTTCCCACTCTTCCACCG GGCCGATGTGTGGTTGCGTATCCGCCCGGGAACGGAGGCGGTGGTGCTCGCGGCGATGGCCCGCGTGATCCGCGACCGCG GATTGGCTCGCCCGGTCGAAGGGGCGACAGGGCTGAGCGAATTCATGGCCTCTCTCGACTCGATCGATCCGGTCGCGGCG GCCGAGGCAGCCGGGGTGAGCTTGGCGGCGCTGGAGCGCGCAGCCGTGCTGTATGCGACTGGTGGGCGCGGCACGGATGC TTCTCCCTATCCACCGAGCCAGATCCAGCACACGCTCGCCCACGCGCAGCACGGCGATATCGCTGCGGCGGCGTTGCTGG CCAACGATCTGGCCTTGCTCACCGGTAATATCGGACAGGCTGGCGCGGGCGTGGTCGCGTTCCGCGGTCCGGCGAATGCG CAAGGTGCGCTGGACATGGGCTGCCACCCAGACTGGCTACCGGGGTATCGCTCGCCGGAGGATGCGGCGATGCGACAGGA ATTGGCAGTCCTCTGGGCCGAGACGGGTGGCAATGGAAGCGGCTCGACCGAGTTGCCGAGCGGGCCAGGATGGGGCTACG AGGAACTGGTGGCAGCGATCGAGCGGGGTGAGGTGCGTGCGCTGTACGTGGCGGCGAACTCGCACGCGTATGCCACAGCG CTCGATGAGCGGTTCGTGGCCGCGCTGGATCGGCTCGACGTACTGATCGTGGAAGACAGTTTCCCCGGTCCGCTGACTGA GCGAGCGCACGTCGTGCTCCCGGTCACCATGTTCCTGGAGCAGGACGGGACGATGACGACCGCCGATCGAGCAGTGCAGC GGCTGCGGCGCGCGGTCGATCCGCCGGGGGAGGCGCGTCCGAGTTGGCAGCATGTCCAAGAGTTGGCACGCCGGCTCGGC TATCGCTGGAACACGCGCCACGCGGTGCAGCTCTTCCAAGAAATCGCCCGCGCTGTGCCCGGCTATCGCGGCATCACGTT CCCGCGGCTCGAGCGTGGGCCCATCGCCTGGCCGGCAGCGCCAGGCGATCGAGCGCGCCAGACGCTGCGCATCGGTCAGA ACGTTCCCGGCGGCGGGTGGGCGGTCTGGTTGGGCAACGGGATCGCGCTCAGCGATGCCTGGCTGCGGTTGGACAGCGCG CCGCTGCGCGGCCGGGTCGCCTTCCGAACGCCCTGA
Upstream 100 bases:
>100_bases GATCCGGGGAGCAGCCTCCTGCGGTGGTAAGATCAGGGCAGGTGAAGCGGAAAGAGGCCGAGTTCGGCCTGTTCTCCTGT ATCCGAGAGGGGCCAGTCGC
Downstream 100 bases:
>100_bases CAGCGATCGCTCGAGGAGGCGCACGATGGTCTTACAGGACATTCGCGGCTTTCTGGTCACGCTGCGGCACTTTTTCCAGC GACCAGTGACGATTCAGTAT
Product: formate dehydrogenase subunit alpha-like protein
Products: CO2; NADH
Alternate protein names: NA
Number of amino acids: Translated: 811; Mature: 810
Protein sequence:
>811_residues MTATTESRLVTVTIDGQQYTVPEGLTILEACRMVGIEVPNLCYQPLLRPWGSCRICTVEILGRRGGLVESCAAQVRDGME IATKSPACEEARRFVLQLYLIDHALDCPTCDKSGECYLQDNTYYHNVHTNPFRRPKLARPYKHLSEYIDYKWERCILCAR CTRVCDEMIGVTAIEVLRRGLEGEIGSAWNIDLTRTTCTSCGMCIAVCPVGALTDRRFAHHPWELDATETICGFCDVGCT LNVEHNRGLVRRITHLWERGVNYGYTCVRGKWGYEQVQHPVRLDSAWVREGDELVPIELAEALDRAAELLRPYRGTAFAL LASPDRTNEDLYLLQRFARQVMRSPHVDTLVSPAQRAVDAALTASFGLPVSTNSIQEVFTDTGCLLVVGPNIGQHAPVAS YWHSWARLYRETALVVVSADEFPLFHRADVWLRIRPGTEAVVLAAMARVIRDRGLARPVEGATGLSEFMASLDSIDPVAA AEAAGVSLAALERAAVLYATGGRGTDASPYPPSQIQHTLAHAQHGDIAAAALLANDLALLTGNIGQAGAGVVAFRGPANA QGALDMGCHPDWLPGYRSPEDAAMRQELAVLWAETGGNGSGSTELPSGPGWGYEELVAAIERGEVRALYVAANSHAYATA LDERFVAALDRLDVLIVEDSFPGPLTERAHVVLPVTMFLEQDGTMTTADRAVQRLRRAVDPPGEARPSWQHVQELARRLG YRWNTRHAVQLFQEIARAVPGYRGITFPRLERGPIAWPAAPGDRARQTLRIGQNVPGGGWAVWLGNGIALSDAWLRLDSA PLRGRVAFRTP
Sequences:
>Translated_811_residues MTATTESRLVTVTIDGQQYTVPEGLTILEACRMVGIEVPNLCYQPLLRPWGSCRICTVEILGRRGGLVESCAAQVRDGME IATKSPACEEARRFVLQLYLIDHALDCPTCDKSGECYLQDNTYYHNVHTNPFRRPKLARPYKHLSEYIDYKWERCILCAR CTRVCDEMIGVTAIEVLRRGLEGEIGSAWNIDLTRTTCTSCGMCIAVCPVGALTDRRFAHHPWELDATETICGFCDVGCT LNVEHNRGLVRRITHLWERGVNYGYTCVRGKWGYEQVQHPVRLDSAWVREGDELVPIELAEALDRAAELLRPYRGTAFAL LASPDRTNEDLYLLQRFARQVMRSPHVDTLVSPAQRAVDAALTASFGLPVSTNSIQEVFTDTGCLLVVGPNIGQHAPVAS YWHSWARLYRETALVVVSADEFPLFHRADVWLRIRPGTEAVVLAAMARVIRDRGLARPVEGATGLSEFMASLDSIDPVAA AEAAGVSLAALERAAVLYATGGRGTDASPYPPSQIQHTLAHAQHGDIAAAALLANDLALLTGNIGQAGAGVVAFRGPANA QGALDMGCHPDWLPGYRSPEDAAMRQELAVLWAETGGNGSGSTELPSGPGWGYEELVAAIERGEVRALYVAANSHAYATA LDERFVAALDRLDVLIVEDSFPGPLTERAHVVLPVTMFLEQDGTMTTADRAVQRLRRAVDPPGEARPSWQHVQELARRLG YRWNTRHAVQLFQEIARAVPGYRGITFPRLERGPIAWPAAPGDRARQTLRIGQNVPGGGWAVWLGNGIALSDAWLRLDSA PLRGRVAFRTP >Mature_810_residues TATTESRLVTVTIDGQQYTVPEGLTILEACRMVGIEVPNLCYQPLLRPWGSCRICTVEILGRRGGLVESCAAQVRDGMEI ATKSPACEEARRFVLQLYLIDHALDCPTCDKSGECYLQDNTYYHNVHTNPFRRPKLARPYKHLSEYIDYKWERCILCARC TRVCDEMIGVTAIEVLRRGLEGEIGSAWNIDLTRTTCTSCGMCIAVCPVGALTDRRFAHHPWELDATETICGFCDVGCTL NVEHNRGLVRRITHLWERGVNYGYTCVRGKWGYEQVQHPVRLDSAWVREGDELVPIELAEALDRAAELLRPYRGTAFALL ASPDRTNEDLYLLQRFARQVMRSPHVDTLVSPAQRAVDAALTASFGLPVSTNSIQEVFTDTGCLLVVGPNIGQHAPVASY WHSWARLYRETALVVVSADEFPLFHRADVWLRIRPGTEAVVLAAMARVIRDRGLARPVEGATGLSEFMASLDSIDPVAAA EAAGVSLAALERAAVLYATGGRGTDASPYPPSQIQHTLAHAQHGDIAAAALLANDLALLTGNIGQAGAGVVAFRGPANAQ GALDMGCHPDWLPGYRSPEDAAMRQELAVLWAETGGNGSGSTELPSGPGWGYEELVAAIERGEVRALYVAANSHAYATAL DERFVAALDRLDVLIVEDSFPGPLTERAHVVLPVTMFLEQDGTMTTADRAVQRLRRAVDPPGEARPSWQHVQELARRLGY RWNTRHAVQLFQEIARAVPGYRGITFPRLERGPIAWPAAPGDRARQTLRIGQNVPGGGWAVWLGNGIALSDAWLRLDSAP LRGRVAFRTP
Specific function: Decomposes Formic Acid To Hydrogen And Carbon Dioxide Under Anaerobic Conditions In The Absence Of Exogenous Electron Acceptors. [C]
COG id: COG3383
COG function: function code R; Uncharacterized anaerobic dehydrogenase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]
Homologues:
Organism=Homo sapiens, GI33519475, Length=419, Percent_Identity=31.5035799522673, Blast_Score=173, Evalue=7e-43, Organism=Escherichia coli, GI3868721, Length=554, Percent_Identity=28.7003610108303, Blast_Score=201, Evalue=1e-52, Organism=Escherichia coli, GI145693161, Length=315, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=3e-40, Organism=Escherichia coli, GI1788534, Length=545, Percent_Identity=23.1192660550459, Blast_Score=86, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17565758, Length=419, Percent_Identity=27.2076372315036, Blast_Score=148, Evalue=1e-35, Organism=Caenorhabditis elegans, GI32566231, Length=419, Percent_Identity=27.2076372315036, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=33.0677290836653, Blast_Score=137, Evalue=3e-32, Organism=Drosophila melanogaster, GI24640559, Length=287, Percent_Identity=31.3588850174216, Blast_Score=131, Evalue=2e-30, Organism=Drosophila melanogaster, GI24640557, Length=287, Percent_Identity=31.3588850174216, Blast_Score=131, Evalue=2e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017896 - InterPro: IPR017900 - InterPro: IPR009010 - InterPro: IPR012675 - InterPro: IPR001041 - InterPro: IPR006478 - InterPro: IPR006657 - InterPro: IPR006656 - InterPro: IPR006963 - InterPro: IPR019574 [H]
Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]
EC number: 1.2.1.2
Molecular weight: Translated: 88932; Mature: 88801
Theoretical pI: Translated: 6.39; Mature: 6.39
Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 2.8 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTATTESRLVTVTIDGQQYTVPEGLTILEACRMVGIEVPNLCYQPLLRPWGSCRICTVEI CCCCCCCEEEEEEECCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEE LGRRGGLVESCAAQVRDGMEIATKSPACEEARRFVLQLYLIDHALDCPTCDKSGECYLQD CCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC NTYYHNVHTNPFRRPKLARPYKHLSEYIDYKWERCILCARCTRVCDEMIGVTAIEVLRRG CCEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC LEGEIGSAWNIDLTRTTCTSCGMCIAVCPVGALTDRRFAHHPWELDATETICGFCDVGCT CCCCCCCEEEEEEEHHHHHHCCCCHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCCCE LNVEHNRGLVRRITHLWERGVNYGYTCVRGKWGYEQVQHPVRLDSAWVREGDELVPIELA EEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHCCCCCCHHHHH EALDRAAELLRPYRGTAFALLASPDRTNEDLYLLQRFARQVMRSPHVDTLVSPAQRAVDA HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH ALTASFGLPVSTNSIQEVFTDTGCLLVVGPNIGQHAPVASYWHSWARLYRETALVVVSAD HHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECC EFPLFHRADVWLRIRPGTEAVVLAAMARVIRDRGLARPVEGATGLSEFMASLDSIDPVAA CCCCEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHH AEAAGVSLAALERAAVLYATGGRGTDASPYPPSQIQHTLAHAQHGDIAAAALLANDLALL HHHCCCHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHEE TGNIGQAGAGVVAFRGPANAQGALDMGCHPDWLPGYRSPEDAAMRQELAVLWAETGGNGS ECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCC GSTELPSGPGWGYEELVAAIERGEVRALYVAANSHAYATALDERFVAALDRLDVLIVEDS CCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECC FPGPLTERAHVVLPVTMFLEQDGTMTTADRAVQRLRRAVDPPGEARPSWQHVQELARRLG CCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC YRWNTRHAVQLFQEIARAVPGYRGITFPRLERGPIAWPAAPGDRARQTLRIGQNVPGGGW CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCE AVWLGNGIALSDAWLRLDSAPLRGRVAFRTP EEEECCCEEECHHHHEECCCCCCCEEEECCC >Mature Secondary Structure TATTESRLVTVTIDGQQYTVPEGLTILEACRMVGIEVPNLCYQPLLRPWGSCRICTVEI CCCCCCEEEEEEECCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEE LGRRGGLVESCAAQVRDGMEIATKSPACEEARRFVLQLYLIDHALDCPTCDKSGECYLQD CCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC NTYYHNVHTNPFRRPKLARPYKHLSEYIDYKWERCILCARCTRVCDEMIGVTAIEVLRRG CCEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC LEGEIGSAWNIDLTRTTCTSCGMCIAVCPVGALTDRRFAHHPWELDATETICGFCDVGCT CCCCCCCEEEEEEEHHHHHHCCCCHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCCCE LNVEHNRGLVRRITHLWERGVNYGYTCVRGKWGYEQVQHPVRLDSAWVREGDELVPIELA EEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHCCCCCCHHHHH EALDRAAELLRPYRGTAFALLASPDRTNEDLYLLQRFARQVMRSPHVDTLVSPAQRAVDA HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH ALTASFGLPVSTNSIQEVFTDTGCLLVVGPNIGQHAPVASYWHSWARLYRETALVVVSAD HHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECC EFPLFHRADVWLRIRPGTEAVVLAAMARVIRDRGLARPVEGATGLSEFMASLDSIDPVAA CCCCEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHH AEAAGVSLAALERAAVLYATGGRGTDASPYPPSQIQHTLAHAQHGDIAAAALLANDLALL HHHCCCHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHEE TGNIGQAGAGVVAFRGPANAQGALDMGCHPDWLPGYRSPEDAAMRQELAVLWAETGGNGS ECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCC GSTELPSGPGWGYEELVAAIERGEVRALYVAANSHAYATALDERFVAALDRLDVLIVEDS CCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECC FPGPLTERAHVVLPVTMFLEQDGTMTTADRAVQRLRRAVDPPGEARPSWQHVQELARRLG CCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC YRWNTRHAVQLFQEIARAVPGYRGITFPRLERGPIAWPAAPGDRARQTLRIGQNVPGGGW CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCE AVWLGNGIALSDAWLRLDSAPLRGRVAFRTP EEEECCCEEECHHHHEECCCCCCCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+ [C]
Metal ions: Fe; Mo; Se [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.19 {3-pyridinecarboxaldehyde-NAD+}} 0.032 {NAD+}} 1.16 {3-acetylpyridine-NAD+}} 0.54 {deamino-NAD+}} 0.17 {thio-NAD+}} [C]
Substrates: formate; NAD+
Specific reaction: formate + NAD+ = CO2 + NADH
General reaction: Redox reaction [C]
Inhibitor: Azide; Br-; Cl-; CN-; F-; HCO3-; HCOS-; NO2-; NO3-; OCN-; SCN- [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9579062; 9384377 [H]