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The map label for this gene is kynB [H]

Identifier: 221633298

GI number: 221633298

Start: 1310307

End: 1310951

Strand: Reverse

Name: kynB [H]

Synonym: trd_1318

Alternate gene names: 221633298

Gene position: 1310951-1310307 (Counterclockwise)

Preceding gene: 221633299

Following gene: 221633297

Centisome position: 65.45

GC content: 64.19

Gene sequence:

>645_bases
GTGAACACGATGCGGGTGTACGACATTTCGCACCCGATCGAGTCGGACATGCTGGTTTTCCCCGGTGATCCCGAGGTGTG
TCTGGAAACGGTAGCAGCCTCGGCGCCGTGGCGGGTGACACGTGTGACGATGGGCAGCCATTCCGGGACGCACGTCGATG
CACCGGCTCATTTCTTTCCCGACGGACGATCGATTACCGATTATCCTGCGGAGCGGTTCGTCGTGCCCGCCGTCCTGCTC
CAGCTTCCGAACTTGGCCGATGACGAGGCGATCTCGCTGGCGTTGCTCCGGCAGCATCTGGGCAGCCCTCCCCGTGGGGC
TGCTGTCCTCCTGGCGACTGGCTGGGATCGTTACTGGGGATCGGACCGCTATTTCGTTCATCCCTACCTCGCTGAGGAAG
CGGCGACCTGGTTGGTGGCCTCAGGGATCGGGCTCGTCGGCATCGACGCACTCAACATCGATTCGACGGTGCAGGGAACG
TCCCATGCGCACGCGTGCCTGCTCGGGGCGGATGTCTTGATCGTCGAAAACCTGCGAGGGCTCCGCGCGATCCCGGCAGG
AGATCGATACCTCCTCGTGTGTCTTCCTCTGCCGATCGCCGGTGCGGACGGTGCGCCGGCCCGGGCGGTGTTGTTGGAGC
GGTAA

Upstream 100 bases:

>100_bases
TGTGCATCAATCCCGGTTCGGCCTACGGTGAGGGAGTCCTTCATGGAGCGCTCGTCCGATTGGAGGACGATCGCGTGGCC
AGCTATCAGCTCGTGAGCGG

Downstream 100 bases:

>100_bases
GGGGGTGAGGGGTTGTGATCGAGAGAGGAGGAGAGCGGATGCTGGACAAGAGTCAGGCCAAAGGGCCGCGCGTCTTTACA
CGTGCTGCGACTGGTCTCGT

Product: putative cyclase superfamily

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNTMRVYDISHPIESDMLVFPGDPEVCLETVAASAPWRVTRVTMGSHSGTHVDAPAHFFPDGRSITDYPAERFVVPAVLL
QLPNLADDEAISLALLRQHLGSPPRGAAVLLATGWDRYWGSDRYFVHPYLAEEAATWLVASGIGLVGIDALNIDSTVQGT
SHAHACLLGADVLIVENLRGLRAIPAGDRYLLVCLPLPIAGADGAPARAVLLER

Sequences:

>Translated_214_residues
MNTMRVYDISHPIESDMLVFPGDPEVCLETVAASAPWRVTRVTMGSHSGTHVDAPAHFFPDGRSITDYPAERFVVPAVLL
QLPNLADDEAISLALLRQHLGSPPRGAAVLLATGWDRYWGSDRYFVHPYLAEEAATWLVASGIGLVGIDALNIDSTVQGT
SHAHACLLGADVLIVENLRGLRAIPAGDRYLLVCLPLPIAGADGAPARAVLLER
>Mature_214_residues
MNTMRVYDISHPIESDMLVFPGDPEVCLETVAASAPWRVTRVTMGSHSGTHVDAPAHFFPDGRSITDYPAERFVVPAVLL
QLPNLADDEAISLALLRQHLGSPPRGAAVLLATGWDRYWGSDRYFVHPYLAEEAATWLVASGIGLVGIDALNIDSTVQGT
SHAHACLLGADVLIVENLRGLRAIPAGDRYLLVCLPLPIAGADGAPARAVLLER

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 22966; Mature: 22966

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTMRVYDISHPIESDMLVFPGDPEVCLETVAASAPWRVTRVTMGSHSGTHVDAPAHFFP
CCCEEEEECCCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCCEECC
DGRSITDYPAERFVVPAVLLQLPNLADDEAISLALLRQHLGSPPRGAAVLLATGWDRYWG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCC
SDRYFVHPYLAEEAATWLVASGIGLVGIDALNIDSTVQGTSHAHACLLGADVLIVENLRG
CCCEEECHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCC
LRAIPAGDRYLLVCLPLPIAGADGAPARAVLLER
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MNTMRVYDISHPIESDMLVFPGDPEVCLETVAASAPWRVTRVTMGSHSGTHVDAPAHFFP
CCCEEEEECCCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCCEECC
DGRSITDYPAERFVVPAVLLQLPNLADDEAISLALLRQHLGSPPRGAAVLLATGWDRYWG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCC
SDRYFVHPYLAEEAATWLVASGIGLVGIDALNIDSTVQGTSHAHACLLGADVLIVENLRG
CCCEEECHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCC
LRAIPAGDRYLLVCLPLPIAGADGAPARAVLLER
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA