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The map label for this gene is nagD [C]

Identifier: 221633266

GI number: 221633266

Start: 1275945

End: 1277141

Strand: Reverse

Name: nagD [C]

Synonym: trd_1283

Alternate gene names: 221633266

Gene position: 1277141-1275945 (Counterclockwise)

Preceding gene: 221633270

Following gene: 221633252

Centisome position: 63.76

GC content: 66.17

Gene sequence:

>1197_bases
ATGCGCGCGCTGGATTTCGATGCCTGGTTGCTCGACTTGGACGGCGTCGTCTACGTGGGCGATCGACTGCTGCCGGGAGT
CGCCGAGGCGCTCGCCACGCTGCGAGCGACGGGCAAGCATCTTCGTTTCCTGACCAACGATCCACGACCGACGCGCGAGC
AACTCGCCGAGCGCCTGCGTCGCCTCGGCATCGATGTGGCGGTCGAGGAAGTCGTGACATGCGGCTGGGCGACCGCCCGC
CTGCTGCCCCAACTCGGTATCGGCAGCGCTTACGTGGTCGGGAGCGTGGGACTAGCTGAGGAGTTGGCCCGCGTAGGTAT
CACCGTGGTAGACGACGGGATACCTGATGCAGTCGTCGTGGGAGCGGACGAGCGGCTGGATTTCCGGAGAGTCGTCAAGG
GGAGTCTTTTGGTCCAACGCGGCGCTCGTTTCGTCGCGACCAATGCCGATGCATCCTACCCGATGCCTTTCGGAACGGTG
CCAGCTACCGGAGCAGTCGTCTGTGCCATCCGTCTCGCGACCGGACAGCGCCCGCTCGTCGTCGGCAAACCGGAACCGCT
GATGTTCCAGCTCGCGCTCGAGACACTGCCAATGGGTGCGACGGCGCTGGTCATTGGTGACCGGGTGGACAGCGATGTCC
TCGGCGCGCATCGCGTGGGACTCCCCGCGGTTCTCCTGGCAAGAGAGGCGCCGGCTTTCCCCGCGCGCGACTTGCGTCGC
CCGGAGAGAATCGCCACCTCGCTCGCCGAACTCGTGGCGACTTCCCCAGAAATACCGCCTCGGCCGGTCGACGACGTGAG
GTGGCCTGAACGTGTCGTGGCCGGTGTCATCCTGGTCGTCCTCGACGAGACGATCGAGATGGTCGCGCTGGTACCGGTAG
CCAGCAGCTGGATGCTGCCCTGGGTCGCACTGGAGCCGCTCGAATCATTTGCCGACGCTGCCGAGCGATTGCTTGCGCGG
ATCCTCCCGTCGCAGCCGGTCACGCTGACCTTCCGGCCAGAACTGGTCGACGGAACCGTGCTCGTCAGCGATGTCGATGG
GGCGCTCATCCAGCTGGCTGGACCAGTGGTCGTTGTTCGCATCACTGGGAGCATGCTCGCCGGTGGCGCGGAGTGGCGAG
AGATCGCGCGTGCCCGCCAGTTGCTCCCCGCCGATCAGGCGCGGGTGCTGGAAAGCGCGTTGAGTGCGCTCGATTGA

Upstream 100 bases:

>100_bases
AGGGCGGGCGAGTCCAAGTCGGTTCGGGTCGGGTGACGGACACGCCAGCGACAACAGGATGCTCGGGCGGTCGGCATACT
CGGTGCGGAAAGGGGGAAGG

Downstream 100 bases:

>100_bases
GCGCGGGCGACGAGCAGCGCGGTGTCGGGATCGGTGATCGCGATCCATCGCCGCTCGTGGAATCCAGTCCTTTCCAGCCA
TGACTCCAGATCCTGCGCCG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRALDFDAWLLDLDGVVYVGDRLLPGVAEALATLRATGKHLRFLTNDPRPTREQLAERLRRLGIDVAVEEVVTCGWATAR
LLPQLGIGSAYVVGSVGLAEELARVGITVVDDGIPDAVVVGADERLDFRRVVKGSLLVQRGARFVATNADASYPMPFGTV
PATGAVVCAIRLATGQRPLVVGKPEPLMFQLALETLPMGATALVIGDRVDSDVLGAHRVGLPAVLLAREAPAFPARDLRR
PERIATSLAELVATSPEIPPRPVDDVRWPERVVAGVILVVLDETIEMVALVPVASSWMLPWVALEPLESFADAAERLLAR
ILPSQPVTLTFRPELVDGTVLVSDVDGALIQLAGPVVVVRITGSMLAGGAEWREIARARQLLPADQARVLESALSALD

Sequences:

>Translated_398_residues
MRALDFDAWLLDLDGVVYVGDRLLPGVAEALATLRATGKHLRFLTNDPRPTREQLAERLRRLGIDVAVEEVVTCGWATAR
LLPQLGIGSAYVVGSVGLAEELARVGITVVDDGIPDAVVVGADERLDFRRVVKGSLLVQRGARFVATNADASYPMPFGTV
PATGAVVCAIRLATGQRPLVVGKPEPLMFQLALETLPMGATALVIGDRVDSDVLGAHRVGLPAVLLAREAPAFPARDLRR
PERIATSLAELVATSPEIPPRPVDDVRWPERVVAGVILVVLDETIEMVALVPVASSWMLPWVALEPLESFADAAERLLAR
ILPSQPVTLTFRPELVDGTVLVSDVDGALIQLAGPVVVVRITGSMLAGGAEWREIARARQLLPADQARVLESALSALD
>Mature_398_residues
MRALDFDAWLLDLDGVVYVGDRLLPGVAEALATLRATGKHLRFLTNDPRPTREQLAERLRRLGIDVAVEEVVTCGWATAR
LLPQLGIGSAYVVGSVGLAEELARVGITVVDDGIPDAVVVGADERLDFRRVVKGSLLVQRGARFVATNADASYPMPFGTV
PATGAVVCAIRLATGQRPLVVGKPEPLMFQLALETLPMGATALVIGDRVDSDVLGAHRVGLPAVLLAREAPAFPARDLRR
PERIATSLAELVATSPEIPPRPVDDVRWPERVVAGVILVVLDETIEMVALVPVASSWMLPWVALEPLESFADAAERLLAR
ILPSQPVTLTFRPELVDGTVLVSDVDGALIQLAGPVVVVRITGSMLAGGAEWREIARARQLLPADQARVLESALSALD

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=234, Percent_Identity=34.6153846153846, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI108796653, Length=252, Percent_Identity=34.5238095238095, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI14149777, Length=221, Percent_Identity=33.0316742081448, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI269847098, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786890, Length=245, Percent_Identity=34.2857142857143, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17558880, Length=292, Percent_Identity=27.7397260273973, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562458, Length=292, Percent_Identity=27.7397260273973, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560956, Length=252, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17562356, Length=248, Percent_Identity=28.2258064516129, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210059, Length=253, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563050, Length=247, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319965, Length=237, Percent_Identity=27.8481012658228, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666141, Length=246, Percent_Identity=31.3008130081301, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656326, Length=244, Percent_Identity=26.2295081967213, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24656330, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920940, Length=221, Percent_Identity=27.6018099547511, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666137, Length=259, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00702 Hydrolase; PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 42514; Mature: 42514

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALDFDAWLLDLDGVVYVGDRLLPGVAEALATLRATGKHLRFLTNDPRPTREQLAERLR
CCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHH
RLGIDVAVEEVVTCGWATARLLPQLGIGSAYVVGSVGLAEELARVGITVVDDGIPDAVVV
HCCCHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEECCCCCEEEE
GADERLDFRRVVKGSLLVQRGARFVATNADASYPMPFGTVPATGAVVCAIRLATGQRPLV
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEE
VGKPEPLMFQLALETLPMGATALVIGDRVDSDVLGAHRVGLPAVLLAREAPAFPARDLRR
EECCCCEEHHHHHHHCCCCCEEEEECCCCCCHHHCHHHCCCCHHHHCCCCCCCCHHHCCC
PERIATSLAELVATSPEIPPRPVDDVRWPERVVAGVILVVLDETIEMVALVPVASSWMLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WVALEPLESFADAAERLLARILPSQPVTLTFRPELVDGTVLVSDVDGALIQLAGPVVVVR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHEEECCCEEEEE
ITGSMLAGGAEWREIARARQLLPADQARVLESALSALD
EECCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRALDFDAWLLDLDGVVYVGDRLLPGVAEALATLRATGKHLRFLTNDPRPTREQLAERLR
CCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHH
RLGIDVAVEEVVTCGWATARLLPQLGIGSAYVVGSVGLAEELARVGITVVDDGIPDAVVV
HCCCHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEECCCCCEEEE
GADERLDFRRVVKGSLLVQRGARFVATNADASYPMPFGTVPATGAVVCAIRLATGQRPLV
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEE
VGKPEPLMFQLALETLPMGATALVIGDRVDSDVLGAHRVGLPAVLLAREAPAFPARDLRR
EECCCCEEHHHHHHHCCCCCEEEEECCCCCCHHHCHHHCCCCHHHHCCCCCCCCHHHCCC
PERIATSLAELVATSPEIPPRPVDDVRWPERVVAGVILVVLDETIEMVALVPVASSWMLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WVALEPLESFADAAERLLARILPSQPVTLTFRPELVDGTVLVSDVDGALIQLAGPVVVVR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHEEECCCEEEEE
ITGSMLAGGAEWREIARARQLLPADQARVLESALSALD
EECCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631946 [H]