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The map label for this gene is clpX [H]

Identifier: 221633184

GI number: 221633184

Start: 1189096

End: 1190367

Strand: Reverse

Name: clpX [H]

Synonym: trd_1201

Alternate gene names: 221633184

Gene position: 1190367-1189096 (Counterclockwise)

Preceding gene: 221633185

Following gene: 221633181

Centisome position: 59.43

GC content: 58.73

Gene sequence:

>1272_bases
ATGGGGATGACAACGCGTGGGGGACGGGTCTTTTATCGCTGTTCGTTCTGTGGCAAGAGCCAGGAGGAGGTGCGACGACT
CATCGCCGGCCCGAACGGGGTATACATCTGCGATGAATGTGTCCAGCTCTGCCAGGAGATCATTCAAGAAGAGGCACCGG
CGCGGCGCCCGGCTCCCGCTCCCACGCAGATCCCGACTCCCAAGCAGCTGTACGAGCAGCTGAACCAGTACGTCGTCGGC
CAAGAACGGGCGAAGAAGGTACTGTCGGTCGCTGTCTACAACCATTACAAGCGGATCATCTTCGGGGAAGACAGCGACGT
GGAGCTGCAGAAGAGCAATATCCTGCTCATCGGCCCGACTGGAAGTGGGAAGACGCTCTTGGCCCAAACGCTGGCCAAAT
TGCTCGACGTCCCGTTCTCCATTTCCGACGCGACGACACTCACCGAGGCCGGGTACGTGGGGGAGGACGTCGAGAATATC
CTTCTCCGTCTCATCCAGGCAGCGGGAGGCGATATCCAGCGAGCACAAACTGGAATCATCTACATCGACGAGATCGACAA
GATCGCTCGCAAGAGCGATAGTCCGTCGATCACTCGCGATGTTTCCGGAGAAGGGGTGCAGCAGGCGCTCCTGAAGATTC
TCGAAGGGACTATCGCCAACGTGCCTCCGCATGGTGGTCGCAAGCATCCCCATCAGGAGTACATTCAGATCGATACTCGC
AATATCCTCTTCATCTGCGGCGGAGCATTCGAAGGGCTTGACGAGATTGTCCGTCGGCGAATCGGTAAGGACTCGACGAT
CGGATTCGGGAAGAGCGCTCGGCAAGATGGACGCGTGGAGAATGTGTTGCACCAGGTCATCCCCGATGACCTCTTGAAGT
TCGGATTGATCCCCGAGTTCATCGGTCGCCTGCCAGTCGTCGCGGCGCTCGATCCTTTGACGCACGACGACCTAGTACGG
ATCTTGGTGGAGCCGAAAAACGCGATCGTCAAGCAGTATCAGAAGATCTTCGCGATGGACAACGTGGAGCTGATCTTTAC
CCCTGATGCGCTTCATGCAACCGCCGATCTCGCCGAGCGGCGTGGTACGGGCGCACGTGGCTTGCGGACGACCTTGGAGG
AGGTGTTGCTCGATGTCATGTACGAGCTTCCCTCGCTCCAGGGTGTTCGCAAGTGTGTCGTGACCGCCGATGTCATCTAC
CGACGTCGCCCACCGCTCCTCTTGGCGGCAAACGACGAACCGATCGAGTTCACCTACGAGCAGAGCGCCTGA

Upstream 100 bases:

>100_bases
TGAGCGCGTACGAGGCGAAGGACTACGGGATCGTGGATCACGTGCTCGAGCCGGTCAAACTCCAGCGAGCGTAGGCGAGC
CAACGGGTGGAGAAGGGGCG

Downstream 100 bases:

>100_bases
ACGCGACTGGACGAACGCCGCAAGGCCGGTCCCTCACCTGGGCCTCGCGGCATGCCTGCCTTCGCGAGCAGTGAGCGATT
CCGGGGTCTCATTCCTTCTT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MGMTTRGGRVFYRCSFCGKSQEEVRRLIAGPNGVYICDECVQLCQEIIQEEAPARRPAPAPTQIPTPKQLYEQLNQYVVG
QERAKKVLSVAVYNHYKRIIFGEDSDVELQKSNILLIGPTGSGKTLLAQTLAKLLDVPFSISDATTLTEAGYVGEDVENI
LLRLIQAAGGDIQRAQTGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKILEGTIANVPPHGGRKHPHQEYIQIDTR
NILFICGGAFEGLDEIVRRRIGKDSTIGFGKSARQDGRVENVLHQVIPDDLLKFGLIPEFIGRLPVVAALDPLTHDDLVR
ILVEPKNAIVKQYQKIFAMDNVELIFTPDALHATADLAERRGTGARGLRTTLEEVLLDVMYELPSLQGVRKCVVTADVIY
RRRPPLLLAANDEPIEFTYEQSA

Sequences:

>Translated_423_residues
MGMTTRGGRVFYRCSFCGKSQEEVRRLIAGPNGVYICDECVQLCQEIIQEEAPARRPAPAPTQIPTPKQLYEQLNQYVVG
QERAKKVLSVAVYNHYKRIIFGEDSDVELQKSNILLIGPTGSGKTLLAQTLAKLLDVPFSISDATTLTEAGYVGEDVENI
LLRLIQAAGGDIQRAQTGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKILEGTIANVPPHGGRKHPHQEYIQIDTR
NILFICGGAFEGLDEIVRRRIGKDSTIGFGKSARQDGRVENVLHQVIPDDLLKFGLIPEFIGRLPVVAALDPLTHDDLVR
ILVEPKNAIVKQYQKIFAMDNVELIFTPDALHATADLAERRGTGARGLRTTLEEVLLDVMYELPSLQGVRKCVVTADVIY
RRRPPLLLAANDEPIEFTYEQSA
>Mature_422_residues
GMTTRGGRVFYRCSFCGKSQEEVRRLIAGPNGVYICDECVQLCQEIIQEEAPARRPAPAPTQIPTPKQLYEQLNQYVVGQ
ERAKKVLSVAVYNHYKRIIFGEDSDVELQKSNILLIGPTGSGKTLLAQTLAKLLDVPFSISDATTLTEAGYVGEDVENIL
LRLIQAAGGDIQRAQTGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKILEGTIANVPPHGGRKHPHQEYIQIDTRN
ILFICGGAFEGLDEIVRRRIGKDSTIGFGKSARQDGRVENVLHQVIPDDLLKFGLIPEFIGRLPVVAALDPLTHDDLVRI
LVEPKNAIVKQYQKIFAMDNVELIFTPDALHATADLAERRGTGARGLRTTLEEVLLDVMYELPSLQGVRKCVVTADVIYR
RRPPLLLAANDEPIEFTYEQSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=49.1228070175439, Blast_Score=292, Evalue=5e-79,
Organism=Escherichia coli, GI1786642, Length=410, Percent_Identity=61.9512195121951, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=41.747572815534, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=411, Percent_Identity=38.4428223844282, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=334, Percent_Identity=43.1137724550898, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=404, Percent_Identity=37.1287128712871, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=39.5256916996047, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319704, Length=411, Percent_Identity=42.5790754257908, Blast_Score=275, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=47.6489028213166, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=47.6489028213166, Blast_Score=288, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46821; Mature: 46690

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMTTRGGRVFYRCSFCGKSQEEVRRLIAGPNGVYICDECVQLCQEIIQEEAPARRPAPA
CCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
PTQIPTPKQLYEQLNQYVVGQERAKKVLSVAVYNHYKRIIFGEDSDVELQKSNILLIGPT
CCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCEEEEECC
GSGKTLLAQTLAKLLDVPFSISDATTLTEAGYVGEDVENILLRLIQAAGGDIQRAQTGII
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKILEGTIANVPPHGGRKHPHQEYIQIDTR
EEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEECC
NILFICGGAFEGLDEIVRRRIGKDSTIGFGKSARQDGRVENVLHQVIPDDLLKFGLIPEF
EEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCHHHH
IGRLPVVAALDPLTHDDLVRILVEPKNAIVKQYQKIFAMDNVELIFTPDALHATADLAER
HCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
RGTGARGLRTTLEEVLLDVMYELPSLQGVRKCVVTADVIYRRRPPLLLAANDEPIEFTYE
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
QSA
CCC
>Mature Secondary Structure 
GMTTRGGRVFYRCSFCGKSQEEVRRLIAGPNGVYICDECVQLCQEIIQEEAPARRPAPA
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
PTQIPTPKQLYEQLNQYVVGQERAKKVLSVAVYNHYKRIIFGEDSDVELQKSNILLIGPT
CCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCEEEEECC
GSGKTLLAQTLAKLLDVPFSISDATTLTEAGYVGEDVENILLRLIQAAGGDIQRAQTGII
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKILEGTIANVPPHGGRKHPHQEYIQIDTR
EEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEECC
NILFICGGAFEGLDEIVRRRIGKDSTIGFGKSARQDGRVENVLHQVIPDDLLKFGLIPEF
EEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCHHHH
IGRLPVVAALDPLTHDDLVRILVEPKNAIVKQYQKIFAMDNVELIFTPDALHATADLAER
HCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
RGTGARGLRTTLEEVLLDVMYELPSLQGVRKCVVTADVIYRRRPPLLLAANDEPIEFTYE
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
QSA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]