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The map label for this gene is yedY [H]

Identifier: 221633136

GI number: 221633136

Start: 1140339

End: 1141796

Strand: Reverse

Name: yedY [H]

Synonym: trd_1152

Alternate gene names: 221633136

Gene position: 1141796-1140339 (Counterclockwise)

Preceding gene: 221633137

Following gene: 221633135

Centisome position: 57.0

GC content: 64.47

Gene sequence:

>1458_bases
ATGAACTCAGGTCAACGATTGGCGAGATTCGCCCCCGGAGCCGTCGTCGGCCTCCTCTGGGGAATCTTCCTGCTCCTCGT
GGAGTCGCTCGTCGGCGCCGCGACGCTGCTCCGAGCCGTTCTCGACGCGACCACGCGGATCCTTCCGGTCGGTCTTTTCG
GTTGGCTGCTCGGACGCGCCGAAAGTGCGGCGAAGCCGCTCGCCGTAGTGGGAACGCTCGCCATGTTCACCCTCGTCGCT
GGTGTGCTCACCCTCGTGCTGCGAGGACGTGCCCGCACCTGGTTGCTCGGAGCGCTCGCTCTCTTGCTGTGGTCCGGCAC
AGTATGGGTCGCGTACGAGTACGGTGAAGCGCTCACGACCGCCTTGTTCGTCGCGAGCAGCAGTACGTTCTTCCTCGTTG
GCGGATTGTGGATCGTTTCCGCTGAGGCGCAGCCGAGTTCGCGGACGCGGCGACGGTTGCTCCGCACCTTCCTCGGAGCA
GGCCTGGTGTTGGGACTGGCGACTGCTGGTCGGTTTCTCACCGGTTTGAGGGCACGATCGCGCGCCCCTCGAGCGGTCGA
CGAGCGTGGGCTTTCGCCCGCCATCACACCACTCGCTGATTTCTACGTCGTGTCCAAGAATGTCGCCGATCCGGAGGTCG
ATCTGGCTCGCTGGCGGCTGCGAGTCATTGGACGCGTCCGCCGACCCCTCGAGCTCGATCTCGCAGCCTTGCGGTCTCGT
CCAGCGGTGCGCATGGTTTCGACGCTCGAGTGCATCAGCAATGATGTCTGGGGACCGTACATCAGTACCGGCGAGTGGAT
CGGTCTGCGCTTGCGCGATCTTTTGTTGGAGGCGGAACCGGTGGACCCACTGGTCGATGTCGTCCTTCGAGCAGCCGATG
AGTACTCGGATTCCATTCCGTTTTCGGTCGCGTTGGACCCCGCGGTGCTCTTGGCCTACGGCCTCAATGGAGAGTCTCTC
CCGCGTGAACATGGGTTCCCACTGCGCCTGGTCGTGCCAGGTATTTACGGCATGAAGAATGTGAAGTGGATCACCGAGAT
CGAGCTGGTCGATTTCGACTACCTCGGGTACTGGCAGCAACGCGGGTGGAGCGACAGTGCGATCGTCCAGATCCACTCGC
GCATCGACACGCCTCGGGGTGGGAGCGTTCTGACAGTCGGGCAGGAGGTCCTCGTCGGTGGTATCGCCTTCGCGGGAACG
CGCGGGATCCAGCGTGTCGAGGTGTCGGTCGATGGAGGAGCTACCTGGCGACCGGCCGAGATGGAGAGCCCGCTCTCACC
GTATTCCTGGGTGCGCTGGTGGATCACCTGGCGTCCGGACCAAGAAGGACGTGCTCGCCTGGTGGTGCGCGCCTGGGACG
GTGACGGTCGGCTCCAGGAAGAGCGGGAGCGACCACCGCTCCCCGATGGAGCGACTGGTTGGCATCGCATCACCGTTGAC
GTGCGCGCGCGGACCTGA

Upstream 100 bases:

>100_bases
CGGAAACGAGCGAAGCTGAGATCGTGCGCCAGCGGCTCGACCGATTCGATGCCGCTTCCTTCGTTAGCCAGCTGCGGGCG
TACGAGACTGGGCGGGCGCG

Downstream 100 bases:

>100_bases
GCGCGAAGCAGAGGAGCAGGCGAGGTGAACGACGAAGCCTTTCGATTGGTTCCTATTGGGGTCGTCCACTCACCGGTCGC
TGATCGGCGTCTCATGCCTC

Product: nitrate reductase (NAD(P)H)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNSGQRLARFAPGAVVGLLWGIFLLLVESLVGAATLLRAVLDATTRILPVGLFGWLLGRAESAAKPLAVVGTLAMFTLVA
GVLTLVLRGRARTWLLGALALLLWSGTVWVAYEYGEALTTALFVASSSTFFLVGGLWIVSAEAQPSSRTRRRLLRTFLGA
GLVLGLATAGRFLTGLRARSRAPRAVDERGLSPAITPLADFYVVSKNVADPEVDLARWRLRVIGRVRRPLELDLAALRSR
PAVRMVSTLECISNDVWGPYISTGEWIGLRLRDLLLEAEPVDPLVDVVLRAADEYSDSIPFSVALDPAVLLAYGLNGESL
PREHGFPLRLVVPGIYGMKNVKWITEIELVDFDYLGYWQQRGWSDSAIVQIHSRIDTPRGGSVLTVGQEVLVGGIAFAGT
RGIQRVEVSVDGGATWRPAEMESPLSPYSWVRWWITWRPDQEGRARLVVRAWDGDGRLQEERERPPLPDGATGWHRITVD
VRART

Sequences:

>Translated_485_residues
MNSGQRLARFAPGAVVGLLWGIFLLLVESLVGAATLLRAVLDATTRILPVGLFGWLLGRAESAAKPLAVVGTLAMFTLVA
GVLTLVLRGRARTWLLGALALLLWSGTVWVAYEYGEALTTALFVASSSTFFLVGGLWIVSAEAQPSSRTRRRLLRTFLGA
GLVLGLATAGRFLTGLRARSRAPRAVDERGLSPAITPLADFYVVSKNVADPEVDLARWRLRVIGRVRRPLELDLAALRSR
PAVRMVSTLECISNDVWGPYISTGEWIGLRLRDLLLEAEPVDPLVDVVLRAADEYSDSIPFSVALDPAVLLAYGLNGESL
PREHGFPLRLVVPGIYGMKNVKWITEIELVDFDYLGYWQQRGWSDSAIVQIHSRIDTPRGGSVLTVGQEVLVGGIAFAGT
RGIQRVEVSVDGGATWRPAEMESPLSPYSWVRWWITWRPDQEGRARLVVRAWDGDGRLQEERERPPLPDGATGWHRITVD
VRART
>Mature_485_residues
MNSGQRLARFAPGAVVGLLWGIFLLLVESLVGAATLLRAVLDATTRILPVGLFGWLLGRAESAAKPLAVVGTLAMFTLVA
GVLTLVLRGRARTWLLGALALLLWSGTVWVAYEYGEALTTALFVASSSTFFLVGGLWIVSAEAQPSSRTRRRLLRTFLGA
GLVLGLATAGRFLTGLRARSRAPRAVDERGLSPAITPLADFYVVSKNVADPEVDLARWRLRVIGRVRRPLELDLAALRSR
PAVRMVSTLECISNDVWGPYISTGEWIGLRLRDLLLEAEPVDPLVDVVLRAADEYSDSIPFSVALDPAVLLAYGLNGESL
PREHGFPLRLVVPGIYGMKNVKWITEIELVDFDYLGYWQQRGWSDSAIVQIHSRIDTPRGGSVLTVGQEVLVGGIAFAGT
RGIQRVEVSVDGGATWRPAEMESPLSPYSWVRWWITWRPDQEGRARLVVRAWDGDGRLQEERERPPLPDGATGWHRITVD
VRART

Specific function: The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase

COG id: COG2041

COG function: function code R; Sulfite oxidase and related enzymes

Gene ontology:

Cell location: Periplasm. Note=Is attached to the inner membrane when interacting with the yedZ subunit (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yedY family [H]

Homologues:

Organism=Homo sapiens, GI74099704, Length=347, Percent_Identity=31.700288184438, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI74099702, Length=347, Percent_Identity=31.700288184438, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI74099694, Length=347, Percent_Identity=31.700288184438, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI1788282, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992535, Length=268, Percent_Identity=30.5970149253731, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859905, Length=287, Percent_Identity=31.0104529616725, Blast_Score=105, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000572
- InterPro:   IPR006311
- InterPro:   IPR022867 [H]

Pfam domain/function: PF00174 Oxidored_molyb [H]

EC number: NA

Molecular weight: Translated: 53270; Mature: 53270

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGQRLARFAPGAVVGLLWGIFLLLVESLVGAATLLRAVLDATTRILPVGLFGWLLGRA
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAAKPLAVVGTLAMFTLVAGVLTLVLRGRARTWLLGALALLLWSGTVWVAYEYGEALTT
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
ALFVASSSTFFLVGGLWIVSAEAQPSSRTRRRLLRTFLGAGLVLGLATAGRFLTGLRARS
HHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RAPRAVDERGLSPAITPLADFYVVSKNVADPEVDLARWRLRVIGRVRRPLELDLAALRSR
CCCCCHHHCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC
PAVRMVSTLECISNDVWGPYISTGEWIGLRLRDLLLEAEPVDPLVDVVLRAADEYSDSIP
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
FSVALDPAVLLAYGLNGESLPREHGFPLRLVVPGIYGMKNVKWITEIELVDFDYLGYWQQ
EEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHH
RGWSDSAIVQIHSRIDTPRGGSVLTVGQEVLVGGIAFAGTRGIQRVEVSVDGGATWRPAE
CCCCCHHHEEEEHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
MESPLSPYSWVRWWITWRPDQEGRARLVVRAWDGDGRLQEERERPPLPDGATGWHRITVD
CCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCEEEEEE
VRART
EEECC
>Mature Secondary Structure
MNSGQRLARFAPGAVVGLLWGIFLLLVESLVGAATLLRAVLDATTRILPVGLFGWLLGRA
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAAKPLAVVGTLAMFTLVAGVLTLVLRGRARTWLLGALALLLWSGTVWVAYEYGEALTT
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
ALFVASSSTFFLVGGLWIVSAEAQPSSRTRRRLLRTFLGAGLVLGLATAGRFLTGLRARS
HHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RAPRAVDERGLSPAITPLADFYVVSKNVADPEVDLARWRLRVIGRVRRPLELDLAALRSR
CCCCCHHHCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC
PAVRMVSTLECISNDVWGPYISTGEWIGLRLRDLLLEAEPVDPLVDVVLRAADEYSDSIP
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
FSVALDPAVLLAYGLNGESLPREHGFPLRLVVPGIYGMKNVKWITEIELVDFDYLGYWQQ
EEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHH
RGWSDSAIVQIHSRIDTPRGGSVLTVGQEVLVGGIAFAGTRGIQRVEVSVDGGATWRPAE
CCCCCHHHEEEEHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
MESPLSPYSWVRWWITWRPDQEGRARLVVRAWDGDGRLQEERERPPLPDGATGWHRITVD
CCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCEEEEEE
VRART
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]