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The map label for this gene is oxaA [H]

Identifier: 221633069

GI number: 221633069

Start: 1057912

End: 1058850

Strand: Reverse

Name: oxaA [H]

Synonym: trd_1085

Alternate gene names: 221633069

Gene position: 1058850-1057912 (Counterclockwise)

Preceding gene: 221633070

Following gene: 221633068

Centisome position: 52.86

GC content: 59.74

Gene sequence:

>939_bases
TTGATCATTTGGGATCAGTTCGTCTATGCCATCGAGTGGGGACTGGCCCGCACTGCCGAGGTGACGGGTAGCGCTGGACT
GGCGATCATCCTCTTCACGATTCTCATCAAGACACTTCTGTTGCCTCTTACCATCAAATCGGTGCGGTCTACCAAGGCGA
TGCAGGAACTGCAGCCGAAGATTCGGGAACTGCAGAAGAAATACGGCCAGGATCGTCAGCGTCTCTCGGCAGAGATGATG
AAGCTGTACCAGGAGCATGGGATCAATCCGATGTCGGGATGTCTCCCGATGCTCCTCCAGATACCTGTCTTCTTCGGCCT
GTACTTCGCGATCCGCAATCTGTCGCTCAGCCAGGTTGGGGCCTGGGCGCACGGTTTCCTCTGGATTCCGGATCTTGCGA
AACCGGATCCTCTGCACATCTTGCCGATTTTGGCTGGTCTTTTCCAGTTCATCCAGACTCGGATGACGCGTCCAGCCGGT
GTGCGGCGGTTCGAGGATCCGCAGCAGCAAATGATGTACTCGATGATGCTCTTCATGCCGTTGATGGTCGTTCTGTTCGG
CTGGAACTTTGCAGCCGGCCCCGTTCTGTATTGGGTCGTCTCGGCAGTCTACAGCGTGGTGCAGCAGTGGTTGATCACTG
GGTGGGGTGCGATGCGCGATTGGCTGCCGTTCCTGCCCGAGTTGCCGGAGCACCGGCGGTTGGGGTATGTCGACCCCAAA
AAGCGAGCGAACAGCACGAATGCCAAGCGAGGCGGGTTGTGGGCGCGGTTCCTCGAACATGCGCAAGCACAGTCCCAGAT
CTCGGTGTCCGAGACGGCCGTCGAGTCGAGTCGCACCGAGCGTGCGGCGGCTGACGCCTCGCCTGCTTCCCAGCCTCCGG
TCGATCCCGCATCGCTCGTGCCGCGTCGCTCGCGACCGCGGAACAAGCGGCAGTCTTGA

Upstream 100 bases:

>100_bases
GGCGTCTGCTCCGCTGTCATCCTTTCCACCCAGGCGGGTACGATCCCGTGCCGTGACGGATTCACTGCACGAGAAGGCCT
GAGACGTCCAGGAGGTCGAC

Downstream 100 bases:

>100_bases
CCGCGCCGCTCCTTCACCCGGGTGTGATGGGGCAGGAGCGAGATGATGACAGAAAAGCGAGCTGTCGAGATCCAGGCTCG
ATCAGTCGATGAGGCAGTCC

Product: inner membrane protein oxaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIIWDQFVYAIEWGLARTAEVTGSAGLAIILFTILIKTLLLPLTIKSVRSTKAMQELQPKIRELQKKYGQDRQRLSAEMM
KLYQEHGINPMSGCLPMLLQIPVFFGLYFAIRNLSLSQVGAWAHGFLWIPDLAKPDPLHILPILAGLFQFIQTRMTRPAG
VRRFEDPQQQMMYSMMLFMPLMVVLFGWNFAAGPVLYWVVSAVYSVVQQWLITGWGAMRDWLPFLPELPEHRRLGYVDPK
KRANSTNAKRGGLWARFLEHAQAQSQISVSETAVESSRTERAAADASPASQPPVDPASLVPRRSRPRNKRQS

Sequences:

>Translated_312_residues
MIIWDQFVYAIEWGLARTAEVTGSAGLAIILFTILIKTLLLPLTIKSVRSTKAMQELQPKIRELQKKYGQDRQRLSAEMM
KLYQEHGINPMSGCLPMLLQIPVFFGLYFAIRNLSLSQVGAWAHGFLWIPDLAKPDPLHILPILAGLFQFIQTRMTRPAG
VRRFEDPQQQMMYSMMLFMPLMVVLFGWNFAAGPVLYWVVSAVYSVVQQWLITGWGAMRDWLPFLPELPEHRRLGYVDPK
KRANSTNAKRGGLWARFLEHAQAQSQISVSETAVESSRTERAAADASPASQPPVDPASLVPRRSRPRNKRQS
>Mature_312_residues
MIIWDQFVYAIEWGLARTAEVTGSAGLAIILFTILIKTLLLPLTIKSVRSTKAMQELQPKIRELQKKYGQDRQRLSAEMM
KLYQEHGINPMSGCLPMLLQIPVFFGLYFAIRNLSLSQVGAWAHGFLWIPDLAKPDPLHILPILAGLFQFIQTRMTRPAG
VRRFEDPQQQMMYSMMLFMPLMVVLFGWNFAAGPVLYWVVSAVYSVVQQWLITGWGAMRDWLPFLPELPEHRRLGYVDPK
KRANSTNAKRGGLWARFLEHAQAQSQISVSETAVESSRTERAAADASPASQPPVDPASLVPRRSRPRNKRQS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=191, Percent_Identity=39.7905759162304, Blast_Score=137, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321002, Length=186, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24662345, Length=189, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356443, Length=189, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 35450; Mature: 35450

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWDQFVYAIEWGLARTAEVTGSAGLAIILFTILIKTLLLPLTIKSVRSTKAMQELQPK
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRELQKKYGQDRQRLSAEMMKLYQEHGINPMSGCLPMLLQIPVFFGLYFAIRNLSLSQVG
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AWAHGFLWIPDLAKPDPLHILPILAGLFQFIQTRMTRPAGVRRFEDPQQQMMYSMMLFMP
HHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LMVVLFGWNFAAGPVLYWVVSAVYSVVQQWLITGWGAMRDWLPFLPELPEHRRLGYVDPK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KRANSTNAKRGGLWARFLEHAQAQSQISVSETAVESSRTERAAADASPASQPPVDPASLV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
PRRSRPRNKRQS
CCCCCCCCCCCC
>Mature Secondary Structure
MIIWDQFVYAIEWGLARTAEVTGSAGLAIILFTILIKTLLLPLTIKSVRSTKAMQELQPK
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRELQKKYGQDRQRLSAEMMKLYQEHGINPMSGCLPMLLQIPVFFGLYFAIRNLSLSQVG
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AWAHGFLWIPDLAKPDPLHILPILAGLFQFIQTRMTRPAGVRRFEDPQQQMMYSMMLFMP
HHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LMVVLFGWNFAAGPVLYWVVSAVYSVVQQWLITGWGAMRDWLPFLPELPEHRRLGYVDPK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KRANSTNAKRGGLWARFLEHAQAQSQISVSETAVESSRTERAAADASPASQPPVDPASLV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
PRRSRPRNKRQS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA