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The map label for this gene is ygjG [C]

Identifier: 221633064

GI number: 221633064

Start: 1053623

End: 1054978

Strand: Reverse

Name: ygjG [C]

Synonym: trd_1080

Alternate gene names: 221633064

Gene position: 1054978-1053623 (Counterclockwise)

Preceding gene: 221633067

Following gene: 221633063

Centisome position: 52.67

GC content: 62.17

Gene sequence:

>1356_bases
ATGCAAGTCGAGACCTGGAACGCCGCGGAGCTGGTGGCCAAGGATATCGCACACCATCTTCACCCGTTGACCAATCTGTA
CCAGCTCCGGCGGGAGGGACCGCTCGTCCTCGTTCGTGGAGAGGGGGTTTGGGTCTGGGATGCTGAGGGGAAGCGTTACC
TCGATGGATTCGCGGGATTGTGGAACGTGAACATCGGGCACGGTCGGCGCGAGTTGGCTGAAGCGGCTCGCGAGCAGATG
GAGCGGGTCGCCTTCGTGCCGACATTCTTCGGACTAGCTAGTCCGCCGACGATCGAGCTGGCGGCGCGCTTGGCCGAGCT
CTTTCCTGGACCACTCGATCATTTCCAGTTCACGTCGGGCGGTGCCGAGTCGAACGAGACGGCGATCAAGATCGCCCGGT
ATTACTGGTGGCTCAAGGGACAGCCTGAAAGGGTGAAGATTTTGTCGCGTCGGATGGCCTATCACGGCATCGCCATGGGA
GCATTGTCGGCGACCGGCGTGCCCGCGTACTGGGAAGGGTTCGGACCGCGCCCACCGGGGTTCATCCACCTCACCGCACC
GTACAAGTACCGTTTCGGGGAAGGGCTCACCGACGAGGAGTTCGTCGCTCGGTTGGTCCAGGAACTGGAAGAAACGATCG
AGCGAGAGGGATCGGAGACGATCGCGGCTTTCATCGGTGAGCCGGTTCAAGGTGCAGGCGGTGTCGTCGTTCCACCTGAC
GGCTACTGGCCGGCCATCGCTGCAGTGTTGCGCAAGTACGGAATTCTCCTGATATTGGACGAGGTGATTACCGGGTTCGG
GCGGACTGGCACGCTGTTCGGTATGCAGCAATATGGGGTCCAGCCGGATATCGTGACGTTCGCCAAGGGAATCACTTCCG
GTTATGTGCCGCTGGGTGGCGTCGGCGTCAGCGATGAGATCGCTGAAACCTTAGCGAGTGCTGACCGTGTCTTCATGCAC
GGGTTCACCTACTCTGGGCATCCGGTCGCGTGCGCGGTCGCGCTGCGCAATCTCGACATTCTTCTGGCGGAAAGACTGTG
GGAGAACGCCGCGGCGTCCGGTGCATACCTGCTCCAGGAACTCAAGCGGCTGGAGGAGCGACCGTACGTCGGTGAGGTTC
GCGGCAAGGGTCTCATGCTGCTCGTCGAGGTCGTTCGGGACAAAGCGAGCAAGGAAAAGTTCCCGCCCGAGTTCAAACTG
GGGCCGAAGCTGGAGGCGGCGACGCGCCGTCGCGGCATCATCGTGCGCTGCACGCCGGACGGTATCGTGATGGCACCGCC
GCTGACCATTTCGCGAGCCGAATGTGACGTCCTCATCGAAGGAGTCGCGGCAGCCCTGAGCGATGTGCTCGACTGA

Upstream 100 bases:

>100_bases
TGGTCGGCTGTGGGGGAACACTGCACTGTGCACTGGACACTGGGCGCTCGACTCGGGAACAATGGTGAGGGTTCGCACTG
GAGGCGAGGAGGGCAACACG

Downstream 100 bases:

>100_bases
CGACAGCTGAGGCTTCGAGTTCTGCTGACTCTGCTCGACCCCGGGCCGGCGGAAGGCCGTGACGGCTTTGCTACCCTGGT
TCACGATTGCGGCGGTACCT

Product: aminotransferase, class III

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQVETWNAAELVAKDIAHHLHPLTNLYQLRREGPLVLVRGEGVWVWDAEGKRYLDGFAGLWNVNIGHGRRELAEAAREQM
ERVAFVPTFFGLASPPTIELAARLAELFPGPLDHFQFTSGGAESNETAIKIARYYWWLKGQPERVKILSRRMAYHGIAMG
ALSATGVPAYWEGFGPRPPGFIHLTAPYKYRFGEGLTDEEFVARLVQELEETIEREGSETIAAFIGEPVQGAGGVVVPPD
GYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITSGYVPLGGVGVSDEIAETLASADRVFMH
GFTYSGHPVACAVALRNLDILLAERLWENAAASGAYLLQELKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKL
GPKLEAATRRRGIIVRCTPDGIVMAPPLTISRAECDVLIEGVAAALSDVLD

Sequences:

>Translated_451_residues
MQVETWNAAELVAKDIAHHLHPLTNLYQLRREGPLVLVRGEGVWVWDAEGKRYLDGFAGLWNVNIGHGRRELAEAAREQM
ERVAFVPTFFGLASPPTIELAARLAELFPGPLDHFQFTSGGAESNETAIKIARYYWWLKGQPERVKILSRRMAYHGIAMG
ALSATGVPAYWEGFGPRPPGFIHLTAPYKYRFGEGLTDEEFVARLVQELEETIEREGSETIAAFIGEPVQGAGGVVVPPD
GYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITSGYVPLGGVGVSDEIAETLASADRVFMH
GFTYSGHPVACAVALRNLDILLAERLWENAAASGAYLLQELKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKL
GPKLEAATRRRGIIVRCTPDGIVMAPPLTISRAECDVLIEGVAAALSDVLD
>Mature_451_residues
MQVETWNAAELVAKDIAHHLHPLTNLYQLRREGPLVLVRGEGVWVWDAEGKRYLDGFAGLWNVNIGHGRRELAEAAREQM
ERVAFVPTFFGLASPPTIELAARLAELFPGPLDHFQFTSGGAESNETAIKIARYYWWLKGQPERVKILSRRMAYHGIAMG
ALSATGVPAYWEGFGPRPPGFIHLTAPYKYRFGEGLTDEEFVARLVQELEETIEREGSETIAAFIGEPVQGAGGVVVPPD
GYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITSGYVPLGGVGVSDEIAETLASADRVFMH
GFTYSGHPVACAVALRNLDILLAERLWENAAASGAYLLQELKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKL
GPKLEAATRRRGIIVRCTPDGIVMAPPLTISRAECDVLIEGVAAALSDVLD

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=455, Percent_Identity=33.1868131868132, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=31.1475409836066, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI37574042, Length=361, Percent_Identity=31.8559556786704, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI226442705, Length=361, Percent_Identity=31.8559556786704, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=28.0182232346241, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI226442709, Length=330, Percent_Identity=32.1212121212121, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI284507298, Length=323, Percent_Identity=32.8173374613003, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI188536080, Length=441, Percent_Identity=24.7165532879819, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38679950, Length=441, Percent_Identity=24.7165532879819, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38679946, Length=441, Percent_Identity=24.7165532879819, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI145693181, Length=403, Percent_Identity=33.2506203473945, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=32.9238329238329, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1789759, Length=419, Percent_Identity=28.8782816229117, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=31.4903846153846, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1786991, Length=448, Percent_Identity=30.5803571428571, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=32.2115384615385, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=30.6188925081433, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=438, Percent_Identity=31.5068493150685, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=30, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=414, Percent_Identity=28.9855072463768, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=27.2935779816514, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=395, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=438, Percent_Identity=31.2785388127854, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324432, Length=365, Percent_Identity=28.4931506849315, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=399, Percent_Identity=28.3208020050125, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321456, Length=445, Percent_Identity=23.5955056179775, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=33.6909871244635, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI21357415, Length=421, Percent_Identity=33.0166270783848, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161085790, Length=462, Percent_Identity=33.7662337662338, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=30.4147465437788, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281366494, Length=383, Percent_Identity=24.2819843342037, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667139, Length=383, Percent_Identity=24.2819843342037, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667143, Length=383, Percent_Identity=24.2819843342037, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49469; Mature: 49469

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVETWNAAELVAKDIAHHLHPLTNLYQLRREGPLVLVRGEGVWVWDAEGKRYLDGFAGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHCCE
WNVNIGHGRRELAEAAREQMERVAFVPTFFGLASPPTIELAARLAELFPGPLDHFQFTSG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEECCC
GAESNETAIKIARYYWWLKGQPERVKILSRRMAYHGIAMGALSATGVPAYWEGFGPRPPG
CCCCCCHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCC
FIHLTAPYKYRFGEGLTDEEFVARLVQELEETIEREGSETIAAFIGEPVQGAGGVVVPPD
EEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEECCC
GYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITSGYVPLGG
CCHHHHHHHHHHCCHHEEHHHHHHCCCCCCEEECHHHHCCCCCHHHHHHHHCCCCCCCCC
VGVSDEIAETLASADRVFMHGFTYSGHPVACAVALRNLDILLAERLWENAAASGAYLLQE
CCCCHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKLGPKLEAATRRRGIIVRCTPD
HHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEEEECCC
GIVMAPPLTISRAECDVLIEGVAAALSDVLD
CEEECCCCEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVETWNAAELVAKDIAHHLHPLTNLYQLRREGPLVLVRGEGVWVWDAEGKRYLDGFAGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHCCE
WNVNIGHGRRELAEAAREQMERVAFVPTFFGLASPPTIELAARLAELFPGPLDHFQFTSG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEECCC
GAESNETAIKIARYYWWLKGQPERVKILSRRMAYHGIAMGALSATGVPAYWEGFGPRPPG
CCCCCCHHEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCC
FIHLTAPYKYRFGEGLTDEEFVARLVQELEETIEREGSETIAAFIGEPVQGAGGVVVPPD
EEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEECCC
GYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITSGYVPLGG
CCHHHHHHHHHHCCHHEEHHHHHHCCCCCCEEECHHHHCCCCCHHHHHHHHCCCCCCCCC
VGVSDEIAETLASADRVFMHGFTYSGHPVACAVALRNLDILLAERLWENAAASGAYLLQE
CCCCHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKLGPKLEAATRRRGIIVRCTPD
HHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEEEECCC
GIVMAPPLTISRAECDVLIEGVAAALSDVLD
CEEECCCCEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]