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The map label for this gene is moaC

Identifier: 221633063

GI number: 221633063

Start: 1052753

End: 1053253

Strand: Reverse

Name: moaC

Synonym: trd_1078

Alternate gene names: 221633063

Gene position: 1053253-1052753 (Counterclockwise)

Preceding gene: 221633064

Following gene: 221633060

Centisome position: 52.58

GC content: 66.87

Gene sequence:

>501_bases
ATGGCCGAACTGACCCACCTCGACGAACGCGGCCAGGCCCGAATGGTGGACGTGGCGGAGAAGCCGGAGACGCACCGTGT
TGCCGTGGCGCGGGGCCGCGTCTCGCTGCGTCCGGAAACGCTTCAGCTCGTCCGGGAGGGACGGGCCGCTAAGGGTGACG
TGCTCGCTGTCGCTCGAGTGGCCGGCATCATGGCGGCCAAGCGCACTGCTGAGTTGATTCCGCTCTGTCATCCGCTTCCG
TTGACGAAGGTCGAAGTAGACGTGCGGACGAACGAGCAGGACACGTGCCTGGAGATCGAGGCGCGAGTCGAAACCGTGAG
TCGAACCGGCGTCGAGATGGAGGCCCTGACCGCGGTTGCCGTGGCAGCGCTGACGGTCTACGACATGCTGAAGGCGGTCG
ACCGGGGTATGACGATCGACCGTATCCAGCTGATCGAGAAGGCTGGGGGACGGAGCGGGACCTGGCGGCGCGAGGACGAC
GAGGCTCGTCACGCGCGCTGA

Upstream 100 bases:

>100_bases
CTGAACGTCGGCACGATCGACTGGCGCGGAGGGTATGCCAGCCAGAGCAGTCCCGGTCGCGAGCATCATTGCTCGTTCGA
CGCGCACAAGGAGGTCAGCG

Downstream 100 bases:

>100_bases
GCGAGAGCGGGGATCGGGCTCTCCTGCTCGGTTCGCACGACTTCCTCGGCGATGCCACCACCGACGACTCGGTCGCCGAC
ATAGAGGACGACCGACTGGC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAELTHLDERGQARMVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARVAGIMAAKRTAELIPLCHPLP
LTKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVAVAALTVYDMLKAVDRGMTIDRIQLIEKAGGRSGTWRREDD
EARHAR

Sequences:

>Translated_166_residues
MAELTHLDERGQARMVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARVAGIMAAKRTAELIPLCHPLP
LTKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVAVAALTVYDMLKAVDRGMTIDRIQLIEKAGGRSGTWRREDD
EARHAR
>Mature_165_residues
AELTHLDERGQARMVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARVAGIMAAKRTAELIPLCHPLPL
TKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVAVAALTVYDMLKAVDRGMTIDRIQLIEKAGGRSGTWRREDDE
ARHAR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=161, Percent_Identity=52.1739130434783, Blast_Score=165, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=50, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=50.6944444444444, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_THERP (B9L0K8)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002522288.1
- GeneID:   7356404
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1078
- OMA:   PMCHPLM
- ProtClustDB:   CLSK2807841
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 18301; Mature: 18170

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTHLDERGQARMVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARV
CCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCHHHHHHHH
AGIMAAKRTAELIPLCHPLPLTKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVA
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHHHHH
VAALTVYDMLKAVDRGMTIDRIQLIEKAGGRSGTWRREDDEARHAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AELTHLDERGQARMVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARV
CCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCHHHHHHHH
AGIMAAKRTAELIPLCHPLPLTKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVA
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHHHHH
VAALTVYDMLKAVDRGMTIDRIQLIEKAGGRSGTWRREDDEARHAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA