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The map label for this gene is moaB [H]

Identifier: 221633029

GI number: 221633029

Start: 1014607

End: 1015113

Strand: Reverse

Name: moaB [H]

Synonym: trd_1044

Alternate gene names: 221633029

Gene position: 1015113-1014607 (Counterclockwise)

Preceding gene: 221633030

Following gene: 221633028

Centisome position: 50.68

GC content: 62.52

Gene sequence:

>507_bases
GTGAGCAGCATCGAACAGCATCGGATGGCAGCACCGCGCAGCGTTCGTTGCGCGGTCGTGACCGTCAGCGACACGCGAAC
GGTCGAGACGGATACGAGCGGCGCGCTGATTCGTGAGCGATTGGAGCGCGCTGGGCATGCGGTCGTCTTCTATGCCATCG
TTCCGGACGAGCGGGAGGAGATCGGCCGGCTAGTCGATGAGTTGGTGCAGCGACCAGACTGCGATGCCGTTCTTCTCAAT
GGTGGTACTGGGATCGCGCGGCGCGATGTGACCTACGAGGCTATCGCGGAACGGATCGAGAAGCGCCTCGACGGCTTCGG
TGAGCTCTTCCGCTGGTTGAGCTATCGAGAGATCGGAACTGCCGCGATGCTCTCGCGAGCACTTGCCGGAGTCTATCGTG
GCCGGATCGTCATCGCCATGCCAGGCTCGACCGGTGCTGTGCGATTGGCCATGGATGAACTCGTTCTTCCCGAACTCGCG
CACCTCGTCTTCGAGGCACGCAAGTGA

Upstream 100 bases:

>100_bases
CGCACACGGTCGACGACAGCATTCGCCTGGCCGATCTGGAAGCAGCGATGGTGGGGTATGCTGCTCTAGCACTGACCTTG
ACGCGCGGGGAGGAGCATGC

Downstream 100 bases:

>100_bases
GAAAGAGGTCGGTAACGATGGGCGACGCAGCAGTACGGCGACCACCGCAAGTGCTGCGGGGAATGCGCGACTTCACTCCG
CGGCAGATGCTTCTGCGGCA

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSSIEQHRMAAPRSVRCAVVTVSDTRTVETDTSGALIRERLERAGHAVVFYAIVPDEREEIGRLVDELVQRPDCDAVLLN
GGTGIARRDVTYEAIAERIEKRLDGFGELFRWLSYREIGTAAMLSRALAGVYRGRIVIAMPGSTGAVRLAMDELVLPELA
HLVFEARK

Sequences:

>Translated_168_residues
MSSIEQHRMAAPRSVRCAVVTVSDTRTVETDTSGALIRERLERAGHAVVFYAIVPDEREEIGRLVDELVQRPDCDAVLLN
GGTGIARRDVTYEAIAERIEKRLDGFGELFRWLSYREIGTAAMLSRALAGVYRGRIVIAMPGSTGAVRLAMDELVLPELA
HLVFEARK
>Mature_167_residues
SSIEQHRMAAPRSVRCAVVTVSDTRTVETDTSGALIRERLERAGHAVVFYAIVPDEREEIGRLVDELVQRPDCDAVLLNG
GTGIARRDVTYEAIAERIEKRLDGFGELFRWLSYREIGTAAMLSRALAGVYRGRIVIAMPGSTGAVRLAMDELVLPELAH
LVFEARK

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=156, Percent_Identity=32.0512820512821, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI66932975, Length=156, Percent_Identity=32.0512820512821, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=42.7586206896552, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1786190, Length=100, Percent_Identity=34, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=155, Percent_Identity=36.7741935483871, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17136978, Length=155, Percent_Identity=33.5483870967742, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24638841, Length=155, Percent_Identity=33.5483870967742, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18611; Mature: 18479

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIEQHRMAAPRSVRCAVVTVSDTRTVETDTSGALIRERLERAGHAVVFYAIVPDEREE
CCCHHHHHHCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHHH
IGRLVDELVQRPDCDAVLLNGGTGIARRDVTYEAIAERIEKRLDGFGELFRWLSYREIGT
HHHHHHHHHCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMLSRALAGVYRGRIVIAMPGSTGAVRLAMDELVLPELAHLVFEARK
HHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSIEQHRMAAPRSVRCAVVTVSDTRTVETDTSGALIRERLERAGHAVVFYAIVPDEREE
CCHHHHHHCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHHH
IGRLVDELVQRPDCDAVLLNGGTGIARRDVTYEAIAERIEKRLDGFGELFRWLSYREIGT
HHHHHHHHHCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMLSRALAGVYRGRIVIAMPGSTGAVRLAMDELVLPELAHLVFEARK
HHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]