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The map label for this gene is lspA [H]

Identifier: 221633018

GI number: 221633018

Start: 998584

End: 999093

Strand: Reverse

Name: lspA [H]

Synonym: trd_1033

Alternate gene names: 221633018

Gene position: 999093-998584 (Counterclockwise)

Preceding gene: 221633019

Following gene: 221633017

Centisome position: 49.88

GC content: 56.86

Gene sequence:

>510_bases
GTGCGTGGATGGGAAATCGTCGCCTGTGTGGCGGCGATCGTTCTGGTCGTTGATCAGCTGAGCAAGGCGCTCGTGCTCAC
CTTTTTGGCTCCTGGTGCACCTCATGCGGAGGTCGTGATCGTCCCTGGATTCCTGCGGCTTTATTATGTTGAAAACACCG
GAGCAGCGTTTGGACTCTTTCAGGGGAAGAACCCATTGCTCGCTTTTCTCGCTTTCGGTGTCGTCGTTGCGCTCGTCGTC
TGGTTTCGGGAACTGGTGCGGTTCTGGCTCGGTGCACTGGCTCTGGGGTTACAGTTAGGCGGGGCGGTGGGCAATTTGAT
CGACCGGTTTCGTCATGGTTTCGTCGTCGATTTCATCGATTTCTCGTTTTGGCCGACGTTCAACTTGGCTGATAGTGCGA
TCACGATCGGCGTTCTCATGCTGCTGTACGTGCTCCTGCGCCAAGGGCAACTGGAGTCGCCGAGAGCAAGGGAAGCAGAG
AGGATCGACGCGGAGCAGCAGATTCGATGA

Upstream 100 bases:

>100_bases
GACGGACAGGCGAACAGCGGCCGAGCTGAGGGTAGAATTCCAAAGACACACGAGGGCATGAGCCGGAGCTGAACGGGCTC
TGCCGGAAGGAGCTGTGCCA

Downstream 100 bases:

>100_bases
CGGTTGGATCACGCGAAGCCATTCGACTCGTTCTCCAAATCTCCGAGCGGGAACATGGCGAGCGACTGGACAAGTTGATC
GCCAGTCGCGTGACCGGTAT

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRGWEIVACVAAIVLVVDQLSKALVLTFLAPGAPHAEVVIVPGFLRLYYVENTGAAFGLFQGKNPLLAFLAFGVVVALVV
WFRELVRFWLGALALGLQLGGAVGNLIDRFRHGFVVDFIDFSFWPTFNLADSAITIGVLMLLYVLLRQGQLESPRAREAE
RIDAEQQIR

Sequences:

>Translated_169_residues
MRGWEIVACVAAIVLVVDQLSKALVLTFLAPGAPHAEVVIVPGFLRLYYVENTGAAFGLFQGKNPLLAFLAFGVVVALVV
WFRELVRFWLGALALGLQLGGAVGNLIDRFRHGFVVDFIDFSFWPTFNLADSAITIGVLMLLYVLLRQGQLESPRAREAE
RIDAEQQIR
>Mature_169_residues
MRGWEIVACVAAIVLVVDQLSKALVLTFLAPGAPHAEVVIVPGFLRLYYVENTGAAFGLFQGKNPLLAFLAFGVVVALVV
WFRELVRFWLGALALGLQLGGAVGNLIDRFRHGFVVDFIDFSFWPTFNLADSAITIGVLMLLYVLLRQGQLESPRAREAE
RIDAEQQIR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=141, Percent_Identity=39.7163120567376, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18659; Mature: 18659

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGWEIVACVAAIVLVVDQLSKALVLTFLAPGAPHAEVVIVPGFLRLYYVENTGAAFGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCEEEEC
QGKNPLLAFLAFGVVVALVVWFRELVRFWLGALALGLQLGGAVGNLIDRFRHGFVVDFID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHH
FSFWPTFNLADSAITIGVLMLLYVLLRQGQLESPRAREAERIDAEQQIR
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHCCC
>Mature Secondary Structure
MRGWEIVACVAAIVLVVDQLSKALVLTFLAPGAPHAEVVIVPGFLRLYYVENTGAAFGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCEEEEC
QGKNPLLAFLAFGVVVALVVWFRELVRFWLGALALGLQLGGAVGNLIDRFRHGFVVDFID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHH
FSFWPTFNLADSAITIGVLMLLYVLLRQGQLESPRAREAERIDAEQQIR
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA