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The map label for this gene is radA [H]

Identifier: 221633019

GI number: 221633019

Start: 1000338

End: 1001750

Strand: Reverse

Name: radA [H]

Synonym: trd_1034

Alternate gene names: 221633019

Gene position: 1001750-1000338 (Counterclockwise)

Preceding gene: 221633020

Following gene: 221633018

Centisome position: 50.01

GC content: 62.63

Gene sequence:

>1413_bases
GTGCCACGGAGTCGAACACGCCGTCGCACCGTTTGGGTGTGCCAGTCCTGTGGGCTGGAAAGTTCGGGCTACTATGGGCG
CTGTCCGTCGTGCGGTGCATGGGGCACGATGGTCGAGCAAGCGGTGGACGCTACCCCGGCGACGGGAGACGCGAAAGGAA
CCGGCGCCCCGGTGCAGGAACTCTCGCGTGTAACCAGCGCCGAACGAACGCGCCTTTCGCTCCGATCACCGGAATTCGAT
CGTGTCCTCGGCGGCGGCCTGGTTCCTGGAGCACTGGTATTGCTCGGTGGCGACCCGGGTATCGGCAAGTCGACCCTGCT
CTTGCAAGCAGCGCTGCGTTTGGCAAGTGAGGGACTGCGGGTGCTGTATGTTGCTGCGGAAGAGTCGCCGGAGCAAATCA
GACTGCGGGCAGACCGACTCGGTAAGACCAGCGACGGGGTTCTGATTCTGGCGGAGACCGCGCTCGATCGCGCGATCGAG
ATCGCGCAAGAGCTCGATCCAGCCATTCTGATCGTCGATTCGATCCAGACAGTCTTCTTGAGCAGTAGCGAGTCGTCGCC
TGGGAGCGTTTCGCAAGTTCGCGACTGCACGGCACAACTCTTGCAGTTCGCCAAGCGAGCGAGGACCCCTGTCTTCCTCG
TCGGGCATGTGACGAAGGAAGGTCTGATCGCGGGTCCTCGAGTCGTCGAGCACATGGTCGATGTGGTTCTCTACCTCGAG
GGAGAGCGCTTCCATCAACACCGGCTGTTGCGTGCAGCCAAGAATCGGTTCGGATCGACCAACGAAATCGGTGTTTTCGA
AATGACGGATAGCGGACTCCTCGACGTGAGCAATCCCTCGGCGCTCTTCCTTGCGGAGCGGGCGTCGCATGCCGCAGGGA
GTGCAGTCGTGGTCACGCTGGAGGGGACGCGCCCCATTCTGATCGAGGTACAGGCGTTGACGAGTTCCGCGGGATACGGG
ACACCTCGGCGGATCGCCACTGGCTTCGATGCGACACGCTTACAAGTACTGGTCGCAGTGCTGTCGAAGCATGCCGGACT
CAAGCTCGGTGAGCAGGACGTCTTCGTCAATGTGACCGGGGGGTATCGGCTGGTCGAGCCGGCGGCCGATCTCGGTGTCG
CCCTCGCGATCGCTTCATCGGCGAGCGGTTTACCGCTCGATGACGATGCCGTCTTCATCGGTGAACTCGGGCTGGCGGGA
GAAGTACGCAGCGTGCATGGACTCGAGCGACGGCTCCAGGAGGCAGCTCGCCTGGGATTTCGCTCGGCGTATGTTCCAGC
ATCGGCGCGGATTTCGTCACCAGTGAGCGGGCTCCGCATCGTGGCCGTTGGTTCGATCGCGCAGGCGGTCAGTTCTTTAG
CTGTGCGCGCGGTGCAGGATCGACTCTCTCACGGTGTGCGACGCGAAGAATGA

Upstream 100 bases:

>100_bases
AGACGGTTTTCTCAGCGAGACACGGCACTGGTTCCGGCCAGTGCCGTGTTCGTTTATACTTCCCACTCGAACGGGTGTTC
TTGGTGCGAGAGGAGGATTC

Downstream 100 bases:

>100_bases
GCATCGCGAGCCGCTCCGCTGCATCGGGTATGACCAAGGAACGGCCGAGCTCACCCATCGCCCGGAGCTGCGCGGGGTCG
TCCAGAAGATGTCGGACCAA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MPRSRTRRRTVWVCQSCGLESSGYYGRCPSCGAWGTMVEQAVDATPATGDAKGTGAPVQELSRVTSAERTRLSLRSPEFD
RVLGGGLVPGALVLLGGDPGIGKSTLLLQAALRLASEGLRVLYVAAEESPEQIRLRADRLGKTSDGVLILAETALDRAIE
IAQELDPAILIVDSIQTVFLSSSESSPGSVSQVRDCTAQLLQFAKRARTPVFLVGHVTKEGLIAGPRVVEHMVDVVLYLE
GERFHQHRLLRAAKNRFGSTNEIGVFEMTDSGLLDVSNPSALFLAERASHAAGSAVVVTLEGTRPILIEVQALTSSAGYG
TPRRIATGFDATRLQVLVAVLSKHAGLKLGEQDVFVNVTGGYRLVEPAADLGVALAIASSASGLPLDDDAVFIGELGLAG
EVRSVHGLERRLQEAARLGFRSAYVPASARISSPVSGLRIVAVGSIAQAVSSLAVRAVQDRLSHGVRREE

Sequences:

>Translated_470_residues
MPRSRTRRRTVWVCQSCGLESSGYYGRCPSCGAWGTMVEQAVDATPATGDAKGTGAPVQELSRVTSAERTRLSLRSPEFD
RVLGGGLVPGALVLLGGDPGIGKSTLLLQAALRLASEGLRVLYVAAEESPEQIRLRADRLGKTSDGVLILAETALDRAIE
IAQELDPAILIVDSIQTVFLSSSESSPGSVSQVRDCTAQLLQFAKRARTPVFLVGHVTKEGLIAGPRVVEHMVDVVLYLE
GERFHQHRLLRAAKNRFGSTNEIGVFEMTDSGLLDVSNPSALFLAERASHAAGSAVVVTLEGTRPILIEVQALTSSAGYG
TPRRIATGFDATRLQVLVAVLSKHAGLKLGEQDVFVNVTGGYRLVEPAADLGVALAIASSASGLPLDDDAVFIGELGLAG
EVRSVHGLERRLQEAARLGFRSAYVPASARISSPVSGLRIVAVGSIAQAVSSLAVRAVQDRLSHGVRREE
>Mature_469_residues
PRSRTRRRTVWVCQSCGLESSGYYGRCPSCGAWGTMVEQAVDATPATGDAKGTGAPVQELSRVTSAERTRLSLRSPEFDR
VLGGGLVPGALVLLGGDPGIGKSTLLLQAALRLASEGLRVLYVAAEESPEQIRLRADRLGKTSDGVLILAETALDRAIEI
AQELDPAILIVDSIQTVFLSSSESSPGSVSQVRDCTAQLLQFAKRARTPVFLVGHVTKEGLIAGPRVVEHMVDVVLYLEG
ERFHQHRLLRAAKNRFGSTNEIGVFEMTDSGLLDVSNPSALFLAERASHAAGSAVVVTLEGTRPILIEVQALTSSAGYGT
PRRIATGFDATRLQVLVAVLSKHAGLKLGEQDVFVNVTGGYRLVEPAADLGVALAIASSASGLPLDDDAVFIGELGLAGE
VRSVHGLERRLQEAARLGFRSAYVPASARISSPVSGLRIVAVGSIAQAVSSLAVRAVQDRLSHGVRREE

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=451, Percent_Identity=45.2328159645233, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49726; Mature: 49595

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSRTRRRTVWVCQSCGLESSGYYGRCPSCGAWGTMVEQAVDATPATGDAKGTGAPVQE
CCCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LSRVTSAERTRLSLRSPEFDRVLGGGLVPGALVLLGGDPGIGKSTLLLQAALRLASEGLR
HHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
VLYVAAEESPEQIRLRADRLGKTSDGVLILAETALDRAIEIAQELDPAILIVDSIQTVFL
EEEEEECCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEECCEEEEE
SSSESSPGSVSQVRDCTAQLLQFAKRARTPVFLVGHVTKEGLIAGPRVVEHMVDVVLYLE
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEC
GERFHQHRLLRAAKNRFGSTNEIGVFEMTDSGLLDVSNPSALFLAERASHAAGSAVVVTL
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCEEEEEHHCCCCCCCEEEEEE
EGTRPILIEVQALTSSAGYGTPRRIATGFDATRLQVLVAVLSKHAGLKLGEQDVFVNVTG
CCCCEEEEEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEEECC
GYRLVEPAADLGVALAIASSASGLPLDDDAVFIGELGLAGEVRSVHGLERRLQEAARLGF
CEEEECCHHHHCEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
RSAYVPASARISSPVSGLRIVAVGSIAQAVSSLAVRAVQDRLSHGVRREE
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRSRTRRRTVWVCQSCGLESSGYYGRCPSCGAWGTMVEQAVDATPATGDAKGTGAPVQE
CCCCCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LSRVTSAERTRLSLRSPEFDRVLGGGLVPGALVLLGGDPGIGKSTLLLQAALRLASEGLR
HHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
VLYVAAEESPEQIRLRADRLGKTSDGVLILAETALDRAIEIAQELDPAILIVDSIQTVFL
EEEEEECCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEECCEEEEE
SSSESSPGSVSQVRDCTAQLLQFAKRARTPVFLVGHVTKEGLIAGPRVVEHMVDVVLYLE
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEC
GERFHQHRLLRAAKNRFGSTNEIGVFEMTDSGLLDVSNPSALFLAERASHAAGSAVVVTL
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCEEEEEHHCCCCCCCEEEEEE
EGTRPILIEVQALTSSAGYGTPRRIATGFDATRLQVLVAVLSKHAGLKLGEQDVFVNVTG
CCCCEEEEEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEEECC
GYRLVEPAADLGVALAIASSASGLPLDDDAVFIGELGLAGEVRSVHGLERRLQEAARLGF
CEEEECCHHHHCEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
RSAYVPASARISSPVSGLRIVAVGSIAQAVSSLAVRAVQDRLSHGVRREE
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]