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The map label for this gene is mtnA2 [H]

Identifier: 221632917

GI number: 221632917

Start: 900026

End: 901123

Strand: Reverse

Name: mtnA2 [H]

Synonym: trd_0919

Alternate gene names: 221632917

Gene position: 901123-900026 (Counterclockwise)

Preceding gene: 221632918

Following gene: 221632916

Centisome position: 44.99

GC content: 63.39

Gene sequence:

>1098_bases
ATGACGGATGCGCCGAGCGAATGGCGACCCCTTCACTGGACGGGAGAGTCGCTCGTCATCGTCGATCAAACGGCTCTTCC
GGATGAAGAGCGGCTTGTCGAGTGCCGTACGATCGATGACGTGGCGGCAGCAATCCGCGAGATGCGTGTCCGTGGGGCAC
CAGCCATCGGCATCAGCGCAGTCGCAGGGCTCGCTCTCGCGGTGCAGGGTGCAGCGCGAGAGGGGGGCGATTGGCGCCGA
GCGCTGTCCGCGGGGGAAGCGTTGTTGGCGAGCACGCGGCCGACCGCCGCCGATTTGTTTCATGGCCTGCAGGTGGCTCG
AGAGCGCGTGGCAAGCGCGGTGGATGCCGCGGAGGCAGCCCATCTTCTTGGCCAGCTGGTGCTGGAACTCTTGGATCGAC
AATGGGCCATCGATCGGGCACTCGCCGACTACGGTGCTGGGCTTTTGCGCTCTGGAACGCGCGTGCTCACACACTGTAAC
ACTGGAGCGTTGGGAACAGGAGCGTTTGGAACCGCACTCGGGATCATTCGCCGGGCGTATGAACTCGGTCGTTTGGAGCA
TGTCTGGGTCACGGAAACGCGCCCACGCTTGCAGGGAGCGCGCTTGACAGTGTGGGAACTCCGCCGCAGTGGAATACCGC
ATACGCTCATCGTGGACGGTGCGGCACCCTTCCTGCTCGCTCGGGGTGAGGTGGATGCCGTACTGGTCGGTGCGGATCGT
GTCGCGGCGAATGGGGATGTTGCCAACAAGATCGGTACACTCGGGCTCGCCGTGGCTGCGGAACGGTTCCGGGTTCCGTT
TTACGTAGCTGCTCCGCTTTCTACGTTCGATCCGGAGACGCCGGATGGAAATGCAATCCCGATCGAAGAGCGCGATCCAG
CTGAAGTGCTCCGCGTGAAAGGAACATGGATCGCACCGGCGGACACGCCGGTACGGAATCCTGCATTCGATGTGACACCA
CACTGGCTCGTGACAGCGCTCGTCACCGAGCGCGGTATCATTCCGGCGCCCGATAGGCGAAAGATCGCGAACTTTCTTGC
GGCGAACGGTCGAGGAACATCGGTCGAGCCAGGGGAAACGGGACGGGACGAACGGTGA

Upstream 100 bases:

>100_bases
TGCGGCGCGACGTGCCCATGAGCGTGATCGAGGACATCTGCCGAGCACTGCTGAGAACCGAATCGAGGATCGTGAGCGGG
AGAGGTGCCGGGGGAGACCG

Downstream 100 bases:

>100_bases
ACGGTCGAGTGATACCGTACGATATCGCTGATCTCACTTTAGCTGAGCAAGGAAGGAAGCGCATTGCTTGGGCAGCGCGG
GAGATGCCCGTTTTGCGCCT

Product: initiation factor 2b family protein

Products: NA

Alternate protein names: M1Pi 2; MTR-1-P isomerase 2; S-methyl-5-thioribose-1-phosphate isomerase 2 [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTDAPSEWRPLHWTGESLVIVDQTALPDEERLVECRTIDDVAAAIREMRVRGAPAIGISAVAGLALAVQGAAREGGDWRR
ALSAGEALLASTRPTAADLFHGLQVARERVASAVDAAEAAHLLGQLVLELLDRQWAIDRALADYGAGLLRSGTRVLTHCN
TGALGTGAFGTALGIIRRAYELGRLEHVWVTETRPRLQGARLTVWELRRSGIPHTLIVDGAAPFLLARGEVDAVLVGADR
VAANGDVANKIGTLGLAVAAERFRVPFYVAAPLSTFDPETPDGNAIPIEERDPAEVLRVKGTWIAPADTPVRNPAFDVTP
HWLVTALVTERGIIPAPDRRKIANFLAANGRGTSVEPGETGRDER

Sequences:

>Translated_365_residues
MTDAPSEWRPLHWTGESLVIVDQTALPDEERLVECRTIDDVAAAIREMRVRGAPAIGISAVAGLALAVQGAAREGGDWRR
ALSAGEALLASTRPTAADLFHGLQVARERVASAVDAAEAAHLLGQLVLELLDRQWAIDRALADYGAGLLRSGTRVLTHCN
TGALGTGAFGTALGIIRRAYELGRLEHVWVTETRPRLQGARLTVWELRRSGIPHTLIVDGAAPFLLARGEVDAVLVGADR
VAANGDVANKIGTLGLAVAAERFRVPFYVAAPLSTFDPETPDGNAIPIEERDPAEVLRVKGTWIAPADTPVRNPAFDVTP
HWLVTALVTERGIIPAPDRRKIANFLAANGRGTSVEPGETGRDER
>Mature_364_residues
TDAPSEWRPLHWTGESLVIVDQTALPDEERLVECRTIDDVAAAIREMRVRGAPAIGISAVAGLALAVQGAAREGGDWRRA
LSAGEALLASTRPTAADLFHGLQVARERVASAVDAAEAAHLLGQLVLELLDRQWAIDRALADYGAGLLRSGTRVLTHCNT
GALGTGAFGTALGIIRRAYELGRLEHVWVTETRPRLQGARLTVWELRRSGIPHTLIVDGAAPFLLARGEVDAVLVGADRV
AANGDVANKIGTLGLAVAAERFRVPFYVAAPLSTFDPETPDGNAIPIEERDPAEVLRVKGTWIAPADTPVRNPAFDVTPH
WLVTALVTERGIIPAPDRRKIANFLAANGRGTSVEPGETGRDER

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=351, Percent_Identity=42.1652421652422, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI23943880, Length=346, Percent_Identity=36.1271676300578, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4503503, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI78000158, Length=277, Percent_Identity=25.6317689530686, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI78000156, Length=277, Percent_Identity=25.6317689530686, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI187607323, Length=277, Percent_Identity=25.6317689530686, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557462, Length=339, Percent_Identity=38.0530973451327, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17557123, Length=187, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325375, Length=381, Percent_Identity=35.1706036745407, Blast_Score=200, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6322878, Length=146, Percent_Identity=34.9315068493151, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357667, Length=359, Percent_Identity=40.9470752089136, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24651647, Length=359, Percent_Identity=40.9470752089136, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21358605, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39005; Mature: 38874

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAPSEWRPLHWTGESLVIVDQTALPDEERLVECRTIDDVAAAIREMRVRGAPAIGISA
CCCCCCCCCCEEECCCEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHCCCCCCHHHH
VAGLALAVQGAAREGGDWRRALSAGEALLASTRPTAADLFHGLQVARERVASAVDAAEAA
HHHHHHHHHCCCCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HLLGQLVLELLDRQWAIDRALADYGAGLLRSGTRVLTHCNTGALGTGAFGTALGIIRRAY
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
ELGRLEHVWVTETRPRLQGARLTVWELRRSGIPHTLIVDGAAPFLLARGEVDAVLVGADR
HHCCEEEEEEECCCCCCCCCEEHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEECCC
VAANGDVANKIGTLGLAVAAERFRVPFYVAAPLSTFDPETPDGNAIPIEERDPAEVLRVK
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCCCCCHHHHEEEC
GTWIAPADTPVRNPAFDVTPHWLVTALVTERGIIPAPDRRKIANFLAANGRGTSVEPGET
CCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
GRDER
CCCCC
>Mature Secondary Structure 
TDAPSEWRPLHWTGESLVIVDQTALPDEERLVECRTIDDVAAAIREMRVRGAPAIGISA
CCCCCCCCCEEECCCEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHHCCCCCCHHHH
VAGLALAVQGAAREGGDWRRALSAGEALLASTRPTAADLFHGLQVARERVASAVDAAEAA
HHHHHHHHHCCCCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HLLGQLVLELLDRQWAIDRALADYGAGLLRSGTRVLTHCNTGALGTGAFGTALGIIRRAY
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
ELGRLEHVWVTETRPRLQGARLTVWELRRSGIPHTLIVDGAAPFLLARGEVDAVLVGADR
HHCCEEEEEEECCCCCCCCCEEHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEECCC
VAANGDVANKIGTLGLAVAAERFRVPFYVAAPLSTFDPETPDGNAIPIEERDPAEVLRVK
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCCCCCHHHHEEEC
GTWIAPADTPVRNPAFDVTPHWLVTALVTERGIIPAPDRRKIANFLAANGRGTSVEPGET
CCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
GRDER
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA