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The map label for this gene is soxA [H]

Identifier: 221632880

GI number: 221632880

Start: 861339

End: 862568

Strand: Reverse

Name: soxA [H]

Synonym: trd_0880

Alternate gene names: 221632880

Gene position: 862568-861339 (Counterclockwise)

Preceding gene: 221632881

Following gene: 221632879

Centisome position: 43.06

GC content: 61.38

Gene sequence:

>1230_bases
ATGCCTTTTCCGAGCCACGCTGATGCTGTCGTCATCGGTACGGGTGCCTTCGGCCTTTCCGTCACGTTGCAGCTGGCCCG
AATGGGGTTACGCAGCGTGGTCGCCTTGGATCGGTATCCGATCGCTTCCCAGACTTCGCCGCGCGCTGCTGGTCTCTTCA
AGCTCGTGCAAGCGGACGAACTGCGGACGCGCCTTGCTCGTCTGGCTGTAGAGACGGTGATGCACTTCGAACGTGACTTC
GGTGTGACGCTTCCCTATGTCCGGTCGGGAAGTCTCATGGTCGCGCGAACCGAACGCCATGCTCGCGTCATCGAGCAGGA
AGTGAGCGATGCGCAACGTTGGGGTGCCGATGTTCATCTCGTGTCAGCGCGCGAGGCGCAGGCGCTTGCACCGTTCCTGC
AGGCCGAGTCGATACTGCGTGCAGCCTATGTGCCCGGCGATATCTACATCGAGGAACCAGTGAGTCTCTTGAACGCCTTT
CGTGAGGCTGCCGAGCTTCTCGGTGCGCGCATCATCGGAAACGTGCCGGTCATCGGTATCGATGTGCGAGATTCGGCGGT
TCGAGCAGTGCTCACGCCCGAGGGGACGATCCAGACTGATATCGTCATCGATGCAGCGGGAGCATGGGTGCGTGCGGTTG
CTCGCCTAGCTGGCACTGACTTGGCTGTCCAGCCGATGCGGCACCAACTGGCTATCACACAGCCGATCAGCGGCACGCAG
AGCGAGCAGGCGATCGTGCGGATCTTCGATGCTGCGGTGTATGTCCGGCCGTGTCGGGGTGGTCTCATGTGGGGCGGGTT
CGAGGCGAATCCGCTACCGTTCGATCCCACCGCGCATGGCGACGATTTTCGTATCGAGATGACCCCACTCGATTTCGGAA
TTCTTCAGCAATGCGCGGAAAGTGTGCGCAACGTGGTTCCGGTTCTGCACGATGTGCCTGTTCAGGAGCATCGCGGTGGA
CTGTTTACGATGACACCGGATGGTCGCTTCGTCGTCGGACCAGTTCCCGCGGTCAGAGGATTTTGGGTTTTGAGTGGCTG
CAACGGGAGCGGTTTCTCCTTTTCGCCGGCGCTCGGGCGTTTGCTCGCAGAGTGGATCGTTCAGGGTCAGCCGTCGGTCG
ATCTGGCTGCGTTTGCGCCGGCACGACTGGCTGGCGTGGTCGACAAAGCCTCGCTGCGCGAGGCCGCGATCTTCCAGTAC
ACGCACTACTACGAGCCACTCGGAGAGTGA

Upstream 100 bases:

>100_bases
TTGGAGACGATGCGCTGGCAGCGCGGGGAACGGGTCCTCCTCAGCTGGCGAGCCGAGGATGCGGTCCTCCTACGGGGACG
ACATTGAGAGGAGGCGGTCG

Downstream 100 bases:

>100_bases
TGGTAACGCGGGGCCGGGGGAACTCCCGGACGGAGGGGCGCGATGGCGGCATCACTCACGGAAGCCAAGCGCACGGCATT
CCGCTGGATCGACGACAATG

Product: putative dehydrogenase protein

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPFPSHADAVVIGTGAFGLSVTLQLARMGLRSVVALDRYPIASQTSPRAAGLFKLVQADELRTRLARLAVETVMHFERDF
GVTLPYVRSGSLMVARTERHARVIEQEVSDAQRWGADVHLVSAREAQALAPFLQAESILRAAYVPGDIYIEEPVSLLNAF
REAAELLGARIIGNVPVIGIDVRDSAVRAVLTPEGTIQTDIVIDAAGAWVRAVARLAGTDLAVQPMRHQLAITQPISGTQ
SEQAIVRIFDAAVYVRPCRGGLMWGGFEANPLPFDPTAHGDDFRIEMTPLDFGILQQCAESVRNVVPVLHDVPVQEHRGG
LFTMTPDGRFVVGPVPAVRGFWVLSGCNGSGFSFSPALGRLLAEWIVQGQPSVDLAAFAPARLAGVVDKASLREAAIFQY
THYYEPLGE

Sequences:

>Translated_409_residues
MPFPSHADAVVIGTGAFGLSVTLQLARMGLRSVVALDRYPIASQTSPRAAGLFKLVQADELRTRLARLAVETVMHFERDF
GVTLPYVRSGSLMVARTERHARVIEQEVSDAQRWGADVHLVSAREAQALAPFLQAESILRAAYVPGDIYIEEPVSLLNAF
REAAELLGARIIGNVPVIGIDVRDSAVRAVLTPEGTIQTDIVIDAAGAWVRAVARLAGTDLAVQPMRHQLAITQPISGTQ
SEQAIVRIFDAAVYVRPCRGGLMWGGFEANPLPFDPTAHGDDFRIEMTPLDFGILQQCAESVRNVVPVLHDVPVQEHRGG
LFTMTPDGRFVVGPVPAVRGFWVLSGCNGSGFSFSPALGRLLAEWIVQGQPSVDLAAFAPARLAGVVDKASLREAAIFQY
THYYEPLGE
>Mature_408_residues
PFPSHADAVVIGTGAFGLSVTLQLARMGLRSVVALDRYPIASQTSPRAAGLFKLVQADELRTRLARLAVETVMHFERDFG
VTLPYVRSGSLMVARTERHARVIEQEVSDAQRWGADVHLVSAREAQALAPFLQAESILRAAYVPGDIYIEEPVSLLNAFR
EAAELLGARIIGNVPVIGIDVRDSAVRAVLTPEGTIQTDIVIDAAGAWVRAVARLAGTDLAVQPMRHQLAITQPISGTQS
EQAIVRIFDAAVYVRPCRGGLMWGGFEANPLPFDPTAHGDDFRIEMTPLDFGILQQCAESVRNVVPVLHDVPVQEHRGGL
FTMTPDGRFVVGPVPAVRGFWVLSGCNGSGFSFSPALGRLLAEWIVQGQPSVDLAAFAPARLAGVVDKASLREAAIFQYT
HYYEPLGE

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=383, Percent_Identity=31.331592689295, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI21361378, Length=383, Percent_Identity=31.331592689295, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI24797151, Length=392, Percent_Identity=26.2755102040816, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI194306651, Length=389, Percent_Identity=25.4498714652956, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71994045, Length=417, Percent_Identity=26.1390887290168, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994052, Length=424, Percent_Identity=25.9433962264151, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32563613, Length=381, Percent_Identity=24.6719160104987, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20130091, Length=408, Percent_Identity=27.4509803921569, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571104, Length=400, Percent_Identity=23.25, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 44236; Mature: 44105

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPSHADAVVIGTGAFGLSVTLQLARMGLRSVVALDRYPIASQTSPRAAGLFKLVQADE
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
LRTRLARLAVETVMHFERDFGVTLPYVRSGSLMVARTERHARVIEQEVSDAQRWGADVHL
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHCCCCEEE
VSAREAQALAPFLQAESILRAAYVPGDIYIEEPVSLLNAFREAAELLGARIIGNVPVIGI
EECHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DVRDSAVRAVLTPEGTIQTDIVIDAAGAWVRAVARLAGTDLAVQPMRHQLAITQPISGTQ
ECCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCEECCHHHHEEEECCCCCCC
SEQAIVRIFDAAVYVRPCRGGLMWGGFEANPLPFDPTAHGDDFRIEMTPLDFGILQQCAE
HHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
SVRNVVPVLHDVPVQEHRGGLFTMTPDGRFVVGPVPAVRGFWVLSGCNGSGFSFSPALGR
HHHHHHHHHHCCCCHHHCCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHH
LLAEWIVQGQPSVDLAAFAPARLAGVVDKASLREAAIFQYTHYYEPLGE
HHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFPSHADAVVIGTGAFGLSVTLQLARMGLRSVVALDRYPIASQTSPRAAGLFKLVQADE
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
LRTRLARLAVETVMHFERDFGVTLPYVRSGSLMVARTERHARVIEQEVSDAQRWGADVHL
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHCCCCEEE
VSAREAQALAPFLQAESILRAAYVPGDIYIEEPVSLLNAFREAAELLGARIIGNVPVIGI
EECHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DVRDSAVRAVLTPEGTIQTDIVIDAAGAWVRAVARLAGTDLAVQPMRHQLAITQPISGTQ
ECCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCEECCHHHHEEEECCCCCCC
SEQAIVRIFDAAVYVRPCRGGLMWGGFEANPLPFDPTAHGDDFRIEMTPLDFGILQQCAE
HHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
SVRNVVPVLHDVPVQEHRGGLFTMTPDGRFVVGPVPAVRGFWVLSGCNGSGFSFSPALGR
HHHHHHHHHHCCCCHHHCCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHH
LLAEWIVQGQPSVDLAAFAPARLAGVVDKASLREAAIFQYTHYYEPLGE
HHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9563845; 7887617; 8779579; 11035956 [H]