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The map label for this gene is ftsW [H]

Identifier: 221632842

GI number: 221632842

Start: 817245

End: 818549

Strand: Reverse

Name: ftsW [H]

Synonym: trd_0836

Alternate gene names: 221632842

Gene position: 818549-817245 (Counterclockwise)

Preceding gene: 221632843

Following gene: 221632841

Centisome position: 40.87

GC content: 59.16

Gene sequence:

>1305_bases
ATGAAGCGAGGAGGTCCGGTAGTCCGCTGGCTCGAGCTCCAACTCCTCGTGGTACCGGCGACCGCCGCTCTCGTGGGCCT
GCTGACGATCTACCTCGCGCGAGTCGGGACCACGCGGTGGACGTGGAGCGATCTGACCGTCAGTCTGGTCTTCATCACTG
TCCTCGGCTTAACAAGCATTTGGCTCGGGATCCTCGGCCTGCGCGGTGATCAGCTCGTCCTCCCGATCGTCGCGATGCTC
GCCTGTCTGGGATTACTGCTCAGCCAGCGTCTCAGTCCTACTGTTGGGGGTAGCGGGCTCTGGGCATCCCTGAGCCAGCG
GCAACTGGCGTATCTCCTGCTCGCTTTCGCTGTACTCTGGGTCACGGTGGCCGTGGTACGTCGGCTCGAGTGGATCAAGC
GCTTCAAGTACACCTGGGCACTGGGGGCATCAGCCTTGACATTGTTCACGATGCTTTTCGGAACTGACCTCGGTTCGGGT
GCCCGTCTTTGGCTCGATCTCGGACCGATCACCGTGCAACCTGGAGAAATCGTGAAAGTCTTGCTCGTATTTTTCCTGGC
GAGCTATCTCGACGACTACCGCGAGCTCCTGACGAGTTCGTACCGGATCGGACCACTTTCGCTGCCTCCCATCCCCTATC
TCATCCCGCTCGTCGTGATGTGGGGAATAGCGGTACTCGCCGTCGTTTTGCAGAACGACCTCGGTAATGCATTGCTCCTG
TACGGTGTCTTTCTCGTCATGCTGTACGCAGCATCAGGTCGCGGCTACTACGTTGGCGGAGGTCTTCTGGCTTTCGCCGG
AGCAGTCATCGTTGCACTGCGCGTTTTTCCCCGCGTCCAGCAGCGTATCCAAATCTGGTTGAATCCATGGAGCGACCCTA
CTGGATTGGGCATGCAACCTGTGCAGGCTGACTTAGCTTTCGCGCATGGCCATATCTTCGGATCCGGCTGGGGATTCGGG
TATCCACAGGCGATACCGGTTGTGGCAACCGACTACGCATTCGCTGCTATCGGGGAGGAACTGGGGAGTTTGGGAGCGAT
CGCCCTCGTCGCGCTCTATCTCGTGCTCATCCTTCGCGGTTTGTTCATCGCCCTACGCATCCGAAACGGCTTCGTTCGCT
TGTTGACAGTCGGACTCGTCACGGTTCTCGGCTTGCAGACGATCATTATTCTCGGTGGAAACGTGCGGCTGCTTCCGTTG
ACTGGGATCACCCTACCCTTCGTCAGTGCAGGTGGGAGCTCGCTGATCACGAATTTTCTCATCGTCGGACTGCTGCTCCG
TGCCAGCGAGCAGGCACGAGGATGA

Upstream 100 bases:

>100_bases
TGCGCTCCAGCATGCGATCGTGACCGACCCAGCTGCGATTTCCCCCGAAATACGGCAGCGATTCTCGCTTCTTCTCGGCA
AGTACCTGCCAGGGTGATCG

Downstream 100 bases:

>100_bases
ACGATGGTATGGAGAGTCGTCCCAGCAGCAGCATTTTTGGCCTCCCTCTGCGTCCTCGCCTACGGGATCGTACGGACGAA
CGATCGGACTGATCCGACCT

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKRGGPVVRWLELQLLVVPATAALVGLLTIYLARVGTTRWTWSDLTVSLVFITVLGLTSIWLGILGLRGDQLVLPIVAML
ACLGLLLSQRLSPTVGGSGLWASLSQRQLAYLLLAFAVLWVTVAVVRRLEWIKRFKYTWALGASALTLFTMLFGTDLGSG
ARLWLDLGPITVQPGEIVKVLLVFFLASYLDDYRELLTSSYRIGPLSLPPIPYLIPLVVMWGIAVLAVVLQNDLGNALLL
YGVFLVMLYAASGRGYYVGGGLLAFAGAVIVALRVFPRVQQRIQIWLNPWSDPTGLGMQPVQADLAFAHGHIFGSGWGFG
YPQAIPVVATDYAFAAIGEELGSLGAIALVALYLVLILRGLFIALRIRNGFVRLLTVGLVTVLGLQTIIILGGNVRLLPL
TGITLPFVSAGGSSLITNFLIVGLLLRASEQARG

Sequences:

>Translated_434_residues
MKRGGPVVRWLELQLLVVPATAALVGLLTIYLARVGTTRWTWSDLTVSLVFITVLGLTSIWLGILGLRGDQLVLPIVAML
ACLGLLLSQRLSPTVGGSGLWASLSQRQLAYLLLAFAVLWVTVAVVRRLEWIKRFKYTWALGASALTLFTMLFGTDLGSG
ARLWLDLGPITVQPGEIVKVLLVFFLASYLDDYRELLTSSYRIGPLSLPPIPYLIPLVVMWGIAVLAVVLQNDLGNALLL
YGVFLVMLYAASGRGYYVGGGLLAFAGAVIVALRVFPRVQQRIQIWLNPWSDPTGLGMQPVQADLAFAHGHIFGSGWGFG
YPQAIPVVATDYAFAAIGEELGSLGAIALVALYLVLILRGLFIALRIRNGFVRLLTVGLVTVLGLQTIIILGGNVRLLPL
TGITLPFVSAGGSSLITNFLIVGLLLRASEQARG
>Mature_434_residues
MKRGGPVVRWLELQLLVVPATAALVGLLTIYLARVGTTRWTWSDLTVSLVFITVLGLTSIWLGILGLRGDQLVLPIVAML
ACLGLLLSQRLSPTVGGSGLWASLSQRQLAYLLLAFAVLWVTVAVVRRLEWIKRFKYTWALGASALTLFTMLFGTDLGSG
ARLWLDLGPITVQPGEIVKVLLVFFLASYLDDYRELLTSSYRIGPLSLPPIPYLIPLVVMWGIAVLAVVLQNDLGNALLL
YGVFLVMLYAASGRGYYVGGGLLAFAGAVIVALRVFPRVQQRIQIWLNPWSDPTGLGMQPVQADLAFAHGHIFGSGWGFG
YPQAIPVVATDYAFAAIGEELGSLGAIALVALYLVLILRGLFIALRIRNGFVRLLTVGLVTVLGLQTIIILGGNVRLLPL
TGITLPFVSAGGSSLITNFLIVGLLLRASEQARG

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=339, Percent_Identity=29.2035398230088, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786853, Length=265, Percent_Identity=33.5849056603774, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46761; Mature: 46761

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGGPVVRWLELQLLVVPATAALVGLLTIYLARVGTTRWTWSDLTVSLVFITVLGLTSI
CCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
WLGILGLRGDQLVLPIVAMLACLGLLLSQRLSPTVGGSGLWASLSQRQLAYLLLAFAVLW
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VTVAVVRRLEWIKRFKYTWALGASALTLFTMLFGTDLGSGARLWLDLGPITVQPGEIVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEECCHHHHHH
LLVFFLASYLDDYRELLTSSYRIGPLSLPPIPYLIPLVVMWGIAVLAVVLQNDLGNALLL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YGVFLVMLYAASGRGYYVGGGLLAFAGAVIVALRVFPRVQQRIQIWLNPWSDPTGLGMQP
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
VQADLAFAHGHIFGSGWGFGYPQAIPVVATDYAFAAIGEELGSLGAIALVALYLVLILRG
HHHHHHHHHCCEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIALRIRNGFVRLLTVGLVTVLGLQTIIILGGNVRLLPLTGITLPFVSAGGSSLITNFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHCCCCHHHHHHHH
IVGLLLRASEQARG
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKRGGPVVRWLELQLLVVPATAALVGLLTIYLARVGTTRWTWSDLTVSLVFITVLGLTSI
CCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
WLGILGLRGDQLVLPIVAMLACLGLLLSQRLSPTVGGSGLWASLSQRQLAYLLLAFAVLW
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VTVAVVRRLEWIKRFKYTWALGASALTLFTMLFGTDLGSGARLWLDLGPITVQPGEIVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEECCHHHHHH
LLVFFLASYLDDYRELLTSSYRIGPLSLPPIPYLIPLVVMWGIAVLAVVLQNDLGNALLL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YGVFLVMLYAASGRGYYVGGGLLAFAGAVIVALRVFPRVQQRIQIWLNPWSDPTGLGMQP
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
VQADLAFAHGHIFGSGWGFGYPQAIPVVATDYAFAAIGEELGSLGAIALVALYLVLILRG
HHHHHHHHHCCEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIALRIRNGFVRLLTVGLVTVLGLQTIIILGGNVRLLPLTGITLPFVSAGGSSLITNFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHCCCCHHHHHHHH
IVGLLLRASEQARG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]