Click here to switch to the map view.

The map label for this gene is mtaP [H]

Identifier: 221632843

GI number: 221632843

Start: 818553

End: 819422

Strand: Reverse

Name: mtaP [H]

Synonym: trd_0837

Alternate gene names: 221632843

Gene position: 819422-818553 (Counterclockwise)

Preceding gene: 221632851

Following gene: 221632842

Centisome position: 40.91

GC content: 61.03

Gene sequence:

>870_bases
ATGGACGCTGAACTCGGTGTGATCGGTGGAAGCGGTCTCTATCGCATGCCGGAGCTCACCGATGTGGAGGAGATCGCCAT
CGAGACCCCCTTCGGTCGACCGAGCGATACCATCACGCTGGGAACACTCCATGGGATGCGCGTCGCTTTCATACCGCGAC
ACGGTCGTGCGCACCAGCACAGTCCGAGCAATGTACCAGCCAGGGCCAATTTTTGGGCACTCAAGTCGCTCGGAGTGCAG
TGGGTCGTCTCCGTGAGTGCTGTCGGCAGTCTCCGCGAGGAGATCGCACCACTCGATTTCGTCGTACCCGATCAAGTCGT
CGACCGAACTGTCCGGCGGCCTCGCTCGTTTTTCGATGAGAGCGGCCTGGTTGTCCATGTCACGCTGGATGAGCCGTTTT
GCCCGGAACTGCGGTGGGCACTCACCCAAGCAGCGATCGCGGCCGGCGTGCGCGTCCACGACCGAGGGACTTATATCTGC
ATCGAAGGCCCACAGTTCTCGACGCGCGCAGAATCGAACCTGTACCGTTCGTGGGGACTGGACATCATCGGTATGACGGC
GATGCCGGAGGTTCGTCTGGCTCGGGAGGCAGAACTCTGTTTCGCGCTGCTCGCACTGGTGACAGACTACGATGTGTGGC
ATGCCGAAGAAGAACCGGTGAGCGTATCGGTCGTGTTGGAGCGCTTGCATCAGAACGTCCAAGCAGCGCAACGTGCCCTC
AGCGCACTGATCGAGTACCTGCGAGCACTACCAGGGCGATGCGGCTGTCGCACTGCGCTCCAGCATGCGATCGTGACCGA
CCCAGCTGCGATTTCCCCCGAAATACGGCAGCGATTCTCGCTTCTTCTCGGCAAGTACCTGCCAGGGTGA

Upstream 100 bases:

>100_bases
GACGCAACTCGATGTTATCCTGCACATGCATCGAGCGCACGGCCTCCCAGCGAAGTGTAACGTGCGCCGTAGGACCGACT
GAACGAGGGAAGGACAACTG

Downstream 100 bases:

>100_bases
TCGATGAAGCGAGGAGGTCCGGTAGTCCGCTGGCTCGAGCTCCAACTCCTCGTGGTACCGGCGACCGCCGCTCTCGTGGG
CCTGCTGACGATCTACCTCG

Product: methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDAELGVIGGSGLYRMPELTDVEEIAIETPFGRPSDTITLGTLHGMRVAFIPRHGRAHQHSPSNVPARANFWALKSLGVQ
WVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPRSFFDESGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYIC
IEGPQFSTRAESNLYRSWGLDIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNVQAAQRAL
SALIEYLRALPGRCGCRTALQHAIVTDPAAISPEIRQRFSLLLGKYLPG

Sequences:

>Translated_289_residues
MDAELGVIGGSGLYRMPELTDVEEIAIETPFGRPSDTITLGTLHGMRVAFIPRHGRAHQHSPSNVPARANFWALKSLGVQ
WVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPRSFFDESGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYIC
IEGPQFSTRAESNLYRSWGLDIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNVQAAQRAL
SALIEYLRALPGRCGCRTALQHAIVTDPAAISPEIRQRFSLLLGKYLPG
>Mature_289_residues
MDAELGVIGGSGLYRMPELTDVEEIAIETPFGRPSDTITLGTLHGMRVAFIPRHGRAHQHSPSNVPARANFWALKSLGVQ
WVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPRSFFDESGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYIC
IEGPQFSTRAESNLYRSWGLDIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNVQAAQRAL
SALIEYLRALPGRCGCRTALQHAIVTDPAAISPEIRQRFSLLLGKYLPG

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=245, Percent_Identity=46.530612244898, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71980569, Length=238, Percent_Identity=41.5966386554622, Blast_Score=190, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6323045, Length=303, Percent_Identity=39.2739273927393, Blast_Score=201, Evalue=9e-53,
Organism=Drosophila melanogaster, GI20130079, Length=241, Percent_Identity=41.9087136929461, Blast_Score=197, Evalue=6e-51,
Organism=Drosophila melanogaster, GI221459247, Length=250, Percent_Identity=36, Blast_Score=171, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31898; Mature: 31898

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAELGVIGGSGLYRMPELTDVEEIAIETPFGRPSDTITLGTLHGMRVAFIPRHGRAHQH
CCCCEEEECCCCCCCCCCCCCHHHHHEECCCCCCCCEEEEEEECCEEEEEEECCCCCCCC
SPSNVPARANFWALKSLGVQWVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPRSFFDE
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
SGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYICIEGPQFSTRAESNLYRSWGL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHCCC
DIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNVQAAQRAL
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SALIEYLRALPGRCGCRTALQHAIVTDPAAISPEIRQRFSLLLGKYLPG
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDAELGVIGGSGLYRMPELTDVEEIAIETPFGRPSDTITLGTLHGMRVAFIPRHGRAHQH
CCCCEEEECCCCCCCCCCCCCHHHHHEECCCCCCCCEEEEEEECCEEEEEEECCCCCCCC
SPSNVPARANFWALKSLGVQWVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPRSFFDE
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
SGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYICIEGPQFSTRAESNLYRSWGL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHCCC
DIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNVQAAQRAL
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SALIEYLRALPGRCGCRTALQHAIVTDPAAISPEIRQRFSLLLGKYLPG
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA