Click here to switch to the map view.

The map label for this gene is btuR [C]

Identifier: 221632811

GI number: 221632811

Start: 786631

End: 787176

Strand: Reverse

Name: btuR [C]

Synonym: trd_0805

Alternate gene names: 221632811

Gene position: 787176-786631 (Counterclockwise)

Preceding gene: 221632812

Following gene: 221632810

Centisome position: 39.3

GC content: 61.36

Gene sequence:

>546_bases
ATGGACGTCGATCGGGGCCAAACGGAACGCGCGTATCTCATGCTACTGGTCGGTGACGAGCGTCGGACGTCCGATGCAGC
GCTCGGTATTGCGTTGCGTGGTGCTGGGCATGGGTTGCGAATTCATATCATTGAGTTCCTGAAGACAGGGCGCGAGCGGG
GAGAAGTTGCCGCCGTTTCTTTCTTGACCGGCGTCACTCTCTCCCAGTACGGCATGATCGATGTCCGGACGCGCCCGGAA
GAGATCCGCGGCCCAGCCATTTCGCCGGAGCGCTTGCAGGCTGCGCTACGAGAGGCGAGGCAACATGTGGCACTGCGGGT
GACGAATATCCTGATCCTCGACGGCCTTTTGACCTTGGTCGATGAGGGAATGGTCGACGAGAAGACCATTCTCGAGTTGG
TCGAGCGGGCCGCGCCCTGGACCGATATTGTCCTGACGGGGCGAGCGGCGACACCGGCACTGCAAGAGGCGGCCGACAGC
GTCACGCTCATGCAAACGATCAAATCGCGGGAACAGGAGCCGCTCCGACGAGGACTGCACTATTGA

Upstream 100 bases:

>100_bases
CGCGCGCGACCCGATGGATCACTGGTACGTATTCCAGGAAGGCAACGGAATGAAAGACGCCAACACGGTATCATGACCGT
GAAAAGGGATGGAGGGCATG

Downstream 100 bases:

>100_bases
GCGGGAGGTACCTGTGCGACGACCGATCCGTGTCCTGATCGCAAAACCTGGCCTCGATGGCCATGACCGTGGTGCGAAGG
TCCTTGCACGAGCACTGCGT

Product: putative ATP:corrinoid adenosyltransferase BtuR/CobO/CobP

Products: triphosphate; adenosylcob(III)yrinic acid a,c-diamide; Adenosyl cobinamide

Alternate protein names: Cob(I)Yrinic Acid A C-Diamide Adenosyltransferase; ATPCorrinoid Adenosyltransferase; ATPCorrinoid Adenosyltransferase BtuR/CobO/CobP; Cobalamin Adenosyltransferase CobA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MDVDRGQTERAYLMLLVGDERRTSDAALGIALRGAGHGLRIHIIEFLKTGRERGEVAAVSFLTGVTLSQYGMIDVRTRPE
EIRGPAISPERLQAALREARQHVALRVTNILILDGLLTLVDEGMVDEKTILELVERAAPWTDIVLTGRAATPALQEAADS
VTLMQTIKSREQEPLRRGLHY

Sequences:

>Translated_181_residues
MDVDRGQTERAYLMLLVGDERRTSDAALGIALRGAGHGLRIHIIEFLKTGRERGEVAAVSFLTGVTLSQYGMIDVRTRPE
EIRGPAISPERLQAALREARQHVALRVTNILILDGLLTLVDEGMVDEKTILELVERAAPWTDIVLTGRAATPALQEAADS
VTLMQTIKSREQEPLRRGLHY
>Mature_181_residues
MDVDRGQTERAYLMLLVGDERRTSDAALGIALRGAGHGLRIHIIEFLKTGRERGEVAAVSFLTGVTLSQYGMIDVRTRPE
EIRGPAISPERLQAALREARQHVALRVTNILILDGLLTLVDEGMVDEKTILELVERAAPWTDIVLTGRAATPALQEAADS
VTLMQTIKSREQEPLRRGLHY

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.17

Molecular weight: Translated: 20018; Mature: 20018

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVDRGQTERAYLMLLVGDERRTSDAALGIALRGAGHGLRIHIIEFLKTGRERGEVAAVS
CCCCCCCCCCEEEEEEECCCCCCCHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
FLTGVTLSQYGMIDVRTRPEEIRGPAISPERLQAALREARQHVALRVTNILILDGLLTLV
HHHHHHHHHCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEGMVDEKTILELVERAAPWTDIVLTGRAATPALQEAADSVTLMQTIKSREQEPLRRGLH
HCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C
>Mature Secondary Structure
MDVDRGQTERAYLMLLVGDERRTSDAALGIALRGAGHGLRIHIIEFLKTGRERGEVAAVS
CCCCCCCCCCEEEEEEECCCCCCCHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
FLTGVTLSQYGMIDVRTRPEEIRGPAISPERLQAALREARQHVALRVTNILILDGLLTLV
HHHHHHHHHCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEGMVDEKTILELVERAAPWTDIVLTGRAATPALQEAADSVTLMQTIKSREQEPLRRGLH
HCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)yrinic acid a,c-diamide; cobinamide

Specific reaction: (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA