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The map label for this gene is sbm [H]

Identifier: 221632810

GI number: 221632810

Start: 786207

End: 786617

Strand: Reverse

Name: sbm [H]

Synonym: trd_0804

Alternate gene names: 221632810

Gene position: 786617-786207 (Counterclockwise)

Preceding gene: 221632811

Following gene: 221632809

Centisome position: 39.27

GC content: 59.12

Gene sequence:

>411_bases
GTGCGACGACCGATCCGTGTCCTGATCGCAAAACCTGGCCTCGATGGCCATGACCGTGGTGCGAAGGTCCTTGCACGAGC
ACTGCGTGATGCGGGAATGGAAGTGATCTACACCGGTCTCTTCCAAACGCCTGAAACGATCGCGCGCAGCGCCGTCGATG
AGGATGTCGATGTTGTCGGCCTGAGTATTCTCTCGGGCGCACACAACCAACTCGTACCGGAAGTAGTGCGAGCGCTGCGG
TCCGCCGGGAAAGAGGATGCTCTGGTGCTCGTCGGCGGAATCATTCCGGAAGAAGACATCCCCTTCCTCAAGGCACAGGG
AGTTGCCGAAGTTTTCGGCCCCGGTACGCCGCTATCAGAAATCATTCGCTTCATCGAAACGCATGTTGGTGAGCCAGTGA
GGGGCGCGTGA

Upstream 100 bases:

>100_bases
CTGCAAGAGGCGGCCGACAGCGTCACGCTCATGCAAACGATCAAATCGCGGGAACAGGAGCCGCTCCGACGAGGACTGCA
CTATTGAGCGGGAGGTACCT

Downstream 100 bases:

>100_bases
GTCGAGATGTCGCAGGACTTGGGAAACTTGCTCGAAGGTGTTCGGAATCGGGATCGTTCCTCCCTTGCGCGCGCACTCTC
CCTCTTGGAGCGTTATCCTG

Product: Sbm protein

Products: succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MRRPIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGLFQTPETIARSAVDEDVDVVGLSILSGAHNQLVPEVVRALR
SAGKEDALVLVGGIIPEEDIPFLKAQGVAEVFGPGTPLSEIIRFIETHVGEPVRGA

Sequences:

>Translated_136_residues
MRRPIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGLFQTPETIARSAVDEDVDVVGLSILSGAHNQLVPEVVRALR
SAGKEDALVLVGGIIPEEDIPFLKAQGVAEVFGPGTPLSEIIRFIETHVGEPVRGA
>Mature_136_residues
MRRPIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGLFQTPETIARSAVDEDVDVVGLSILSGAHNQLVPEVVRALR
SAGKEDALVLVGGIIPEEDIPFLKAQGVAEVFGPGTPLSEIIRFIETHVGEPVRGA

Specific function: Unknown

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=115, Percent_Identity=53.9130434782609, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1789284, Length=122, Percent_Identity=54.0983606557377, Blast_Score=133, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144500, Length=134, Percent_Identity=45.5223880597015, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: NA

Molecular weight: Translated: 14482; Mature: 14482

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGLFQTPETIARSAVDEDVDVVG
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCHHHHH
LSILSGAHNQLVPEVVRALRSAGKEDALVLVGGIIPEEDIPFLKAQGVAEVFGPGTPLSE
HHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCHHHHCCCCCCHHH
IIRFIETHVGEPVRGA
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRRPIRVLIAKPGLDGHDRGAKVLARALRDAGMEVIYTGLFQTPETIARSAVDEDVDVVG
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCHHHHH
LSILSGAHNQLVPEVVRALRSAGKEDALVLVGGIIPEEDIPFLKAQGVAEVFGPGTPLSE
HHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCHHHHCCCCCCHHH
IIRFIETHVGEPVRGA
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Co [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-methylmalonyl-CoA [C]

Specific reaction: L-methylmalonyl-CoA = succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1355087; 9278503 [H]