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The map label for this gene is cysS [H]

Identifier: 221632709

GI number: 221632709

Start: 685696

End: 687093

Strand: Reverse

Name: cysS [H]

Synonym: trd_0697

Alternate gene names: 221632709

Gene position: 687093-685696 (Counterclockwise)

Preceding gene: 221632710

Following gene: 221632708

Centisome position: 34.3

GC content: 59.8

Gene sequence:

>1398_bases
ATGACGTTGCGCGTGACGAACACGCTGACCCGAGAGAAGGAACAGTTCGAAACATTGGAGCCTGGGCACGTGCGCATGTA
TGTGTGCGGGCCGACCGTCTATAGCGATGCCCATATCGGTCATGCCATGTCAGCGATCGTCTTCGATATGATTCGCCGGT
ATCTCGAGTACAGCGGCTATCGTGTCACCTTCGCGATGAACTTCACCGACATCGACGACAAGATCATTCAGCGCGCCGCC
ACGCTCGGCCTGCCCCCTCATGAACTGGCTGAGCAACTCATCGATGCCTGGCTCGATGAGACAGCCGCGCTCAACATCAA
ACCGGCGACGATCTACCCCCGTGCCACTCAGGAGATACCGACCATCATCGAGATGGTCAAGGGTCTTCTCGTCAAAGGAC
ATGCCTACACGATCGACGGAGATGTCTACTTCCGCGTTCTTTCGTTCCCGGAATACGGGAAACTCTCACACCGCACGCTG
GAGGAGATGCTAGCCGGCGCCCGTGTCGAAATCGATCCCCGCAAGGAGCATCCCATGGACTTTGCTCTCTGGAAGGCTGC
CAAACCGGGCGAGCCAGCGTGGGACAGTCCATGGGGCCCCGGACGCCCCGGATGGCATATCGAATGCAGCGCTATGATCT
ATCGGCATCTCGGTGAACAGATCGACATTCATGGCGGGGGAGCGGATCTCATTTTTCCCCACCACGAGAACGAAATCGCT
CAATCCGAGGCTTTTACCGGAAAGAAGCCGTTCGTCCGTTACTGGCTGCACAATGGACTCCTCCAGCTCGGTGGCGAAAA
GATGAGCAAATCGATCGGCAACTTGATCACCATTCGCGAACTCCTGGCGCGGAACGGTGCTGGCCCCTTCCGCTTGCTGG
TGCTCAGCTCGCACTATCGTAGTCCCCTCACCTTCACCGAGGAAGCGTTCGAGGCAGCAACCCGAGGCTTCGATCGACTG
CGGCTCGCTGTGCAGGGCGTCGAACCGGCTGAGTTACCGAACCGCCCGGAGCACGAACTCGCCACGCTCGCCGATGCGAC
GCGACTCGCCTTCCGTCAAGCCATGGACGACGACTTCGACACCCCTGTCGCGCTCGCCCGCCTTTTCGAGTTAGCCCGTG
CCATCAATCGAGCACGAGCCTCTGGCGAGCGATTGGAGGCGATCCGCTACGCTCAGTTCACCTTACTCGAACTCGCGACT
GTGCTCGGCTTCCGGTTCGACGAGCAATCGACCGGTCGCCAGTCAGCGGAACCCTTCATCGACCTTCTTCTCGACGTGCG
AGCACGCTTACGGGCCCAGCGTCAATGGGAACTGGCGGACTACATTCGCGGTCGGCTCAACGAACTCGGCGTCCTCGTCG
AGGATACACCGGGCGGAACGACCTGGCGTTGGACATGA

Upstream 100 bases:

>100_bases
GGCGACCGATCCTGGTCGCCCGCTTCTTTTCTGATCTGATCCGTGCAGGCTTCAGGTATGCTCTGGTGGGACGCGACGGT
GACGCGAGGAGAACGAACCG

Downstream 100 bases:

>100_bases
GGCGGTTACAGCCCGGTCGGCCGAGCGAGTATCTCTACGGTCGTAACGCGGTCGCGGAAGCCCTCAGGGGACGGCGACGT
CACCGACGACTCTTTGTCGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTLRVTNTLTREKEQFETLEPGHVRMYVCGPTVYSDAHIGHAMSAIVFDMIRRYLEYSGYRVTFAMNFTDIDDKIIQRAA
TLGLPPHELAEQLIDAWLDETAALNIKPATIYPRATQEIPTIIEMVKGLLVKGHAYTIDGDVYFRVLSFPEYGKLSHRTL
EEMLAGARVEIDPRKEHPMDFALWKAAKPGEPAWDSPWGPGRPGWHIECSAMIYRHLGEQIDIHGGGADLIFPHHENEIA
QSEAFTGKKPFVRYWLHNGLLQLGGEKMSKSIGNLITIRELLARNGAGPFRLLVLSSHYRSPLTFTEEAFEAATRGFDRL
RLAVQGVEPAELPNRPEHELATLADATRLAFRQAMDDDFDTPVALARLFELARAINRARASGERLEAIRYAQFTLLELAT
VLGFRFDEQSTGRQSAEPFIDLLLDVRARLRAQRQWELADYIRGRLNELGVLVEDTPGGTTWRWT

Sequences:

>Translated_465_residues
MTLRVTNTLTREKEQFETLEPGHVRMYVCGPTVYSDAHIGHAMSAIVFDMIRRYLEYSGYRVTFAMNFTDIDDKIIQRAA
TLGLPPHELAEQLIDAWLDETAALNIKPATIYPRATQEIPTIIEMVKGLLVKGHAYTIDGDVYFRVLSFPEYGKLSHRTL
EEMLAGARVEIDPRKEHPMDFALWKAAKPGEPAWDSPWGPGRPGWHIECSAMIYRHLGEQIDIHGGGADLIFPHHENEIA
QSEAFTGKKPFVRYWLHNGLLQLGGEKMSKSIGNLITIRELLARNGAGPFRLLVLSSHYRSPLTFTEEAFEAATRGFDRL
RLAVQGVEPAELPNRPEHELATLADATRLAFRQAMDDDFDTPVALARLFELARAINRARASGERLEAIRYAQFTLLELAT
VLGFRFDEQSTGRQSAEPFIDLLLDVRARLRAQRQWELADYIRGRLNELGVLVEDTPGGTTWRWT
>Mature_464_residues
TLRVTNTLTREKEQFETLEPGHVRMYVCGPTVYSDAHIGHAMSAIVFDMIRRYLEYSGYRVTFAMNFTDIDDKIIQRAAT
LGLPPHELAEQLIDAWLDETAALNIKPATIYPRATQEIPTIIEMVKGLLVKGHAYTIDGDVYFRVLSFPEYGKLSHRTLE
EMLAGARVEIDPRKEHPMDFALWKAAKPGEPAWDSPWGPGRPGWHIECSAMIYRHLGEQIDIHGGGADLIFPHHENEIAQ
SEAFTGKKPFVRYWLHNGLLQLGGEKMSKSIGNLITIRELLARNGAGPFRLLVLSSHYRSPLTFTEEAFEAATRGFDRLR
LAVQGVEPAELPNRPEHELATLADATRLAFRQAMDDDFDTPVALARLFELARAINRARASGERLEAIRYAQFTLLELATV
LGFRFDEQSTGRQSAEPFIDLLLDVRARLRAQRQWELADYIRGRLNELGVLVEDTPGGTTWRWT

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=465, Percent_Identity=39.3548387096774, Blast_Score=278, Evalue=9e-75,
Organism=Homo sapiens, GI21269877, Length=406, Percent_Identity=35.4679802955665, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI10835051, Length=406, Percent_Identity=34.7290640394089, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI303304987, Length=406, Percent_Identity=35.4679802955665, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI62240992, Length=406, Percent_Identity=35.4679802955665, Blast_Score=205, Evalue=9e-53,
Organism=Escherichia coli, GI1786737, Length=472, Percent_Identity=45.1271186440678, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17509795, Length=440, Percent_Identity=32.2727272727273, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17509797, Length=440, Percent_Identity=32.2727272727273, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=301, Percent_Identity=37.8737541528239, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19922218, Length=502, Percent_Identity=34.2629482071713, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI19922364, Length=321, Percent_Identity=35.5140186915888, Blast_Score=189, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52666; Mature: 52535

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVTNTLTREKEQFETLEPGHVRMYVCGPTVYSDAHIGHAMSAIVFDMIRRYLEYSGY
CEEEECHHHHHHHHHHHCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHCCCE
RVTFAMNFTDIDDKIIQRAATLGLPPHELAEQLIDAWLDETAALNIKPATIYPRATQEIP
EEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCHHHHH
TIIEMVKGLLVKGHAYTIDGDVYFRVLSFPEYGKLSHRTLEEMLAGARVEIDPRKEHPMD
HHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
FALWKAAKPGEPAWDSPWGPGRPGWHIECSAMIYRHLGEQIDIHGGGADLIFPHHENEIA
HHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCCCCCHHH
QSEAFTGKKPFVRYWLHNGLLQLGGEKMSKSIGNLITIRELLARNGAGPFRLLVLSSHYR
HHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SPLTFTEEAFEAATRGFDRLRLAVQGVEPAELPNRPEHELATLADATRLAFRQAMDDDFD
CCCCHHHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TPVALARLFELARAINRARASGERLEAIRYAQFTLLELATVLGFRFDEQSTGRQSAEPFI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
DLLLDVRARLRAQRQWELADYIRGRLNELGVLVEDTPGGTTWRWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TLRVTNTLTREKEQFETLEPGHVRMYVCGPTVYSDAHIGHAMSAIVFDMIRRYLEYSGY
EEEECHHHHHHHHHHHCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHCCCE
RVTFAMNFTDIDDKIIQRAATLGLPPHELAEQLIDAWLDETAALNIKPATIYPRATQEIP
EEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCHHHHH
TIIEMVKGLLVKGHAYTIDGDVYFRVLSFPEYGKLSHRTLEEMLAGARVEIDPRKEHPMD
HHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
FALWKAAKPGEPAWDSPWGPGRPGWHIECSAMIYRHLGEQIDIHGGGADLIFPHHENEIA
HHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCCCCCHHH
QSEAFTGKKPFVRYWLHNGLLQLGGEKMSKSIGNLITIRELLARNGAGPFRLLVLSSHYR
HHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SPLTFTEEAFEAATRGFDRLRLAVQGVEPAELPNRPEHELATLADATRLAFRQAMDDDFD
CCCCHHHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TPVALARLFELARAINRARASGERLEAIRYAQFTLLELATVLGFRFDEQSTGRQSAEPFI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
DLLLDVRARLRAQRQWELADYIRGRLNELGVLVEDTPGGTTWRWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA