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The map label for this gene is yacO [H]

Identifier: 221632708

GI number: 221632708

Start: 684914

End: 685699

Strand: Reverse

Name: yacO [H]

Synonym: trd_0696

Alternate gene names: 221632708

Gene position: 685699-684914 (Counterclockwise)

Preceding gene: 221632709

Following gene: 221632706

Centisome position: 34.23

GC content: 63.23

Gene sequence:

>786_bases
ATGAGGCGGTTACAGCCCGGTCGGCCGAGCGAGTATCTCTACGGTCGTAACGCGGTCGCGGAAGCCCTCAGGGGACGGCG
ACGTCACCGACGACTCTTTGTCGCGAGCGGGATCGAGACGCATGGCCGTATCGTGGCGCTGATGGAAGCAGCGCGCGTCC
GCGGTATTCCGGTCATCGTCATCCCGCGCAGCGAACTCGACCGGATGGTTGGCTCTGTCAATCACCAGGGGGTCGTTCTC
GAGACCAGTCCGTACCCGTACGTCGATTTCGCGACGTTACTCGACCCGGCACCGGAGAGCATCGTCCTCCTGCTCGACCA
TCTGCAGGATCCCCAGAATATCGCGACCTTGCTCCGCACTGCTGAGGCGGCTGGCGTGCGTGGGGTCGTCCTGCCGGAAC
GGCGCGCTGCTGGTATCACGCCGGCCGTGGTCAACGCTTCAGCCGGAGCTGTCGAGCACCTCCAGATCACACTCGTCACC
AACCTCGCTCGCGCGGTCGACACGCTCCGTGAGCACGGCTACTGGATCGTCGCCTTGGAACCGGGACCGAACGCCCAGTC
GCTTTTCCGGGCTCCCTTGCCACTCCCGCTGGTTCTGCTGGTCGGCGCTGAGGGGCATGGCCTCTCACCGGTTCTCCTCA
AACGAGCCGATGTACAAGTCATCATCCCGATGCTGGGACAAATCGAATCGCTCAATGCAGCCGTTGCCGGGTCGATCGCT
CTTTACGAGATTGTCCGTCGGCTGTTGGGACAGGAATCCGCCGAAAAAACCGAGACACGAGGTTGA

Upstream 100 bases:

>100_bases
CCCAGCGTCAATGGGAACTGGCGGACTACATTCGCGGTCGGCTCAACGAACTCGGCGTCCTCGTCGAGGATACACCGGGC
GGAACGACCTGGCGTTGGAC

Downstream 100 bases:

>100_bases
AAGGCAGGGTAGCCACCCGTCACGACGACCTCAGGCAGTCTCGGCGAAGAGCACGTCCCGCTTGCGTCCAGCTCCCCGCA
GCCCACTGCGGTTCTTGTAC

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRRLQPGRPSEYLYGRNAVAEALRGRRRHRRLFVASGIETHGRIVALMEAARVRGIPVIVIPRSELDRMVGSVNHQGVVL
ETSPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGVVLPERRAAGITPAVVNASAGAVEHLQITLVT
NLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLLVGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIA
LYEIVRRLLGQESAEKTETRG

Sequences:

>Translated_261_residues
MRRLQPGRPSEYLYGRNAVAEALRGRRRHRRLFVASGIETHGRIVALMEAARVRGIPVIVIPRSELDRMVGSVNHQGVVL
ETSPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGVVLPERRAAGITPAVVNASAGAVEHLQITLVT
NLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLLVGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIA
LYEIVRRLLGQESAEKTETRG
>Mature_261_residues
MRRLQPGRPSEYLYGRNAVAEALRGRRRHRRLFVASGIETHGRIVALMEAARVRGIPVIVIPRSELDRMVGSVNHQGVVL
ETSPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGVVLPERRAAGITPAVVNASAGAVEHLQITLVT
NLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLLVGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIA
LYEIVRRLLGQESAEKTETRG

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=263, Percent_Identity=30.4182509505703, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1790623, Length=242, Percent_Identity=33.4710743801653, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790083, Length=167, Percent_Identity=29.3413173652695, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788935, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555908, Length=261, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324775, Length=292, Percent_Identity=26.3698630136986, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28249; Mature: 28249

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLQPGRPSEYLYGRNAVAEALRGRRRHRRLFVASGIETHGRIVALMEAARVRGIPVIV
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEECCCCCCCHHHHEEHHHHHCCCCEEE
IPRSELDRMVGSVNHQGVVLETSPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRT
ECHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
AEAAGVRGVVLPERRAAGITPAVVNASAGAVEHLQITLVTNLARAVDTLREHGYWIVALE
HHHCCCCEEECCCHHCCCCCHHHCCCCCCCCHHEEEHHHHHHHHHHHHHHHCCEEEEEEC
PGPNAQSLFRAPLPLPLVLLVGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIA
CCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEHHHHHCCHHHCCHHHHHHHH
LYEIVRRLLGQESAEKTETRG
HHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MRRLQPGRPSEYLYGRNAVAEALRGRRRHRRLFVASGIETHGRIVALMEAARVRGIPVIV
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEECCCCCCCHHHHEEHHHHHCCCCEEE
IPRSELDRMVGSVNHQGVVLETSPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRT
ECHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
AEAAGVRGVVLPERRAAGITPAVVNASAGAVEHLQITLVTNLARAVDTLREHGYWIVALE
HHHCCCCEEECCCHHCCCCCHHHCCCCCCCCHHEEEHHHHHHHHHHHHHHHCCEEEEEEC
PGPNAQSLFRAPLPLPLVLLVGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIA
CCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEHHHHHCCHHHCCHHHHHHHH
LYEIVRRLLGQESAEKTETRG
HHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]