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The map label for this gene is gpmI

Identifier: 221632660

GI number: 221632660

Start: 634138

End: 635712

Strand: Reverse

Name: gpmI

Synonym: trd_0643

Alternate gene names: 221632660

Gene position: 635712-634138 (Counterclockwise)

Preceding gene: 221632662

Following gene: 221632658

Centisome position: 31.74

GC content: 62.16

Gene sequence:

>1575_bases
GTGGATCGACCGCCGATGGTTTGCCTCGTCGTCCTGGACGGCTGGGCGATCGGCCCGGACTATCCCGGCAATGCGATCCG
GGCTGCCCACACGCCGGTCATGGATCGTCTCCAAGCAACCTATCCGATGACGACACTCCGCTGCTGGGGTCGGGACGTCG
GCCTGCCCGATGACCAGATGGGAAACTCTGAGGTCGGACACCTCAATCTGGGTGCCGGGCGCATCGTCTATCAACTCATT
ACGCGTATCGATCTTGCGATCGAGGACGGTTCATTCTTCCAGAATGAGGCATTCCAGCGAGCACTCGACCGCGCGCGCCA
GCCGGGACGCACGCTCCATCTCATGGGCTTGATCGGTGATGGTGGCGTGCACAGCCATCAACGGCACCTTCTGGCCCTGT
TGGAACTCGCTGCTCGTGCTGGGATTTCCCGTGTCGCCGTCCATGCCTTTACCGACGGTCGGGATACCGCTCCGACGAGC
GGTATCGAACACCTGCGCGAGCTACTCGCCGCGCTGGATCGCCTCCGCACCGGTTTCGTCGCTACCGTGAGCGGTCGCTA
TTATGCGATGGACCGGGACAAGCGCTGGGAGCGGACCAAGCTCGCCTACGACGCCATCGTCTGTGGGCTCGGCCAAACCG
CGCGCTCGCCCCTCGAAGCGATCGAGCGAAGCTACGCACAGGGTATAACCGACGAGTTCATCGTCCCAACGGTCATCGTC
GATGCAGAAGGAAAGCCGCTCGCGACCATCAACGACGGGGATGCGGTCATCTTCTTCAATTTTCGCGCTGACCGCGCCCG
GCAGCTCACGCAAGCGCTCACTGATGCCGGCGGCTTCACTGCTTTCCCACGCTGTCGATGGCCTCGTGATCTCCTCATGG
TGACGATGGCCGAGTACGAACCCCACTTTCCTGTGCTCGTCGCCTTCGCCCCTGATATCGTCCGCGTTCCCCTCGCTCGA
GTACTCTCCGATGTTGGACTCCGGCAGTTCCACACCGCCGAGACGGAGAAATACGCGCATGTGACGTATTTCTTCAACGG
CGGCCGCGAAGAACCATTCCCCGGCGAGGATCGGCTCCTCGTCCCCTCACCCAAAGTACCCACCTACGACCTCAAGCCGG
AAATGAGTGCTCCCGAAGTGACCGATGCTGCGGTCCAGGCGATCGTTTCGCAACGCTACGCCTTCGTCCTCGTCAACTAC
GCCAATCCCGATATGGTCGGGCACACGGGTGTCTTCGCGGCCGCAGTCGCTGCGGTGGAGTGTGTCGACCGTTGTCTTGG
ACGCATCGAGCAGGCCGTGCGTTCGGTCAACGGCTATCTTGTCGTCACGGCTGACCACGGAAATGCCGACGAGATGCTGG
TTCCTGGAACCAACGAGGTTTGGACGGCGCATACGAAGAATCCGGTACCATTCATCCTCGTCGCACCGAACCATTCGCCA
TTTCGCTCGGTGGCTCTGCGGACCGGTGGGCGCCTAGCCGATGTCGCGCCGACGATCCTCGAGATCATGGGCCTTCCCCA
ACCGGAGGAAATGACCGGCCGGAGTTTGATCGTCGCACCATCCGTCGGCAGGTGA

Upstream 100 bases:

>100_bases
TGTACCGCGAGCGTTTCGCGAAGCGGTTTGTCAGGAATGCCAATGATGTCTACCATCAGCGCGAGGGTGATGGCACCCAT
CGACTGGGGAGGGGGCTCTT

Downstream 100 bases:

>100_bases
TCGGCGCGGGCTCGCTTCGCGTTGGTGAGCACCTCGAGCCGAATCGAGCGCGCGAGTCGTCATCATCAGTGTCGAACTGT
GCGGTCACATACCAGCCCCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MDRPPMVCLVVLDGWAIGPDYPGNAIRAAHTPVMDRLQATYPMTTLRCWGRDVGLPDDQMGNSEVGHLNLGAGRIVYQLI
TRIDLAIEDGSFFQNEAFQRALDRARQPGRTLHLMGLIGDGGVHSHQRHLLALLELAARAGISRVAVHAFTDGRDTAPTS
GIEHLRELLAALDRLRTGFVATVSGRYYAMDRDKRWERTKLAYDAIVCGLGQTARSPLEAIERSYAQGITDEFIVPTVIV
DAEGKPLATINDGDAVIFFNFRADRARQLTQALTDAGGFTAFPRCRWPRDLLMVTMAEYEPHFPVLVAFAPDIVRVPLAR
VLSDVGLRQFHTAETEKYAHVTYFFNGGREEPFPGEDRLLVPSPKVPTYDLKPEMSAPEVTDAAVQAIVSQRYAFVLVNY
ANPDMVGHTGVFAAAVAAVECVDRCLGRIEQAVRSVNGYLVVTADHGNADEMLVPGTNEVWTAHTKNPVPFILVAPNHSP
FRSVALRTGGRLADVAPTILEIMGLPQPEEMTGRSLIVAPSVGR

Sequences:

>Translated_524_residues
MDRPPMVCLVVLDGWAIGPDYPGNAIRAAHTPVMDRLQATYPMTTLRCWGRDVGLPDDQMGNSEVGHLNLGAGRIVYQLI
TRIDLAIEDGSFFQNEAFQRALDRARQPGRTLHLMGLIGDGGVHSHQRHLLALLELAARAGISRVAVHAFTDGRDTAPTS
GIEHLRELLAALDRLRTGFVATVSGRYYAMDRDKRWERTKLAYDAIVCGLGQTARSPLEAIERSYAQGITDEFIVPTVIV
DAEGKPLATINDGDAVIFFNFRADRARQLTQALTDAGGFTAFPRCRWPRDLLMVTMAEYEPHFPVLVAFAPDIVRVPLAR
VLSDVGLRQFHTAETEKYAHVTYFFNGGREEPFPGEDRLLVPSPKVPTYDLKPEMSAPEVTDAAVQAIVSQRYAFVLVNY
ANPDMVGHTGVFAAAVAAVECVDRCLGRIEQAVRSVNGYLVVTADHGNADEMLVPGTNEVWTAHTKNPVPFILVAPNHSP
FRSVALRTGGRLADVAPTILEIMGLPQPEEMTGRSLIVAPSVGR
>Mature_524_residues
MDRPPMVCLVVLDGWAIGPDYPGNAIRAAHTPVMDRLQATYPMTTLRCWGRDVGLPDDQMGNSEVGHLNLGAGRIVYQLI
TRIDLAIEDGSFFQNEAFQRALDRARQPGRTLHLMGLIGDGGVHSHQRHLLALLELAARAGISRVAVHAFTDGRDTAPTS
GIEHLRELLAALDRLRTGFVATVSGRYYAMDRDKRWERTKLAYDAIVCGLGQTARSPLEAIERSYAQGITDEFIVPTVIV
DAEGKPLATINDGDAVIFFNFRADRARQLTQALTDAGGFTAFPRCRWPRDLLMVTMAEYEPHFPVLVAFAPDIVRVPLAR
VLSDVGLRQFHTAETEKYAHVTYFFNGGREEPFPGEDRLLVPSPKVPTYDLKPEMSAPEVTDAAVQAIVSQRYAFVLVNY
ANPDMVGHTGVFAAAVAAVECVDRCLGRIEQAVRSVNGYLVVTADHGNADEMLVPGTNEVWTAHTKNPVPFILVAPNHSP
FRSVALRTGGRLADVAPTILEIMGLPQPEEMTGRSLIVAPSVGR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=518, Percent_Identity=48.4555984555985, Blast_Score=484, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI32564249, Length=519, Percent_Identity=46.242774566474, Blast_Score=447, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17507741, Length=519, Percent_Identity=46.242774566474, Blast_Score=447, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_THERP (B9KYT9)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002521881.1
- ProteinModelPortal:   B9KYT9
- GeneID:   7356014
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_0643
- OMA:   DNKTDEF
- ProtClustDB:   PRK05434
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 57422; Mature: 57422

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPPMVCLVVLDGWAIGPDYPGNAIRAAHTPVMDRLQATYPMTTLRCWGRDVGLPDDQM
CCCCCEEEEEEEECEECCCCCCCCCEEHHCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
GNSEVGHLNLGAGRIVYQLITRIDLAIEDGSFFQNEAFQRALDRARQPGRTLHLMGLIGD
CCCCCCEEECCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
GGVHSHQRHLLALLELAARAGISRVAVHAFTDGRDTAPTSGIEHLRELLAALDRLRTGFV
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
ATVSGRYYAMDRDKRWERTKLAYDAIVCGLGQTARSPLEAIERSYAQGITDEFIVPTVIV
EEECCEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCEECCEEEE
DAEGKPLATINDGDAVIFFNFRADRARQLTQALTDAGGFTAFPRCRWPRDLLMVTMAEYE
CCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
PHFPVLVAFAPDIVRVPLARVLSDVGLRQFHTAETEKYAHVTYFFNGGREEPFPGEDRLL
CCCCEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEE
VPSPKVPTYDLKPEMSAPEVTDAAVQAIVSQRYAFVLVNYANPDMVGHTGVFAAAVAAVE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
CVDRCLGRIEQAVRSVNGYLVVTADHGNADEMLVPGTNEVWTAHTKNPVPFILVAPNHSP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCEEEECCCCCCCEEEECCCCCC
FRSVALRTGGRLADVAPTILEIMGLPQPEEMTGRSLIVAPSVGR
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCC
>Mature Secondary Structure
MDRPPMVCLVVLDGWAIGPDYPGNAIRAAHTPVMDRLQATYPMTTLRCWGRDVGLPDDQM
CCCCCEEEEEEEECEECCCCCCCCCEEHHCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
GNSEVGHLNLGAGRIVYQLITRIDLAIEDGSFFQNEAFQRALDRARQPGRTLHLMGLIGD
CCCCCCEEECCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
GGVHSHQRHLLALLELAARAGISRVAVHAFTDGRDTAPTSGIEHLRELLAALDRLRTGFV
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
ATVSGRYYAMDRDKRWERTKLAYDAIVCGLGQTARSPLEAIERSYAQGITDEFIVPTVIV
EEECCEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCEECCEEEE
DAEGKPLATINDGDAVIFFNFRADRARQLTQALTDAGGFTAFPRCRWPRDLLMVTMAEYE
CCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
PHFPVLVAFAPDIVRVPLARVLSDVGLRQFHTAETEKYAHVTYFFNGGREEPFPGEDRLL
CCCCEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEE
VPSPKVPTYDLKPEMSAPEVTDAAVQAIVSQRYAFVLVNYANPDMVGHTGVFAAAVAAVE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
CVDRCLGRIEQAVRSVNGYLVVTADHGNADEMLVPGTNEVWTAHTKNPVPFILVAPNHSP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCEEEECCCCCCCEEEECCCCCC
FRSVALRTGGRLADVAPTILEIMGLPQPEEMTGRSLIVAPSVGR
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA