| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is gcvT [H]
Identifier: 221632450
GI number: 221632450
Start: 420997
End: 422406
Strand: Reverse
Name: gcvT [H]
Synonym: trd_0424
Alternate gene names: 221632450
Gene position: 422406-420997 (Counterclockwise)
Preceding gene: 221632460
Following gene: 221632449
Centisome position: 21.09
GC content: 66.24
Gene sequence:
>1410_bases ATGACCAGCGAAACACCGCGCACGCTGCAGGAGGTACTGGAGCGCGCACCGAGCGTGCAGGAGTTGCTCTACCACAACCC GACCGGCGCCCGGGTCTACCCCGTCGTCCCCCCTGAGTTCACCAACTGGCGGGACGAACAGCACGCCTGGCGGGATACCG TCTGCCTCTTCGACCTCTCCTACCACATGACGGACCTTTTCCTGCGTGGTCCCGATGCCTTCGCCCTCCTCCGCCAGCTC GGCATCAACTCCTTCGAGGGCTTCCAGCCCGGGCAGGCCAAGCAGTACGTCCCCGTCTCCCCCGAGGGGTACGTCATCGG CGACGTCATCCTCTTCTACCTGGAGGACGGTACTTTCCAGCTGGTCGGCCGCCCCTCTGTCCATAACTGGGTCCAGTTCC ACGCCGCGACCAGCGGTGCCGCCGTCTCCTTCGAGCGTGACGAGTGGTCGGTCACCGATCCCCACAAGCCGCGCAAGACC TTCCGCTTCCAGATCCAGGGCCCCAACGCCCCCATGCTCCTCGAGAAACTGCTCGGCGGCCCCCCACCCGACCTCCCCTT CTTCCACTTCACCCGCGTCTCGATCGCCGGCAAGCGCGTCAGCCTCCTCCACCACGGCATGAGCGGGGTGGCCGGCGCTG AGTTCTTCGGCGATTTCGCCGATGGCCCCGCCGTCAAGGCCGCCATCCTCGAAGCCGGCAAGGAGTTCGGCATCCGCCAT GTCGGTAGCCGCGCCTATGCGACCAACACATTGGAATCCGGCTGGATTCCCAATCCGCTGCCGGCGATCTACACCAGTCC GGCGCTCGAGGCCTACCGGCGGTGGCTCCCCGCGACGGCCTACGAAGCGATCGGCTCGCTGGGTGGAAGTTTCGTCAGTC CCCGGATCGAAGACTACTACCTGACCCCGTGGGATCTGGGGTATGGTCGCCTGATCAAGTTCGATCACGACTTCGTCGGC CGAGCCGCCCTCGAGCGGCTCAAGGACCAGCCACACCGCAAGAAGGTGACGCTGGTCTGGGATCCGGACGAGGCCGCGCG CGTCATCAGCAGTCTCGTCACGCACCCCAAGGGCCAGCGCTACAAGTACTTCGATCTCCCCTTGGCCCAGTACGCGACTT GGATGTACGACGCTGTCCTCAACGATGCTGGAGAAGTCGTCGGCTTTGCGATGTTCACCGGCTTCTCCTCGAACGAGGAG CGGGTGCTCTCGCTGGCGACGGTGCGCTCGGAGTATGCCCAGGAGGGGACGCGACTGCGCGTGGTCTGGGGAGAGCCGAA CGGGGGTTCGCGTAAGCCGTCGGTCGAGCGGCACGTGCAGACTGAGGTGTGGGTGACGGTCGGTCCCGCCCCCTACGCGG AACCAGCCCGCCGCTATCGCGAGCAAGTCGCCCGCGCCCGCCGGTCGTAA
Upstream 100 bases:
>100_bases AGAGCAGCTCGGGGGAAGGCTGTCCAGTTCACTGGACCGAGTCCCCTCTCTCTGAGTGCGGTTGGCACGGAGACCCGAAC AGCGAGGGAGGATCGCTTTC
Downstream 100 bases:
>100_bases CGGACGCGTACGACGCCAACCGAGTCTCGCCACGAGCCCCCGTGTTGCGCCGGGGGCTCGCTCTTCTCCGAACGATAAGA AGTGGGCTGGCAGAGCACGG
Product: putative aminomethyltransferase
Products: NA
Alternate protein names: Glycine cleavage system T protein [H]
Number of amino acids: Translated: 469; Mature: 468
Protein sequence:
>469_residues MTSETPRTLQEVLERAPSVQELLYHNPTGARVYPVVPPEFTNWRDEQHAWRDTVCLFDLSYHMTDLFLRGPDAFALLRQL GINSFEGFQPGQAKQYVPVSPEGYVIGDVILFYLEDGTFQLVGRPSVHNWVQFHAATSGAAVSFERDEWSVTDPHKPRKT FRFQIQGPNAPMLLEKLLGGPPPDLPFFHFTRVSIAGKRVSLLHHGMSGVAGAEFFGDFADGPAVKAAILEAGKEFGIRH VGSRAYATNTLESGWIPNPLPAIYTSPALEAYRRWLPATAYEAIGSLGGSFVSPRIEDYYLTPWDLGYGRLIKFDHDFVG RAALERLKDQPHRKKVTLVWDPDEAARVISSLVTHPKGQRYKYFDLPLAQYATWMYDAVLNDAGEVVGFAMFTGFSSNEE RVLSLATVRSEYAQEGTRLRVVWGEPNGGSRKPSVERHVQTEVWVTVGPAPYAEPARRYREQVARARRS
Sequences:
>Translated_469_residues MTSETPRTLQEVLERAPSVQELLYHNPTGARVYPVVPPEFTNWRDEQHAWRDTVCLFDLSYHMTDLFLRGPDAFALLRQL GINSFEGFQPGQAKQYVPVSPEGYVIGDVILFYLEDGTFQLVGRPSVHNWVQFHAATSGAAVSFERDEWSVTDPHKPRKT FRFQIQGPNAPMLLEKLLGGPPPDLPFFHFTRVSIAGKRVSLLHHGMSGVAGAEFFGDFADGPAVKAAILEAGKEFGIRH VGSRAYATNTLESGWIPNPLPAIYTSPALEAYRRWLPATAYEAIGSLGGSFVSPRIEDYYLTPWDLGYGRLIKFDHDFVG RAALERLKDQPHRKKVTLVWDPDEAARVISSLVTHPKGQRYKYFDLPLAQYATWMYDAVLNDAGEVVGFAMFTGFSSNEE RVLSLATVRSEYAQEGTRLRVVWGEPNGGSRKPSVERHVQTEVWVTVGPAPYAEPARRYREQVARARRS >Mature_468_residues TSETPRTLQEVLERAPSVQELLYHNPTGARVYPVVPPEFTNWRDEQHAWRDTVCLFDLSYHMTDLFLRGPDAFALLRQLG INSFEGFQPGQAKQYVPVSPEGYVIGDVILFYLEDGTFQLVGRPSVHNWVQFHAATSGAAVSFERDEWSVTDPHKPRKTF RFQIQGPNAPMLLEKLLGGPPPDLPFFHFTRVSIAGKRVSLLHHGMSGVAGAEFFGDFADGPAVKAAILEAGKEFGIRHV GSRAYATNTLESGWIPNPLPAIYTSPALEAYRRWLPATAYEAIGSLGGSFVSPRIEDYYLTPWDLGYGRLIKFDHDFVGR AALERLKDQPHRKKVTLVWDPDEAARVISSLVTHPKGQRYKYFDLPLAQYATWMYDAVLNDAGEVVGFAMFTGFSSNEER VLSLATVRSEYAQEGTRLRVVWGEPNGGSRKPSVERHVQTEVWVTVGPAPYAEPARRYREQVARARRS
Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]
COG id: COG0404
COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the gcvT family [H]
Homologues:
None
Paralogues:
None
Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013977 - InterPro: IPR006222 - InterPro: IPR006223 - InterPro: IPR022903 [H]
Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]
EC number: =2.1.2.10 [H]
Molecular weight: Translated: 52701; Mature: 52570
Theoretical pI: Translated: 7.06; Mature: 7.06
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSETPRTLQEVLERAPSVQELLYHNPTGARVYPVVPPEFTNWRDEQHAWRDTVCLFDLS CCCCCHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCEEEEEECH YHMTDLFLRGPDAFALLRQLGINSFEGFQPGQAKQYVPVSPEGYVIGDVILFYLEDGTFQ HHHHHHEEECCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEEEECCEEE LVGRPSVHNWVQFHAATSGAAVSFERDEWSVTDPHKPRKTFRFQIQGPNAPMLLEKLLGG EEECCCHHHHHEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCC PPPDLPFFHFTRVSIAGKRVSLLHHGMSGVAGAEFFGDFADGPAVKAAILEAGKEFGIRH CCCCCCCEEEEEEEECCHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCHHH VGSRAYATNTLESGWIPNPLPAIYTSPALEAYRRWLPATAYEAIGSLGGSFVSPRIEDYY CCCCHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEE LTPWDLGYGRLIKFDHDFVGRAALERLKDQPHRKKVTLVWDPDEAARVISSLVTHPKGQR ECCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC YKYFDLPLAQYATWMYDAVLNDAGEVVGFAMFTGFSSNEERVLSLATVRSEYAQEGTRLR EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEE VVWGEPNGGSRKPSVERHVQTEVWVTVGPAPYAEPARRYREQVARARRS EEEECCCCCCCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC >Mature Secondary Structure TSETPRTLQEVLERAPSVQELLYHNPTGARVYPVVPPEFTNWRDEQHAWRDTVCLFDLS CCCCHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCEEEEEECH YHMTDLFLRGPDAFALLRQLGINSFEGFQPGQAKQYVPVSPEGYVIGDVILFYLEDGTFQ HHHHHHEEECCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEEEECCEEE LVGRPSVHNWVQFHAATSGAAVSFERDEWSVTDPHKPRKTFRFQIQGPNAPMLLEKLLGG EEECCCHHHHHEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCC PPPDLPFFHFTRVSIAGKRVSLLHHGMSGVAGAEFFGDFADGPAVKAAILEAGKEFGIRH CCCCCCCEEEEEEEECCHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCHHH VGSRAYATNTLESGWIPNPLPAIYTSPALEAYRRWLPATAYEAIGSLGGSFVSPRIEDYY CCCCHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEE LTPWDLGYGRLIKFDHDFVGRAALERLKDQPHRKKVTLVWDPDEAARVISSLVTHPKGQR ECCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC YKYFDLPLAQYATWMYDAVLNDAGEVVGFAMFTGFSSNEERVLSLATVRSEYAQEGTRLR EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEE VVWGEPNGGSRKPSVERHVQTEVWVTVGPAPYAEPARRYREQVARARRS EEEECCCCCCCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA