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The map label for this gene is dapB

Identifier: 221632441

GI number: 221632441

Start: 412021

End: 412797

Strand: Reverse

Name: dapB

Synonym: trd_0413

Alternate gene names: 221632441

Gene position: 412797-412021 (Counterclockwise)

Preceding gene: 221632442

Following gene: 221632440

Centisome position: 20.61

GC content: 68.98

Gene sequence:

>777_bases
ATGCTCCGCCTCGCGCTCACCGGTGTCACCGGACGAATGGGACGCGCTGTCCTCGAACTGGCCGCGAGCGCTCCGGATAT
TCAGCTCGTATGTGGGCTCATCCGTCCAGCGCGTGATCCCCACGAGGTCGCTGCACAGCTCCCAGCACCTCTCGCGCTCA
CCAGCCGAGTGGCCGAACTCGTCCAGGGAGCTGATGTGGTGGTCGACTTCAGTCATCCGGCCGTGACCGTAGCGGTCGCG
GAGGCCGCAGCGCACGCGGGTATCCCGCTGGTGAGCGGGACGACCGGCTTGAGCGAACACGACCAGGCGGTCATCCTCCG
GGCCGCCCAGCACGTTCCTGTCGTCCAGGCCGCCAACTTCAGCCTCGGCATCGCTCTCTTGCACTGGCTTCTCCCCGAAC
TCGTCGCGCGCTTGCCGACCTGGGATGTCGAACTGATCGAGCGGCACCATCGGCACAAGCGAGATGCTCCTTCCGGGACG
GCGCTCGCGCTGGCACGAACACTGCTCGCCGCGCGCGAGCCCGCTCCCAGCCCGCTGGTCTACGGCCGCGGGCCGGGGAC
CGCCCCTCGCCAACCCGGCGAAGTCGGCATCCATGCCGTCCGTGCCGGTGGCGAAGTCGGTCGGCACACTGTCCTGCTGG
CGACCGACGACGAGGCGATCGAGGTGACCCACTGGGTGCAGAGTCGCCGGGCCTACGCGCAGGGTGCCCTCGAAGCAGCG
CGCCGGCTCATCGGCCGACCACCTGGACTGTACAGCCTGCAGGATCTCGTCACCTGA

Upstream 100 bases:

>100_bases
CACCGCTGGCTCCGGCCAACCGCGAGCGGCTGCTCGCTGCGCTGGCCAGCTGTCCACACACTGCTTCGCTTCTCGCACGA
CCGATGGGGGAGGCTGCGTG

Downstream 100 bases:

>100_bases
GTGACCATGGGCGGCCAAGCTCCGCAAACTGCTCTCGGCCGCCCATAGCCAAGGGAACCGATCCGCGGTAGCATGATTCG
CGAGAACGGACCCTGAATCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLRLALTGVTGRMGRAVLELAASAPDIQLVCGLIRPARDPHEVAAQLPAPLALTSRVAELVQGADVVVDFSHPAVTVAVA
EAAAHAGIPLVSGTTGLSEHDQAVILRAAQHVPVVQAANFSLGIALLHWLLPELVARLPTWDVELIERHHRHKRDAPSGT
ALALARTLLAAREPAPSPLVYGRGPGTAPRQPGEVGIHAVRAGGEVGRHTVLLATDDEAIEVTHWVQSRRAYAQGALEAA
RRLIGRPPGLYSLQDLVT

Sequences:

>Translated_258_residues
MLRLALTGVTGRMGRAVLELAASAPDIQLVCGLIRPARDPHEVAAQLPAPLALTSRVAELVQGADVVVDFSHPAVTVAVA
EAAAHAGIPLVSGTTGLSEHDQAVILRAAQHVPVVQAANFSLGIALLHWLLPELVARLPTWDVELIERHHRHKRDAPSGT
ALALARTLLAAREPAPSPLVYGRGPGTAPRQPGEVGIHAVRAGGEVGRHTVLLATDDEAIEVTHWVQSRRAYAQGALEAA
RRLIGRPPGLYSLQDLVT
>Mature_258_residues
MLRLALTGVTGRMGRAVLELAASAPDIQLVCGLIRPARDPHEVAAQLPAPLALTSRVAELVQGADVVVDFSHPAVTVAVA
EAAAHAGIPLVSGTTGLSEHDQAVILRAAQHVPVVQAANFSLGIALLHWLLPELVARLPTWDVELIERHHRHKRDAPSGT
ALALARTLLAAREPAPSPLVYGRGPGTAPRQPGEVGIHAVRAGGEVGRHTVLLATDDEAIEVTHWVQSRRAYAQGALEAA
RRLIGRPPGLYSLQDLVT

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=35.361216730038, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_THERP (B9KY70)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002521662.1
- GeneID:   7356048
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_0413
- OMA:   GALKACE
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27219; Mature: 27219

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLALTGVTGRMGRAVLELAASAPDIQLVCGLIRPARDPHEVAAQLPAPLALTSRVAEL
CEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
VQGADVVVDFSHPAVTVAVAEAAAHAGIPLVSGTTGLSEHDQAVILRAAQHVPVVQAANF
HCCCCEEEECCCCEEEHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEECCC
SLGIALLHWLLPELVARLPTWDVELIERHHRHKRDAPSGTALALARTLLAAREPAPSPLV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEE
YGRGPGTAPRQPGEVGIHAVRAGGEVGRHTVLLATDDEAIEVTHWVQSRRAYAQGALEAA
ECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RRLIGRPPGLYSLQDLVT
HHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MLRLALTGVTGRMGRAVLELAASAPDIQLVCGLIRPARDPHEVAAQLPAPLALTSRVAEL
CEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
VQGADVVVDFSHPAVTVAVAEAAAHAGIPLVSGTTGLSEHDQAVILRAAQHVPVVQAANF
HCCCCEEEECCCCEEEHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEECCC
SLGIALLHWLLPELVARLPTWDVELIERHHRHKRDAPSGTALALARTLLAAREPAPSPLV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEE
YGRGPGTAPRQPGEVGIHAVRAGGEVGRHTVLLATDDEAIEVTHWVQSRRAYAQGALEAA
ECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RRLIGRPPGLYSLQDLVT
HHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA