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The map label for this gene is csd [H]

Identifier: 221632419

GI number: 221632419

Start: 391527

End: 392723

Strand: Reverse

Name: csd [H]

Synonym: trd_0391

Alternate gene names: 221632419

Gene position: 392723-391527 (Counterclockwise)

Preceding gene: 221632420

Following gene: 221632418

Centisome position: 19.61

GC content: 65.16

Gene sequence:

>1197_bases
ATGCAGGAATCCGACAAAGTCGCAGCGATCCGCGCAGCCATGCCAGCGGTCCGCGAGTACGTCTATCTCAATACCGGCAC
CTTCGGCCCCTTACCCACTCTCGTCCAGGAAGCGATGCAGCGAGAAGCGGAGCGAGAATTCCTGCATGGCCGCATCACCA
GCGAGAGCTACGAGCGGGCCACTGACCTCAAGCGTCGGGCTCGCGAGGAAGTCGCTCGCTTGCTCGGTTGTCGCCCTGAC
CAGATCGCGCTCACGCGCCACACCACGGACGGGATCAATCTCGCCGTCATGGGTCTCGACTGGCAACCGGGCGACGAGAT
CGTGACCACCGACATGGAGCATCCCGGCGCCCAGGGACCGGTCTTCAATGTCGCCCGGCGCTATGGAGTGGTAGTTAGAA
CGGCCAGACTCGGCACTGGAGCAGGCGACGTCGCGGGTACGCTCGCTCGCCTGATCGGCCGGCGAACACGCATGGTCGTA
CTCTCTCATCTCACGTGGAATACCGGCGCCATCCTGCCCATCGCGGAGATCGCGACGCTCGCGCACCAGCACGGTGCGCT
GATCGTGGTCGATGGCGCACAGTCAGCCGGCTCCATCCCGACCGATGTCCGCGCACTCGGTGCGGATGTCTATGCCATCC
CTGGGCAGAAGTGGCTCTGTGGACCGGAAGGCACCGGCGCGGTCTACTTCTCCGACGAGGCGCTCGATCGCCTGCAGCTG
ACGATCGTCGGCTACGCCTCGCTCGCTCCCAACGGATTGGAGCCGATCGGCGGCTACTTCCTTCCCAAACCCACCGCTGA
GCGCTTCGAGGTCGGAGGCGTCAATGTTCCCGCGATCGCTGGCCAGGTCGCTGCCCTCCGCTGGTTACGCGAAGACATCG
GATACAGCTGGATTTTCCAGCGCGTGGCTGCCCTCGGCCGAAGAGCCGCCGACCGACTGGCCAGTCTCGATGGAGTCGAC
GTTCTCACTCCGCCTGACCGCATGGCTGGACTCGTGAGCTTCACGGTGCGCGACGGCGATCCGCAGGCGCTCGTCGCTGC
ATTGGCCCAACGCAACGTCATCGTCCGCTGGATCACGCACCCCTACAGCCTGCGCGTTTCGACCGGTTTCTACAACACCG
AAGACGACATCGAGCGGCTCGTCGACGCACTCGAAGACGCCCGGCGAGCCACCGCCGCCTCGCGGAGCATGGTGTGA

Upstream 100 bases:

>100_bases
TGACCAGTTCGTTCGGCGAGTGCTCAGGCTTGACGGATGCCGATCAGCGCAGTACACAGCCACTGTCGGCACGGGATGGC
CCGGAACAGGAGCGTGAGCG

Downstream 100 bases:

>100_bases
TGAACGAGCGGACCCCACCGACCTGGCCAGCTGGACACCGCGCGGCACTCGTCGTCTCCATCGACGTGGATGGTGAGTAC
GGCGTCATCGCTCAACATGG

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MQESDKVAAIRAAMPAVREYVYLNTGTFGPLPTLVQEAMQREAEREFLHGRITSESYERATDLKRRAREEVARLLGCRPD
QIALTRHTTDGINLAVMGLDWQPGDEIVTTDMEHPGAQGPVFNVARRYGVVVRTARLGTGAGDVAGTLARLIGRRTRMVV
LSHLTWNTGAILPIAEIATLAHQHGALIVVDGAQSAGSIPTDVRALGADVYAIPGQKWLCGPEGTGAVYFSDEALDRLQL
TIVGYASLAPNGLEPIGGYFLPKPTAERFEVGGVNVPAIAGQVAALRWLREDIGYSWIFQRVAALGRRAADRLASLDGVD
VLTPPDRMAGLVSFTVRDGDPQALVAALAQRNVIVRWITHPYSLRVSTGFYNTEDDIERLVDALEDARRATAASRSMV

Sequences:

>Translated_398_residues
MQESDKVAAIRAAMPAVREYVYLNTGTFGPLPTLVQEAMQREAEREFLHGRITSESYERATDLKRRAREEVARLLGCRPD
QIALTRHTTDGINLAVMGLDWQPGDEIVTTDMEHPGAQGPVFNVARRYGVVVRTARLGTGAGDVAGTLARLIGRRTRMVV
LSHLTWNTGAILPIAEIATLAHQHGALIVVDGAQSAGSIPTDVRALGADVYAIPGQKWLCGPEGTGAVYFSDEALDRLQL
TIVGYASLAPNGLEPIGGYFLPKPTAERFEVGGVNVPAIAGQVAALRWLREDIGYSWIFQRVAALGRRAADRLASLDGVD
VLTPPDRMAGLVSFTVRDGDPQALVAALAQRNVIVRWITHPYSLRVSTGFYNTEDDIERLVDALEDARRATAASRSMV
>Mature_398_residues
MQESDKVAAIRAAMPAVREYVYLNTGTFGPLPTLVQEAMQREAEREFLHGRITSESYERATDLKRRAREEVARLLGCRPD
QIALTRHTTDGINLAVMGLDWQPGDEIVTTDMEHPGAQGPVFNVARRYGVVVRTARLGTGAGDVAGTLARLIGRRTRMVV
LSHLTWNTGAILPIAEIATLAHQHGALIVVDGAQSAGSIPTDVRALGADVYAIPGQKWLCGPEGTGAVYFSDEALDRLQL
TIVGYASLAPNGLEPIGGYFLPKPTAERFEVGGVNVPAIAGQVAALRWLREDIGYSWIFQRVAALGRRAADRLASLDGVD
VLTPPDRMAGLVSFTVRDGDPQALVAALAQRNVIVRWITHPYSLRVSTGFYNTEDDIERLVDALEDARRATAASRSMV

Specific function: Catalyzes The Removal Of Elemental Sulfur And Selenium Atoms From L-Cysteine, L-Cystine, L-Selenocysteine, And L- Selenocystine To Produce L-Alanine. L-Cysteine Sulfinic Acid Is The Best Substrate. Functions As A Selenium Delivery Protein In The Pathway F

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789175, Length=400, Percent_Identity=30.5, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787970, Length=415, Percent_Identity=27.9518072289157, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI48994898, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25143064, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129463, Length=184, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43146; Mature: 43146

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESDKVAAIRAAMPAVREYVYLNTGTFGPLPTLVQEAMQREAEREFLHGRITSESYERA
CCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
TDLKRRAREEVARLLGCRPDQIALTRHTTDGINLAVMGLDWQPGDEIVTTDMEHPGAQGP
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCC
VFNVARRYGVVVRTARLGTGAGDVAGTLARLIGRRTRMVVLSHLTWNTGAILPIAEIATL
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHH
AHQHGALIVVDGAQSAGSIPTDVRALGADVYAIPGQKWLCGPEGTGAVYFSDEALDRLQL
HHHCCCEEEEECCCCCCCCCHHHHHHCCCEEEECCCCEEECCCCCCEEEECHHHHCCEEE
TIVGYASLAPNGLEPIGGYFLPKPTAERFEVGGVNVPAIAGQVAALRWLREDIGYSWIFQ
EEEEEHHCCCCCCCCCCCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHH
RVAALGRRAADRLASLDGVDVLTPPDRMAGLVSFTVRDGDPQALVAALAQRNVIVRWITH
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCHHHHHHHHHHCCEEEEEECC
PYSLRVSTGFYNTEDDIERLVDALEDARRATAASRSMV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQESDKVAAIRAAMPAVREYVYLNTGTFGPLPTLVQEAMQREAEREFLHGRITSESYERA
CCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
TDLKRRAREEVARLLGCRPDQIALTRHTTDGINLAVMGLDWQPGDEIVTTDMEHPGAQGP
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCC
VFNVARRYGVVVRTARLGTGAGDVAGTLARLIGRRTRMVVLSHLTWNTGAILPIAEIATL
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHH
AHQHGALIVVDGAQSAGSIPTDVRALGADVYAIPGQKWLCGPEGTGAVYFSDEALDRLQL
HHHCCCEEEEECCCCCCCCCHHHHHHCCCEEEECCCCEEECCCCCCEEEECHHHHCCEEE
TIVGYASLAPNGLEPIGGYFLPKPTAERFEVGGVNVPAIAGQVAALRWLREDIGYSWIFQ
EEEEEHHCCCCCCCCCCCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHH
RVAALGRRAADRLASLDGVDVLTPPDRMAGLVSFTVRDGDPQALVAALAQRNVIVRWITH
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCHHHHHHHHHHCCEEEEEECC
PYSLRVSTGFYNTEDDIERLVDALEDARRATAASRSMV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]