Click here to switch to the map view.

The map label for this gene is metX [H]

Identifier: 221632396

GI number: 221632396

Start: 370374

End: 371618

Strand: Reverse

Name: metX [H]

Synonym: trd_0368

Alternate gene names: 221632396

Gene position: 371618-370374 (Counterclockwise)

Preceding gene: 221632397

Following gene: 221632394

Centisome position: 18.55

GC content: 61.77

Gene sequence:

>1245_bases
TTGCGACGACGCAAGCCCCTCCACCATGTCGTGGGGGGTCTTCCTTTCAGTCCCTCCACGCAAGTCGATGAGGTCGTGAC
GGGAGCGAGTGGAGCAGGTCGCTTCCACGACGTGCCCGAGGGAGGGATTCCTGTGACGTCCACTCTGCCTGTGACGTACC
AGATTGCACGGATCGCCACACCCGAACAGCCTTTTGTGACCGAGCATGGCGACGTCTTGCCGGTCGTGGATATCGCGTAC
GAGACATGGGGAACTCTGAGCCCTACCGGTGACAATGTCGTCCTCATCTGCCATGCCCTGACTGGGAGCAGTCATGTCGC
GCCGCATGGCCCGGGTGATCAACCAGGCTGGTGGGATCCCATGGTCGGCCCCGGCCGCTTCATCGACACGGACCGGTACT
TCGTCATCTGTGCCAACGTGCTCGGGAGCTGTTACGGCTCGACCGGTCCGCGTTCGATCGATCCCCGCACCAGCCGTCGC
TACAACCTTCGCTTCCCCCTCATTACCGTTCGCGATATCGTCCGCTCCCAGGCGATGCTCCTGGACCAACTCGGGATCGA
GCGGGTCTATGCCGTGATCGGTGGCTCGCTCGGCGGTATGCAGGTACTGGAGTGGGCAGCGATGTATTCGGACCGAGTGG
AGCGGATCGTTCCCATTGCTGCTGGCGCCTCTTTTTCCGACCAAGGCATCGCCTATAACGAGGTCCAGCGGCGTGTCATC
ATGCTCGACCCAGCATGGCAGAACGGGGAGTACGAGGATGGAGAGGGTCCACGCTATGGACTGGCGATCGCTCGTATGCT
CGGCATGATCACCTATCAGTCCGACGAGCTCATGTCAGCCCGCTTCCAACGCCGGACAGGAGCACGCTACACCGAGTGGC
CCGAGTTCCTCGGACGCTACGACGTCGAGGGCTATCTCCACTACCAGGGTGACAAGCTCGTGCGCCGCTTCGATGCGAAC
AGCTACCTCTACCTCACTCGCGCTATGGATTCCCACGATCTGGGCCGTGGCCGAGGTGGCTATCACGCTGGACTCTCCCG
AATCCGTGCCCGAACGCTCGCCATCGGTATCCGCTCGGATATCCTCTTCTGGCCCAATCAGGTGAGAAGTCTCGCCGAAG
ACTTGCGTGCGCTCGGCGTCGATGCTCGCTATTGGGAACTCGACTCCCCCAACGGGCATGATGCCTTTCTCAAAGACTTC
GACCAGATCGGGCCAGTGATCGCGGCCTTCCTCGCCGAGCCCTAA

Upstream 100 bases:

>100_bases
TGGAGGGAACGGCCCGACGAAACCCGGCAACCAGCGCAGGCCACTGCGCCAGGTGCCAATGCCGGCGGAGCGGGAAAGCT
CCGCACGATGAGCGCGGTCC

Downstream 100 bases:

>100_bases
AAGCTATACCGAAACTGCCTGCGCGCGCTGCCCGCGAGCAGCATCGCGACGCGCCCCGACGAGCTGGACAGCGGTGTCCA
GCTCGTCGGTTTTCTCCTGT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRRRKPLHHVVGGLPFSPSTQVDEVVTGASGAGRFHDVPEGGIPVTSTLPVTYQIARIATPEQPFVTEHGDVLPVVDIAY
ETWGTLSPTGDNVVLICHALTGSSHVAPHGPGDQPGWWDPMVGPGRFIDTDRYFVICANVLGSCYGSTGPRSIDPRTSRR
YNLRFPLITVRDIVRSQAMLLDQLGIERVYAVIGGSLGGMQVLEWAAMYSDRVERIVPIAAGASFSDQGIAYNEVQRRVI
MLDPAWQNGEYEDGEGPRYGLAIARMLGMITYQSDELMSARFQRRTGARYTEWPEFLGRYDVEGYLHYQGDKLVRRFDAN
SYLYLTRAMDSHDLGRGRGGYHAGLSRIRARTLAIGIRSDILFWPNQVRSLAEDLRALGVDARYWELDSPNGHDAFLKDF
DQIGPVIAAFLAEP

Sequences:

>Translated_414_residues
MRRRKPLHHVVGGLPFSPSTQVDEVVTGASGAGRFHDVPEGGIPVTSTLPVTYQIARIATPEQPFVTEHGDVLPVVDIAY
ETWGTLSPTGDNVVLICHALTGSSHVAPHGPGDQPGWWDPMVGPGRFIDTDRYFVICANVLGSCYGSTGPRSIDPRTSRR
YNLRFPLITVRDIVRSQAMLLDQLGIERVYAVIGGSLGGMQVLEWAAMYSDRVERIVPIAAGASFSDQGIAYNEVQRRVI
MLDPAWQNGEYEDGEGPRYGLAIARMLGMITYQSDELMSARFQRRTGARYTEWPEFLGRYDVEGYLHYQGDKLVRRFDAN
SYLYLTRAMDSHDLGRGRGGYHAGLSRIRARTLAIGIRSDILFWPNQVRSLAEDLRALGVDARYWELDSPNGHDAFLKDF
DQIGPVIAAFLAEP
>Mature_414_residues
MRRRKPLHHVVGGLPFSPSTQVDEVVTGASGAGRFHDVPEGGIPVTSTLPVTYQIARIATPEQPFVTEHGDVLPVVDIAY
ETWGTLSPTGDNVVLICHALTGSSHVAPHGPGDQPGWWDPMVGPGRFIDTDRYFVICANVLGSCYGSTGPRSIDPRTSRR
YNLRFPLITVRDIVRSQAMLLDQLGIERVYAVIGGSLGGMQVLEWAAMYSDRVERIVPIAAGASFSDQGIAYNEVQRRVI
MLDPAWQNGEYEDGEGPRYGLAIARMLGMITYQSDELMSARFQRRTGARYTEWPEFLGRYDVEGYLHYQGDKLVRRFDAN
SYLYLTRAMDSHDLGRGRGGYHAGLSRIRARTLAIGIRSDILFWPNQVRSLAEDLRALGVDARYWELDSPNGHDAFLKDF
DQIGPVIAAFLAEP

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=230, Percent_Identity=44.3478260869565, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 45973; Mature: 45973

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRKPLHHVVGGLPFSPSTQVDEVVTGASGAGRFHDVPEGGIPVTSTLPVTYQIARIAT
CCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEECCC
PEQPFVTEHGDVLPVVDIAYETWGTLSPTGDNVVLICHALTGSSHVAPHGPGDQPGWWDP
CCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
MVGPGRFIDTDRYFVICANVLGSCYGSTGPRSIDPRTSRRYNLRFPLITVRDIVRSQAML
CCCCCCEECCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
LDQLGIERVYAVIGGSLGGMQVLEWAAMYSDRVERIVPIAAGASFSDQGIAYNEVQRRVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHCCEEE
MLDPAWQNGEYEDGEGPRYGLAIARMLGMITYQSDELMSARFQRRTGARYTEWPEFLGRY
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCC
DVEGYLHYQGDKLVRRFDANSYLYLTRAMDSHDLGRGRGGYHAGLSRIRARTLAIGIRSD
CCCEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCC
ILFWPNQVRSLAEDLRALGVDARYWELDSPNGHDAFLKDFDQIGPVIAAFLAEP
EEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRRKPLHHVVGGLPFSPSTQVDEVVTGASGAGRFHDVPEGGIPVTSTLPVTYQIARIAT
CCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEECCC
PEQPFVTEHGDVLPVVDIAYETWGTLSPTGDNVVLICHALTGSSHVAPHGPGDQPGWWDP
CCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
MVGPGRFIDTDRYFVICANVLGSCYGSTGPRSIDPRTSRRYNLRFPLITVRDIVRSQAML
CCCCCCEECCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
LDQLGIERVYAVIGGSLGGMQVLEWAAMYSDRVERIVPIAAGASFSDQGIAYNEVQRRVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHCCEEE
MLDPAWQNGEYEDGEGPRYGLAIARMLGMITYQSDELMSARFQRRTGARYTEWPEFLGRY
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCC
DVEGYLHYQGDKLVRRFDANSYLYLTRAMDSHDLGRGRGGYHAGLSRIRARTLAIGIRSD
CCCEEEEECCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCC
ILFWPNQVRSLAEDLRALGVDARYWELDSPNGHDAFLKDFDQIGPVIAAFLAEP
EEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA