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The map label for this gene is asd [H]

Identifier: 221632394

GI number: 221632394

Start: 367919

End: 368971

Strand: Reverse

Name: asd [H]

Synonym: trd_0366

Alternate gene names: 221632394

Gene position: 368971-367919 (Counterclockwise)

Preceding gene: 221632396

Following gene: 221632390

Centisome position: 18.42

GC content: 63.82

Gene sequence:

>1053_bases
GTGTCCGATCGAATCGACGTCGCCATCCTAGCGGCAACCGGTAGCGTCGGCCAGCGCTTCGTCCAACTCCTCGCTGGCCA
CCCCTGGTTCCGGATCGCTGAACTCGTCGCGAGCGACCGCTCGGCCGGGAAGCGCTATGCGGAAGCGGTGAACTGGCGCA
TCAGCGCTGCCCCGCCAGAAGAAGTGCGCGATCTTGTGGTGAAGCACATCGAAGAACCGATCAACAGCCCGATCGTCTTC
TCGGCCCTTCCCGGTGGGGTCGCTGGGCCGATCGAGGAGGCGTTGGCCGCTGAAGGAAAGAAGGTGTTCACGAACGCGCG
CGACCATCGGATGGATCCGGATGTGCCCCTTCTCATCCCCGAGGTGAACCCCGATCATGCCCGGGCGATCGAGCGACAGC
GGCAGCTCCGCGGATGGCGCGAGGGGTTCATCGTGGCCAACCCCAACTGCTCGACGATCCATCTCGTCCTCGCACTCAAG
CCGATTCACGATGCGTTCGGGATCGAGCGAGGCATCGTCACCACACTCCAGGCATCCTCGGGTGCCGGCTATCCTGGTGT
TCCTTCACTCGATCTGATCGATAACGTCATCCCGTACATCGGTGGAGAAGAAGAAAAGATCGAGGCCGAATCACGTAAGA
TCCTCGGTCGCTGGATCGACGGTACCTTCGAGGACGCTCCGATCGTGCTCAGTGCGCACTGCAATCGAGTCCCCGTGCGC
GACGGACACCTGGAGACCGTGAGCCTGGATCTCCATCGTTCGGCGACCCCGGCGGAGGTAATCGACGTGCTGCGAGCGTT
CCGTGCGCTTCCACAGGAACTGGAACTCCCCAGTGCTCCCCGTCACCCCGTCATCGTGCTCGAGGAGCCCGACCGGCCGC
AGCCGGTGCTCGACCGAGACGCCGAACGTGGTATGGCATCGGTCGTCGGCCGGGTTCGGCCTTGCTCGGTGTTCGACATC
CGGTTCGTCGTCCTCGGCCACAACACGATCCGCGGAGCCGCCGGAGCCTCGGTCTTGAACGCCGAGCTTTTCTACCGCGA
AGGGTTGCTCTAG

Upstream 100 bases:

>100_bases
GGGAGTCCGTAACGCGCGGCCGAACTCGAGCGAATGCCGGCAGGGGTTGCGACCTCTGCCGGTTTTGTTGTATCGGCACC
ACCAGTGAAGGGAGGAACTC

Downstream 100 bases:

>100_bases
GACGCAACCGAGAGCGCGGCAGGGCGCGCCCTGCCGCGCTCTCGCTCACGAAACAGCTGATACGAGCTCAGGAATGCGAG
CGGCGAGTTCTGGCCGGGTC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSDRIDVAILAATGSVGQRFVQLLAGHPWFRIAELVASDRSAGKRYAEAVNWRISAAPPEEVRDLVVKHIEEPINSPIVF
SALPGGVAGPIEEALAAEGKKVFTNARDHRMDPDVPLLIPEVNPDHARAIERQRQLRGWREGFIVANPNCSTIHLVLALK
PIHDAFGIERGIVTTLQASSGAGYPGVPSLDLIDNVIPYIGGEEEKIEAESRKILGRWIDGTFEDAPIVLSAHCNRVPVR
DGHLETVSLDLHRSATPAEVIDVLRAFRALPQELELPSAPRHPVIVLEEPDRPQPVLDRDAERGMASVVGRVRPCSVFDI
RFVVLGHNTIRGAAGASVLNAELFYREGLL

Sequences:

>Translated_350_residues
MSDRIDVAILAATGSVGQRFVQLLAGHPWFRIAELVASDRSAGKRYAEAVNWRISAAPPEEVRDLVVKHIEEPINSPIVF
SALPGGVAGPIEEALAAEGKKVFTNARDHRMDPDVPLLIPEVNPDHARAIERQRQLRGWREGFIVANPNCSTIHLVLALK
PIHDAFGIERGIVTTLQASSGAGYPGVPSLDLIDNVIPYIGGEEEKIEAESRKILGRWIDGTFEDAPIVLSAHCNRVPVR
DGHLETVSLDLHRSATPAEVIDVLRAFRALPQELELPSAPRHPVIVLEEPDRPQPVLDRDAERGMASVVGRVRPCSVFDI
RFVVLGHNTIRGAAGASVLNAELFYREGLL
>Mature_349_residues
SDRIDVAILAATGSVGQRFVQLLAGHPWFRIAELVASDRSAGKRYAEAVNWRISAAPPEEVRDLVVKHIEEPINSPIVFS
ALPGGVAGPIEEALAAEGKKVFTNARDHRMDPDVPLLIPEVNPDHARAIERQRQLRGWREGFIVANPNCSTIHLVLALKP
IHDAFGIERGIVTTLQASSGAGYPGVPSLDLIDNVIPYIGGEEEKIEAESRKILGRWIDGTFEDAPIVLSAHCNRVPVRD
GHLETVSLDLHRSATPAEVIDVLRAFRALPQELELPSAPRHPVIVLEEPDRPQPVLDRDAERGMASVVGRVRPCSVFDIR
FVVLGHNTIRGAAGASVLNAELFYREGLL

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=365, Percent_Identity=43.2876712328767, Blast_Score=278, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38245; Mature: 38114

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRIDVAILAATGSVGQRFVQLLAGHPWFRIAELVASDRSAGKRYAEAVNWRISAAPPE
CCCCEEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCEEEECCCHH
EVRDLVVKHIEEPINSPIVFSALPGGVAGPIEEALAAEGKKVFTNARDHRMDPDVPLLIP
HHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCHHHHCCCHHCCCCCCCCEEEC
EVNPDHARAIERQRQLRGWREGFIVANPNCSTIHLVLALKPIHDAFGIERGIVTTLQASS
CCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEHHHHHHCCCCCCEEEEECCC
GAGYPGVPSLDLIDNVIPYIGGEEEKIEAESRKILGRWIDGTFEDAPIVLSAHCNRVPVR
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
DGHLETVSLDLHRSATPAEVIDVLRAFRALPQELELPSAPRHPVIVLEEPDRPQPVLDRD
CCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCCCCCCCC
AERGMASVVGRVRPCSVFDIRFVVLGHNTIRGAAGASVLNAELFYREGLL
HHHHHHHHHCCCCCCEEEEEEEEEEECCHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDRIDVAILAATGSVGQRFVQLLAGHPWFRIAELVASDRSAGKRYAEAVNWRISAAPPE
CCCEEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCEEEECCCHH
EVRDLVVKHIEEPINSPIVFSALPGGVAGPIEEALAAEGKKVFTNARDHRMDPDVPLLIP
HHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCHHHHCCCHHCCCCCCCCEEEC
EVNPDHARAIERQRQLRGWREGFIVANPNCSTIHLVLALKPIHDAFGIERGIVTTLQASS
CCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEHHHHHHCCCCCCEEEEECCC
GAGYPGVPSLDLIDNVIPYIGGEEEKIEAESRKILGRWIDGTFEDAPIVLSAHCNRVPVR
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
DGHLETVSLDLHRSATPAEVIDVLRAFRALPQELELPSAPRHPVIVLEEPDRPQPVLDRD
CCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCEEEEECCCCCCCCCCCC
AERGMASVVGRVRPCSVFDIRFVVLGHNTIRGAAGASVLNAELFYREGLL
HHHHHHHHHCCCCCCEEEEEEEEEEECCHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]