Click here to switch to the map view.

The map label for this gene is prmA [H]

Identifier: 221632372

GI number: 221632372

Start: 347133

End: 348053

Strand: Reverse

Name: prmA [H]

Synonym: trd_0343

Alternate gene names: 221632372

Gene position: 348053-347133 (Counterclockwise)

Preceding gene: 221632373

Following gene: 221632371

Centisome position: 17.38

GC content: 64.6

Gene sequence:

>921_bases
ATGCCTGCGCGTTGGCTCGAAGTCGCTGTCGAGACTGATGCTGAGGTCGCCGATGCAGTCGCCGAACTGTTCGCCCGCTT
CGGCTACCAGCAGGGAGCCGCCGTCTTTCACCCGGTAGCACAGGATCCCGACGGAGAAAACGCGACCATCGATCCGGCGA
CTCCGGTTCTCATCGCGACCTATCTGCCGCTCGACGAGCAGGTCGATGCCACAGTCGAACGACTCCGACATGGGCTTTGG
CACCTGAGCCAACTCGGGCGTATCGGTGAACTTCGCCTGCGGACACTCGCCGAGGAGGAGTGGGCCGAGGCATGGAAGAG
CCATTTCCCGGTGACGCGCATCGGCCACCGGATCGTCATCCGGCCTTCCTGGATCCCTTACGAATCACGCGACGACGAGA
TCGTCGTTCACCTCGATCCTGGTATGGCCTTCGGAACGGGGCTCCACCCGACTACCCAGCACTGTCTCCTCTGGTTGGAA
CGCTTGGTCACCCCCGGCATGAGCGTCCTCGATGCTGGAGCTGGGTCGGGCATCCTTTCCATCGCTGCGCTCGCGCTCGG
TGCTCGGTCGGTCACGGCATGGGAAATCGATCCGGTTGCTGGCGAGGTCCTGCGGGAGAACCTGGAGCGGAACGGCGTCG
CCGATCGTGCGACGGTGCGCATCGGCGATGTCACCGAGGACCTCACTGATCGCGAGGCCTATGACCTCGTCGTGGCCAAT
ATCGTTGCCCGCGTCTTGATCGAAGCGGGGCCGCGCTTGGTGCGGGCTGCACGGCCCGGCGCTCACCTCGTCCTCAGCGG
CATCATCGACACAGCCGAGGAGGGAGTCCGTCGCCGTTATCACGATCTCGGCACTGAACTCGTCGAGCGCCGGCAGGACG
GTGATTGGGTGAGCCTGCTCCTGCGGCGGAATCGGCCATGA

Upstream 100 bases:

>100_bases
ATCGTCGGTCGCCGCGCCCGGGTACTCGGTGACTTCGTGCGCGTGAACGTCGGCGATTCCTCGGAGATCACCTTCTCCGG
ACGAGACGGAGCATGAGCTG

Downstream 100 bases:

>100_bases
GCCGGCGGGGCCATCGCTTCTTCGTGACCGAACATCTCGAACTCGGTGCTCGCGTCACCCTACCTCGGCGCGTGAGCCAT
CAGCTTGTCCGTGTCCTGCG

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPARWLEVAVETDAEVADAVAELFARFGYQQGAAVFHPVAQDPDGENATIDPATPVLIATYLPLDEQVDATVERLRHGLW
HLSQLGRIGELRLRTLAEEEWAEAWKSHFPVTRIGHRIVIRPSWIPYESRDDEIVVHLDPGMAFGTGLHPTTQHCLLWLE
RLVTPGMSVLDAGAGSGILSIAALALGARSVTAWEIDPVAGEVLRENLERNGVADRATVRIGDVTEDLTDREAYDLVVAN
IVARVLIEAGPRLVRAARPGAHLVLSGIIDTAEEGVRRRYHDLGTELVERRQDGDWVSLLLRRNRP

Sequences:

>Translated_306_residues
MPARWLEVAVETDAEVADAVAELFARFGYQQGAAVFHPVAQDPDGENATIDPATPVLIATYLPLDEQVDATVERLRHGLW
HLSQLGRIGELRLRTLAEEEWAEAWKSHFPVTRIGHRIVIRPSWIPYESRDDEIVVHLDPGMAFGTGLHPTTQHCLLWLE
RLVTPGMSVLDAGAGSGILSIAALALGARSVTAWEIDPVAGEVLRENLERNGVADRATVRIGDVTEDLTDREAYDLVVAN
IVARVLIEAGPRLVRAARPGAHLVLSGIIDTAEEGVRRRYHDLGTELVERRQDGDWVSLLLRRNRP
>Mature_305_residues
PARWLEVAVETDAEVADAVAELFARFGYQQGAAVFHPVAQDPDGENATIDPATPVLIATYLPLDEQVDATVERLRHGLWH
LSQLGRIGELRLRTLAEEEWAEAWKSHFPVTRIGHRIVIRPSWIPYESRDDEIVVHLDPGMAFGTGLHPTTQHCLLWLER
LVTPGMSVLDAGAGSGILSIAALALGARSVTAWEIDPVAGEVLRENLERNGVADRATVRIGDVTEDLTDREAYDLVVANI
VARVLIEAGPRLVRAARPGAHLVLSGIIDTAEEGVRRRYHDLGTELVERRQDGDWVSLLLRRNRP

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=162, Percent_Identity=44.4444444444444, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33800; Mature: 33669

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARWLEVAVETDAEVADAVAELFARFGYQQGAAVFHPVAQDPDGENATIDPATPVLIAT
CCCHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEECCCCCEEEEE
YLPLDEQVDATVERLRHGLWHLSQLGRIGELRLRTLAEEEWAEAWKSHFPVTRIGHRIVI
ECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEE
RPSWIPYESRDDEIVVHLDPGMAFGTGLHPTTQHCLLWLERLVTPGMSVLDAGAGSGILS
CCCCCCCCCCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
IAALALGARSVTAWEIDPVAGEVLRENLERNGVADRATVRIGDVTEDLTDREAYDLVVAN
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHEEEECCCHHHHHHHHHHHHHHHH
IVARVLIEAGPRLVRAARPGAHLVLSGIIDTAEEGVRRRYHDLGTELVERRQDGDWVSLL
HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LRRNRP
HHCCCC
>Mature Secondary Structure 
PARWLEVAVETDAEVADAVAELFARFGYQQGAAVFHPVAQDPDGENATIDPATPVLIAT
CCHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEECCCCCEEEEE
YLPLDEQVDATVERLRHGLWHLSQLGRIGELRLRTLAEEEWAEAWKSHFPVTRIGHRIVI
ECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEE
RPSWIPYESRDDEIVVHLDPGMAFGTGLHPTTQHCLLWLERLVTPGMSVLDAGAGSGILS
CCCCCCCCCCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
IAALALGARSVTAWEIDPVAGEVLRENLERNGVADRATVRIGDVTEDLTDREAYDLVVAN
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHEEEECCCHHHHHHHHHHHHHHHH
IVARVLIEAGPRLVRAARPGAHLVLSGIIDTAEEGVRRRYHDLGTELVERRQDGDWVSLL
HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LRRNRP
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA