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The map label for this gene is pcaI [H]

Identifier: 221632332

GI number: 221632332

Start: 305873

End: 306571

Strand: Reverse

Name: pcaI [H]

Synonym: trd_0303

Alternate gene names: 221632332

Gene position: 306571-305873 (Counterclockwise)

Preceding gene: 221632337

Following gene: 221632331

Centisome position: 15.31

GC content: 62.52

Gene sequence:

>699_bases
ATGGACAGAGTTGTCGCGAGTTGTGACGAAGCGGTCGCCGATATCCCGAACGGCGCATCGATCATGATCGGGGGTTTTGG
GCCGCCCGGAGTTCCCGTCAACCTGGTCCGGGCGCTTCGGCAGCGAGGGCTGCACGACCTCGTCCTCATCTACTGCGGTG
GCGGCACGGAGGAGGACGGCATCGGCGGACTGATCGCTGACGGTGCAGTCCGCAAGCTGATCACCTCGTTTCCAGTTCAC
CCTGGCGCACACGCGGTTCGGGAGCGCTATCTCCAGGGTGAGATCGAGCTGGAGGTCGTGCCCCAGGGGACATTCGTCGA
GCGTATCCGTGCGGCGGGAGCCGGCCTGGGTGGATTCTATTCCCCGACTGGCGTCGGAACCGAGTTGGCCGCAGGGAAAG
AAGTGCGCCTGATCGACGGACGCGCCTTTGTCTTGGAACTTCCGCTCCCAGCCGATTACGCCCTCATCAAGGCCTTTCGG
GCTGACCAGTGGGGCAACCTCGTCTACCGGCGCACCATGCGGAACTTCAATCCGATCATGGCCACAGCCGCTCGGATGGT
GATCGCTGAAGTCGATGAAGTCGTTCCGGTCGGTTCCCTCTCACCCGAGGAAATCGAAACACCGTGTCTTTTTGTCGACC
GAGTCGTTGAGGTGCCGCGTGACTGGTTCCGACACGCAACATCCGCTGAACGACGGTGA

Upstream 100 bases:

>100_bases
CCCCGCCCGCTTCGGCCGGTCATGCCTTGACAGCCTGTCGGAGGACATCGTATCATCCACATGGTCGCCAAGTTAATCCT
TAAAGGAAATGGTCGGACCG

Downstream 100 bases:

>100_bases
GGTGGTACTCGATGCCGCTGACACGCGAGGGAATTGCCTACCGTATCGCCCATGATCTCCCCGACGGCAGCTTCGTCAAC
CTCGGCTTCGGTATGCCGTC

Product: IpsJ protein

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MDRVVASCDEAVADIPNGASIMIGGFGPPGVPVNLVRALRQRGLHDLVLIYCGGGTEEDGIGGLIADGAVRKLITSFPVH
PGAHAVRERYLQGEIELEVVPQGTFVERIRAAGAGLGGFYSPTGVGTELAAGKEVRLIDGRAFVLELPLPADYALIKAFR
ADQWGNLVYRRTMRNFNPIMATAARMVIAEVDEVVPVGSLSPEEIETPCLFVDRVVEVPRDWFRHATSAERR

Sequences:

>Translated_232_residues
MDRVVASCDEAVADIPNGASIMIGGFGPPGVPVNLVRALRQRGLHDLVLIYCGGGTEEDGIGGLIADGAVRKLITSFPVH
PGAHAVRERYLQGEIELEVVPQGTFVERIRAAGAGLGGFYSPTGVGTELAAGKEVRLIDGRAFVLELPLPADYALIKAFR
ADQWGNLVYRRTMRNFNPIMATAARMVIAEVDEVVPVGSLSPEEIETPCLFVDRVVEVPRDWFRHATSAERR
>Mature_232_residues
MDRVVASCDEAVADIPNGASIMIGGFGPPGVPVNLVRALRQRGLHDLVLIYCGGGTEEDGIGGLIADGAVRKLITSFPVH
PGAHAVRERYLQGEIELEVVPQGTFVERIRAAGAGLGGFYSPTGVGTELAAGKEVRLIDGRAFVLELPLPADYALIKAFR
ADQWGNLVYRRTMRNFNPIMATAARMVIAEVDEVVPVGSLSPEEIETPCLFVDRVVEVPRDWFRHATSAERR

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=227, Percent_Identity=39.647577092511, Blast_Score=177, Evalue=8e-45,
Organism=Homo sapiens, GI11545841, Length=227, Percent_Identity=43.1718061674009, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1788551, Length=217, Percent_Identity=43.778801843318, Blast_Score=174, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17531517, Length=234, Percent_Identity=38.4615384615385, Blast_Score=169, Evalue=7e-43,
Organism=Drosophila melanogaster, GI21358325, Length=233, Percent_Identity=39.0557939914163, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24655794, Length=233, Percent_Identity=39.0557939914163, Blast_Score=178, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 25046; Mature: 25046

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVVASCDEAVADIPNGASIMIGGFGPPGVPVNLVRALRQRGLHDLVLIYCGGGTEEDG
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
IGGLIADGAVRKLITSFPVHPGAHAVRERYLQGEIELEVVPQGTFVERIRAAGAGLGGFY
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCC
SPTGVGTELAAGKEVRLIDGRAFVLELPLPADYALIKAFRADQWGNLVYRRTMRNFNPIM
CCCCCCCHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHH
ATAARMVIAEVDEVVPVGSLSPEEIETPCLFVDRVVEVPRDWFRHATSAERR
HHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MDRVVASCDEAVADIPNGASIMIGGFGPPGVPVNLVRALRQRGLHDLVLIYCGGGTEEDG
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
IGGLIADGAVRKLITSFPVHPGAHAVRERYLQGEIELEVVPQGTFVERIRAAGAGLGGFY
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCC
SPTGVGTELAAGKEVRLIDGRAFVLELPLPADYALIKAFRADQWGNLVYRRTMRNFNPIM
CCCCCCCHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHH
ATAARMVIAEVDEVVPVGSLSPEEIETPCLFVDRVVEVPRDWFRHATSAERR
HHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]