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The map label for this gene is treB [H]

Identifier: 221232619

GI number: 221232619

Start: 1841265

End: 1843232

Strand: Reverse

Name: treB [H]

Synonym: SPN23F_18970

Alternate gene names: 221232619

Gene position: 1843232-1841265 (Counterclockwise)

Preceding gene: 221232621

Following gene: 221232618

Centisome position: 82.98

GC content: 44.61

Gene sequence:

>1968_bases
ATGGGAAAATTTGAACAAGAAGCCAAAGATCTGCTTCAGGCAATTGGAGGCAAAGAAAATGTGACTGCCGTAACTCACTG
TGCGACACGGATGCGCTTTGTTTTAGGAGATGATAAGAAGGCTAATGTTAAAGCTATCGAGTCAATTCCAGCTGTTAAAG
GAACTTTTACAAATGCAGGTCAATTTCAGGTAATCATTGGAAATGACGTGCCCATCTTTTATAATGATTTTACAGCCGTT
TCAGGTATTGAGGGTGTTTCCAAAGAAGCAGCCAAGTCTGCAGCTAAGAGTAATCAAAACGTGGTCCAACGTGTTATGAC
CACTCTGGCGGAGATTTTTACTCCGATTATTCCAGCCTTGATAGTCGGAGGATTGATCCTCGGTTTCCGTAATGTCTTGG
AAGGTGTCCATTGGTCGATGTTGGATGGCAAGACCATCACAGAATCCTCTCAGTTTTGGGCAGGTGTCAATCACTTCCTC
TGGTTGCCTGGTGAAGCTATCTTCCAGTTCTTACCAGTAGGGATTACTTGGTCTGTTTCTCGTAAGATGGGAACCAGCCA
AATTTTGGGAATTGTTCTCGGAATCTGTTTGGTATCGCCTCAGTTGCTCAATGCCTATGCGGTTGCTTCAACGCCAGCAG
CTGATATCGCGGCAAACTGGGTTTGGAATTTTGGCTATTTTACTGTTAATCGTATCGGTTACCAAGCCCAAGTTATCCCA
GCCTTGCTTGCAGGTTTGAGTCTGTCTTATCTTGAAATCTTCTGGCGCAAGCATATCCCAGAAGTCATTTCTATGATTTT
TGTACCTTTCTTGTCATTGATTCCAGCCTTGATTTTGGCTCATACTGTTTTGGGACCAATCGGTTGGACAATTGGACAAG
GACTTTCATCAGTTGTCTTGGCAGGTTTAACTGGTCCAGTTAAAGGGCTCTTCGGTGCAATTTTTGGTGCCCTCTACGCT
CCATTTGTCATCACAGGTCTGCACCATATGACCAATGCCATTGATACACAATTGATTGCGGATGCTGGTGGCACTGCCCT
ATGGCCAATGATTGCTCTTTCTAATATTGCTCAAGGCTCAGCCGTGTTTGCCTATTATTTCATGCATCGCCATGATGAGC
GTGAGGCTCAGGTTTCACTTCCTGCAACCATTTCAGCCTATCTCGGTGTTACAGAACCAGCTCTTTTTGGGGTTAACGTA
AAATATATTTATCCATTTGTTGCTGGGATGACTGGTTCAGCCCTTGCAGGCATGTTATCCGTTACTTTTAATGTAACTGC
GGCTTCTATTGGTATCGGTGGTTTGCCAGGTATTCTCTCTATTCAACCTCAATACATGCTGCCATTTGCAGGAACTATGC
TAGTTGCGATTGTTGTTCCAATGCTCTTGACTTTCTTCTTCCGCAAGGCTGGTCTCTTTACAAAAACAGAGGGCGATACG
AACTTGCAGGCAGAATTCGTTGCTCAAGAAGAAGCAGAATTTGTGAACCATGAACCAGTAGAACTTACTTCGGTAGAAAT
TATCAGCCCACTAACTGGCCAAGTGAAAGAATTGAGTCAAGCGACGGATCCTATTTTTGCATCAGGTGTCATGGGGCAAG
GTCTGGTCATTGAACCAAGCCAAGGTGAGTTGACCTCTCCAGTTAATGGGACAGTGACGGTTCTTTTCCCTACCAAGCAT
GCCATCGGCATTGTCTCTGACGAGGGAGTTGAATTGCTCATCCACATCGGTATGGATACAGTAGGTCTTGATGGCAAAGG
TTTTGAAAGTCTTGTAGTCCAAGGAGATCACGTTACAGTTGGTCAGCAACTGATTCGTTTTGATATGGATGTCATTAAGG
CTGCAGGTCTGGTGACAGAAACTCCTGTTATCATCACCAACCAAGATGCTTATACAGCGACTATTCCCGGAACTTATCCG
ACAACGATTCAAGCTGGAGCATCTCTCATGGTCGCTACACGAATCTAA

Upstream 100 bases:

>100_bases
AAACACCCTTTTTATACCAAACAAGTTGCAGACAAGTTTGGTATCGTTTACAATATACTTATCAAATCAAACTTGCTTTG
ACAAGTATAAGGAGAATCAA

Downstream 100 bases:

>100_bases
TACTCTTCGAAAATCTCTTCAAACCACGTCAGCTCTATCTGCAACCTCAAAACAGTGTTTTGAGCAACCTGTGGCTAGCT
TCCTAGTTTGCTCTTTGATT

Product: sugar phosphotransferase system (PTS), IIABC component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAV
SGIEGVSKEAAKSAAKSNQNVVQRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIP
ALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYA
PFVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNV
KYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDT
NLQAEFVAQEEAEFVNHEPVELTSVEIISPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKH
AIGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATIPGTYP
TTIQAGASLMVATRI

Sequences:

>Translated_655_residues
MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAV
SGIEGVSKEAAKSAAKSNQNVVQRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIP
ALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYA
PFVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNV
KYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDT
NLQAEFVAQEEAEFVNHEPVELTSVEIISPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKH
AIGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATIPGTYP
TTIQAGASLMVATRI
>Mature_654_residues
GKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVS
GIEGVSKEAAKSAAKSNQNVVQRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFLW
LPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIPA
LLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAP
FVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNVK
YIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDTN
LQAEFVAQEEAEFVNHEPVELTSVEIISPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHA
IGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATIPGTYPT
TIQAGASLMVATRI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=447, Percent_Identity=50.1118568232662, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1790159, Length=662, Percent_Identity=30.5135951661631, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI48994906, Length=480, Percent_Identity=28.5416666666667, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1788757, Length=136, Percent_Identity=38.2352941176471, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786894, Length=137, Percent_Identity=36.4963503649635, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788769, Length=483, Percent_Identity=24.8447204968944, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69775; Mature: 69644

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAG
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCCCCCCCCC
QFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVVQRVMTTLAEIFTPIIPAL
EEEEEECCCCCEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFLWLPGEAIFQFLPVGITWSVS
HHHHHHHHHHHHHCCCCEEHCCCCEECCCHHHHHCCCCEEECCHHHHHHHHCCCEEEEEH
RKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIP
HHCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHEEECCCEEEECCCCHHHHHH
ALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVL
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
AVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNVKYIYPFVAGMTGSALAGMLS
HHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCHHCCCCHHEEHHHHHCCCHHHHHHHHH
VTFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDT
HEEEEEEEECCCCCCCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
NLQAEFVAQEEAEFVNHEPVELTSVEIISPLTGQVKELSQATDPIFASGVMGQGLVIEPS
CCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHCCCHHHCCCCCCCEEEECC
QGELTSPVNGTVTVLFPTKHAIGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTV
CCCCCCCCCCEEEEEEECCCEEEEECCCCCEEEEEECCCEECCCCCCCHHHEEECCCCHH
GQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATIPGTYPTTIQAGASLMVATRI
HHHHHHHHHHHHHHCCCEECCCEEEECCCCEEEECCCCCCCHHHCCCEEEEEECC
>Mature Secondary Structure 
GKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCCCCCCCCC
QFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVVQRVMTTLAEIFTPIIPAL
EEEEEECCCCCEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFLWLPGEAIFQFLPVGITWSVS
HHHHHHHHHHHHHCCCCEEHCCCCEECCCHHHHHCCCCEEECCHHHHHHHHCCCEEEEEH
RKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIP
HHCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHEEECCCEEEECCCCHHHHHH
ALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVL
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
AVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNVKYIYPFVAGMTGSALAGMLS
HHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCHHCCCCHHEEHHHHHCCCHHHHHHHHH
VTFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDT
HEEEEEEEECCCCCCCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
NLQAEFVAQEEAEFVNHEPVELTSVEIISPLTGQVKELSQATDPIFASGVMGQGLVIEPS
CCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHCCCHHHCCCCCCCEEEECC
QGELTSPVNGTVTVLFPTKHAIGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTV
CCCCCCCCCCEEEEEEECCCEEEEECCCCCEEEEEECCCEECCCCCCCHHHEEECCCCHH
GQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATIPGTYPTTIQAGASLMVATRI
HHHHHHHHHHHHHHCCCEECCCEEEECCCCEEEECCCCCCCHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]