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The map label for this gene is treA [H]

Identifier: 221232618

GI number: 221232618

Start: 1839462

End: 1841087

Strand: Reverse

Name: treA [H]

Synonym: SPN23F_18960

Alternate gene names: 221232618

Gene position: 1841087-1839462 (Counterclockwise)

Preceding gene: 221232619

Following gene: 221232617

Centisome position: 82.88

GC content: 41.88

Gene sequence:

>1626_bases
ATGACACTTGATAAAGGAAAAGTAGTCTATCAAATCTATCCAAAATCTTACAAAGACACCACTGAAAACGGTATTGGGGA
TTTCCGTGGGATTATCGAAAAAATTCCCTATTTAGCCAAACTAGGCGTGGATATGGTCTGGCTCAATCCATTCTATCCAA
GCCCTCAACGGGATAATGGTTACGATATTTCAGATTATATGGCAGTGGATCCTCTTTTTGGTGATATGGCTGATTTTGAG
GAAATGGTGTGTGTCGGTAAAGAGCACAAGATTGACTTTATGCTGGACATGGTACTTAATCATTGTTCGACAGAGCATGA
ATGGTTTCAGAAAGCCCTAGCTGGTGATAAGTATTATCAAGACTTTTTCTTCATCCAAGACCAACCAACAGATTGGCAGT
CTAAGTTTGGTGGTTCTGCATGGGCGCCTTTCGGGGATACTGGGAAATACTATCTTCACCTATTTGATGAGACCCAGGCT
GACCTTAACTGGCGCAATTCCAATGTCCGTAAGGAGCTTTTCAAGGTTGTTAATTTCTGGCGCGACAAGGGTGTCAAAGG
TTTCCGATTTGATGTGATCAATTTGATCGGTAAGGACGAGGTTTCAGTGGACTGTCCTGAAAATGAAGGGAAGCCAGCTT
ATACAGACAAACCCATCGTTCATAACTATTTGCGTATGATGAACCAAGCCACTTTTGGATCTGACGATAGCTTTATGACA
GTTGGGGAAATGTCTTCTACCACCATGGAAAACTGTGTCCTCTATTCGTCGCCTGATCGTCAGGAATTATCCATGACCTT
TAATTTTCATCACCTCAAGGTGGACTATAAGGATGGACAAAAGTGGACCTTGGCTCCCTTTGATTTTGAAGAGTTGAAGA
GTCTTTACCATAGTTGGGGTAAGGAAATGAGTGATAAAGACGGTTGGAGTGCCCTCTTTTGGAACAATCACGATCAACCA
CGTGCCTTGAACCGTTTTGTCGATATTCAAAACTTCCGCAAGGAAGGAGCCACCATGCTAGCGGCCAGCATTCACCTGTC
ACGTGGGACACCTTATATCTACATGGGTGAGGAAATCGGGATGATTGACCCAGACTATGATTCTATGGCTGATTATGTGG
ATGTCGAATCGCTTAATGCCTATCAGATGCTCTTAGAAGAAGGAAAGAGTCAGCAAGAAGCCTTCCAGATTATTCAAGCT
AAGTCGCGTGATAATTCACGCATTCCCATGCAGTGGGATGCTTCGGAAAATGCAGGATTTTCAACAGGCACTCCTTGGTT
GAAAGCTGGTAAATCCTATAAAGACATCAATGTAGAAAATGAAATCCAGGGTCCGATTTTTACCTTCTATCAAGACTTGA
TTCGACTGCGTAAGGAAATGCCAATCATTTCAGAAGGAAGTTACAAACCAGCCTTTGAAGATAGCAAACAAGTCTACGCT
TTTGAACGCCAGTTTGAGGATCAAAAGTTACTAGTGCTCAATAACTTTTATGCTAAAGAAGTGGAAATCGACTTGCCAGC
AGTCTACCAAAATGGACAGATTTTGATTTCAAACTATGAAGATGCAGAAGTGTCTGAGAAAATTCTACTCAAACCCTATC
AAACACTGGCTATTTATGTAAATTAA

Upstream 100 bases:

>100_bases
GCTTCCTAGTTTGCTCTTTGATTTTCATTGAGTATAATTGAAATAGCACAAATAGGGACGGAAGACTGCTTCCTCCCTTT
TATCAGAAAAGGAGAAACAG

Downstream 100 bases:

>100_bases
TACTCTTCGAAAATCTCTTCAAACCGTGTCAGTTTTATCTGCAACCTCAAAGCGGTGCTTTGAGCAACCTGTGGCTAGCT
TCCTAGTTTGCTCTTTGATT

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFE
EMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQP
RALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQA
KSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN

Sequences:

>Translated_541_residues
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFE
EMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQP
RALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQA
KSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN
>Mature_540_residues
TLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEE
MVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQAD
LNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMTV
GEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPR
ALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAK
SRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYAF
ERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYVN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=524, Percent_Identity=27.8625954198473, Blast_Score=185, Evalue=9e-47,
Organism=Escherichia coli, GI1790687, Length=537, Percent_Identity=46.927374301676, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1786604, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32565753, Length=196, Percent_Identity=29.0816326530612, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147709, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=34.5486111111111, Blast_Score=309, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=34.5486111111111, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=34.5486111111111, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=34.5486111111111, Blast_Score=305, Evalue=9e-84,
Organism=Saccharomyces cerevisiae, GI6321731, Length=568, Percent_Identity=34.330985915493, Blast_Score=299, Evalue=9e-82,
Organism=Saccharomyces cerevisiae, GI6319776, Length=568, Percent_Identity=34.1549295774648, Blast_Score=297, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6322245, Length=562, Percent_Identity=32.0284697508897, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24586591, Length=567, Percent_Identity=32.8042328042328, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24586593, Length=530, Percent_Identity=31.8867924528302, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24583745, Length=579, Percent_Identity=30.0518134715026, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24583747, Length=537, Percent_Identity=32.9608938547486, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24583749, Length=537, Percent_Identity=32.9608938547486, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI221330053, Length=585, Percent_Identity=30.4273504273504, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI45549022, Length=572, Percent_Identity=31.4685314685315, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24586589, Length=541, Percent_Identity=31.2384473197782, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24586599, Length=537, Percent_Identity=30.7262569832402, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=30.2631578947368, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24586587, Length=577, Percent_Identity=25.6499133448873, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281360393, Length=482, Percent_Identity=30.0829875518672, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 62770; Mature: 62639

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNG
CCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCC
YDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQ
CCHHHHEEECCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
DFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQADLNWRNSNVRKELFKVVNFW
EEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
HHCCCCCEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWG
ECCCCCCCHHCEEEECCCCCCEEEEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHC
KEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCCCC
MIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAKSRDNSRIPMQWDASENAGF
CCCCCHHHHHHHHCHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
STGTPWLKAGKSYKDINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
CCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEH
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYV
HHHCCCCCEEEEEECCEEEEEEEECCEEECCCEEEEECCCCCHHHHHHHCCCCEEEEEEE
N
C
>Mature Secondary Structure 
TLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVDMVWLNPFYPSPQRDNG
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCCC
YDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHCSTEHEWFQKALAGDKYYQ
CCHHHHEEECCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
DFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQADLNWRNSNVRKELFKVVNFW
EEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKPIVHNYLRMMNQATFGSDDSFMT
HHCCCCCEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDYKDGQKWTLAPFDFEELKSLYHSWG
ECCCCCCCHHCEEEECCCCCCEEEEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHC
KEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRKEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCCCC
MIDPDYDSMADYVDVESLNAYQMLLEEGKSQQEAFQIIQAKSRDNSRIPMQWDASENAGF
CCCCCHHHHHHHHCHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
STGTPWLKAGKSYKDINVENEIQGPIFTFYQDLIRLRKEMPIISEGSYKPAFEDSKQVYA
CCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEH
FERQFEDQKLLVLNNFYAKEVEIDLPAVYQNGQILISNYEDAEVSEKILLKPYQTLAIYV
HHHCCCCCEEEEEECCEEEEEEEECCEEECCCEEEEECCCCCHHHHHHHCCCCEEEEEEE
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]