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The map label for this gene is pimB [H]

Identifier: 220933112

GI number: 220933112

Start: 2488625

End: 2489704

Strand: Reverse

Name: pimB [H]

Synonym: Hore_22800

Alternate gene names: 220933112

Gene position: 2489704-2488625 (Counterclockwise)

Preceding gene: 220933113

Following gene: 220933111

Centisome position: 96.57

GC content: 25.46

Gene sequence:

>1080_bases
ATGGATAAAAAAATAACAATATTTACTCCTTATTTATCAAAAACAATGGGTGGAATTCAAAATTTATCTTTCAATCTATT
TAAGTATTTAAAAGAATATGTTAAAGTTTCTGCATATTCAGGGAATATAAATGATGAAAAAATCAAAGGTGTTTATTACT
CAAAATATAATAATTCACAAATTAAAATAGGTTATGACTTATTTAAGAAGTCATATTACGACTTTAAGAAAAACAAAAGT
TACATTAATATTGCTTTAACTTGGAAACTAGGAATAATAACTTATTTATTAAAGATATTATATAATATTCCTTATATAGT
TTATGTACATGGAAATGATATTTACCCTGACAATAAAAATTTTGTTGAAAAATTTGTGATAAAAAGAGTCTTAAAGAATG
CGAATAAAATAATTGCTAATAGTAAATTTACAAAAAAATTATGCAATACATATGGTGAATTTAACATAAAAGTAATTCAC
CCTGGAATTGATTATAAAAATATAAAGATTGATAATAAAAACAAAGTCAAAAATAGGAAAATATTGTTTACGTTATCACG
ATTAGAGCAAAGAAAGGGTATTGATAATACTCTCAGAGCTATGCCTGAAATAATATCTAGATATCCAGATATCCATTATT
ATATCGGGGGGAAAGGTCCATATAATAAAATACTAAAACAAATTGTTAGTGAATTGAATATTGAAAACTATGTTACATTT
TTAGGTTTTATTTCAGAAGAACAAAAAGATGAAATGTATAAAAAGTGTGATTTGTTTGTTATGCCGAGCTATGAGGTTAA
AAAAGATGGAAGTGTAGAAGGTTTTGGAATAGTATATTTAGAAGCTAATATGTATGGTAAGTTTGTGATAGCAGGTAATT
CAGGAGGGATTTTGGATGCAGTAAACCATGGTAAGACCGGGTTGATAGTTGATGGTGGCGATCCTAAAAGTATATCTGAG
GGAATTATAAAGTTTTATGAAGAATATTATAACAAAAAGAATTACCAAGAAGATTGTATAAGATGGGCGGAAAAGCATGA
TTGGAATAATATAATTAATCAAGTGTTAGATTTATTATAA

Upstream 100 bases:

>100_bases
ATTTTTTATTCTATATAAGGGTAAAGGTTATATTAAATATTGATACGGTTTTTTTATTTTAATATAGATTTTATTTGTCT
ACCTATGAGGTGTTGTAGAT

Downstream 100 bases:

>100_bases
CTCAATATACTTAAACTTATCTATGGAGGAATTTAAATGAGATCTGAATTAGTTTCAGTAATTACTCCACTTTATAATTC
AGAACAGTTTATTGAAAAGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDKKITIFTPYLSKTMGGIQNLSFNLFKYLKEYVKVSAYSGNINDEKIKGVYYSKYNNSQIKIGYDLFKKSYYDFKKNKS
YINIALTWKLGIITYLLKILYNIPYIVYVHGNDIYPDNKNFVEKFVIKRVLKNANKIIANSKFTKKLCNTYGEFNIKVIH
PGIDYKNIKIDNKNKVKNRKILFTLSRLEQRKGIDNTLRAMPEIISRYPDIHYYIGGKGPYNKILKQIVSELNIENYVTF
LGFISEEQKDEMYKKCDLFVMPSYEVKKDGSVEGFGIVYLEANMYGKFVIAGNSGGILDAVNHGKTGLIVDGGDPKSISE
GIIKFYEEYYNKKNYQEDCIRWAEKHDWNNIINQVLDLL

Sequences:

>Translated_359_residues
MDKKITIFTPYLSKTMGGIQNLSFNLFKYLKEYVKVSAYSGNINDEKIKGVYYSKYNNSQIKIGYDLFKKSYYDFKKNKS
YINIALTWKLGIITYLLKILYNIPYIVYVHGNDIYPDNKNFVEKFVIKRVLKNANKIIANSKFTKKLCNTYGEFNIKVIH
PGIDYKNIKIDNKNKVKNRKILFTLSRLEQRKGIDNTLRAMPEIISRYPDIHYYIGGKGPYNKILKQIVSELNIENYVTF
LGFISEEQKDEMYKKCDLFVMPSYEVKKDGSVEGFGIVYLEANMYGKFVIAGNSGGILDAVNHGKTGLIVDGGDPKSISE
GIIKFYEEYYNKKNYQEDCIRWAEKHDWNNIINQVLDLL
>Mature_359_residues
MDKKITIFTPYLSKTMGGIQNLSFNLFKYLKEYVKVSAYSGNINDEKIKGVYYSKYNNSQIKIGYDLFKKSYYDFKKNKS
YINIALTWKLGIITYLLKILYNIPYIVYVHGNDIYPDNKNFVEKFVIKRVLKNANKIIANSKFTKKLCNTYGEFNIKVIH
PGIDYKNIKIDNKNKVKNRKILFTLSRLEQRKGIDNTLRAMPEIISRYPDIHYYIGGKGPYNKILKQIVSELNIENYVTF
LGFISEEQKDEMYKKCDLFVMPSYEVKKDGSVEGFGIVYLEANMYGKFVIAGNSGGILDAVNHGKTGLIVDGGDPKSISE
GIIKFYEEYYNKKNYQEDCIRWAEKHDWNNIINQVLDLL

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=218, Percent_Identity=27.9816513761468, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788357, Length=133, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 41788; Mature: 41788

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKITIFTPYLSKTMGGIQNLSFNLFKYLKEYVKVSAYSGNINDEKIKGVYYSKYNNSQ
CCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCHHCCEEEEEECCCCE
IKIGYDLFKKSYYDFKKNKSYINIALTWKLGIITYLLKILYNIPYIVYVHGNDIYPDNKN
EEEHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
FVEKFVIKRVLKNANKIIANSKFTKKLCNTYGEFNIKVIHPGIDYKNIKIDNKNKVKNRK
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCE
ILFTLSRLEQRKGIDNTLRAMPEIISRYPDIHYYIGGKGPYNKILKQIVSELNIENYVTF
EEEEHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHH
LGFISEEQKDEMYKKCDLFVMPSYEVKKDGSVEGFGIVYLEANMYGKFVIAGNSGGILDA
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEC
VNHGKTGLIVDGGDPKSISEGIIKFYEEYYNKKNYQEDCIRWAEKHDWNNIINQVLDLL
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHC
>Mature Secondary Structure
MDKKITIFTPYLSKTMGGIQNLSFNLFKYLKEYVKVSAYSGNINDEKIKGVYYSKYNNSQ
CCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCHHCCEEEEEECCCCE
IKIGYDLFKKSYYDFKKNKSYINIALTWKLGIITYLLKILYNIPYIVYVHGNDIYPDNKN
EEEHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
FVEKFVIKRVLKNANKIIANSKFTKKLCNTYGEFNIKVIHPGIDYKNIKIDNKNKVKNRK
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCE
ILFTLSRLEQRKGIDNTLRAMPEIISRYPDIHYYIGGKGPYNKILKQIVSELNIENYVTF
EEEEHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHH
LGFISEEQKDEMYKKCDLFVMPSYEVKKDGSVEGFGIVYLEANMYGKFVIAGNSGGILDA
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEC
VNHGKTGLIVDGGDPKSISEGIIKFYEEYYNKKNYQEDCIRWAEKHDWNNIINQVLDLL
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA