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The map label for this gene is xylR [H]

Identifier: 220933107

GI number: 220933107

Start: 2483324

End: 2484514

Strand: Reverse

Name: xylR [H]

Synonym: Hore_22750

Alternate gene names: 220933107

Gene position: 2484514-2483324 (Counterclockwise)

Preceding gene: 220933108

Following gene: 220933106

Centisome position: 96.37

GC content: 45.0

Gene sequence:

>1191_bases
GTGAAAAAAGTGTATCCGGTCAGCTACAAATTACAGAAAGGTATGAATGAAAAGTTAATTTTGAATATTATCAGAAGGGA
TGGACCCATCTCCAGGGCTGATATATCCAAAAAAACCAATCTGACCCCTCCTACCGTTACCAATGTTATTAATAAACTGG
TTGAAGAGAACCTGGTCCTGGAAGATATCATGGGGGAATCTAGTGGCGGAAGGCCCCCTCAGCTGGTCAGGCTGAACCCT
GAAGCCTTTAATATAGTGGTCACCCATGTCAGTTCAAACAAATTGACAGGTTATTTGACTGATGCCTATCTGAAAGTTAG
CAAAAAAGTTGTTTATGATATAGAAAGACTGGAAAAGCAGAAGATACTGGATTTGATGTTTGAAGTAATCGATGAATTAA
TAAAATCAGCCTCACAGGAGGTACCTGCCCTTGGGGTGGTTGTCCACGGCCCGGTTAAAGCCCGGGAGGGTGTTTCTGTC
TTTGCCCCCAATATAGGGTGGCGTAATGTTCCCATCAAAAAACTGGTTCAGGAGAGATTTAAAAAACCTGTCTGTGTTGA
GAATGACGTCAGGGCCATGGGGCTTGGAGAGTTTTATTATGGTTCCGGCAAGGGTGTTGATAACCTGGTCTTTTTAAAGA
TCGGGTATGGAATAGGTTCAGCCATTATCTTTGACGGGAAGATATTCCGGGGAATCAGTGATAGTGCCGGTGAGTTCGGC
CACACTACGGTGGATATAGGTGGCCCCCGGTGTAACTGTGGTAACTATGGCTGCCTTGAAGCCCTCTCTTCTGAAAATGC
CATTGTTAAAGCGGTGGTAAAAGATTTGAAGGCAGGCCGGATGTCCCTGGTAAGGGAGCTCTGTGATGGGAATCTGGAGA
AAGTAACTCCTGACCACGTTTACCGGGCCGCCGACCGGGGAGATGAGTTGAGCCTGTCTGTATTACAGGAGGCAGCGCGG
TATCTGGGTATAGGGATTGCCAACATTATTAATTCTATAAACCCCAAGGTGATTGTTATCGGCGGGGGTATCATCAAGGC
CCGACTCCACATTGAAGAGATTATAAACAAAAGTGTTGAAGAAAGGGCATTAACTAATGCCTATCAATCCTGTGATATTG
TCTTTTCAGAACTGGGTGATATCGGGACCCTGAAAGGGGCCGGAAATATAGTCATGGATGAAATATTATAA

Upstream 100 bases:

>100_bases
TTTTTAAAAAATTTTTAAAAAAAGAAGGAAAATTGATATTTATGTAGTATATTATAAATAGACTTTATTAAAATGAATAA
TAAAGTAGGAGGGACAGTCA

Downstream 100 bases:

>100_bases
ATAGACCTATTACAGTAAGAACAGGGGGAATTAAAGATGTTAGTATCATCTAAGGAAATGTTACAAAAAGCCATGAAAGA
AGGTTATGCCATTGCTTCTT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKKVYPVSYKLQKGMNEKLILNIIRRDGPISRADISKKTNLTPPTVTNVINKLVEENLVLEDIMGESSGGRPPQLVRLNP
EAFNIVVTHVSSNKLTGYLTDAYLKVSKKVVYDIERLEKQKILDLMFEVIDELIKSASQEVPALGVVVHGPVKAREGVSV
FAPNIGWRNVPIKKLVQERFKKPVCVENDVRAMGLGEFYYGSGKGVDNLVFLKIGYGIGSAIIFDGKIFRGISDSAGEFG
HTTVDIGGPRCNCGNYGCLEALSSENAIVKAVVKDLKAGRMSLVRELCDGNLEKVTPDHVYRAADRGDELSLSVLQEAAR
YLGIGIANIINSINPKVIVIGGGIIKARLHIEEIINKSVEERALTNAYQSCDIVFSELGDIGTLKGAGNIVMDEIL

Sequences:

>Translated_396_residues
MKKVYPVSYKLQKGMNEKLILNIIRRDGPISRADISKKTNLTPPTVTNVINKLVEENLVLEDIMGESSGGRPPQLVRLNP
EAFNIVVTHVSSNKLTGYLTDAYLKVSKKVVYDIERLEKQKILDLMFEVIDELIKSASQEVPALGVVVHGPVKAREGVSV
FAPNIGWRNVPIKKLVQERFKKPVCVENDVRAMGLGEFYYGSGKGVDNLVFLKIGYGIGSAIIFDGKIFRGISDSAGEFG
HTTVDIGGPRCNCGNYGCLEALSSENAIVKAVVKDLKAGRMSLVRELCDGNLEKVTPDHVYRAADRGDELSLSVLQEAAR
YLGIGIANIINSINPKVIVIGGGIIKARLHIEEIINKSVEERALTNAYQSCDIVFSELGDIGTLKGAGNIVMDEIL
>Mature_396_residues
MKKVYPVSYKLQKGMNEKLILNIIRRDGPISRADISKKTNLTPPTVTNVINKLVEENLVLEDIMGESSGGRPPQLVRLNP
EAFNIVVTHVSSNKLTGYLTDAYLKVSKKVVYDIERLEKQKILDLMFEVIDELIKSASQEVPALGVVVHGPVKAREGVSV
FAPNIGWRNVPIKKLVQERFKKPVCVENDVRAMGLGEFYYGSGKGVDNLVFLKIGYGIGSAIIFDGKIFRGISDSAGEFG
HTTVDIGGPRCNCGNYGCLEALSSENAIVKAVVKDLKAGRMSLVRELCDGNLEKVTPDHVYRAADRGDELSLSVLQEAAR
YLGIGIANIINSINPKVIVIGGGIIKARLHIEEIINKSVEERALTNAYQSCDIVFSELGDIGTLKGAGNIVMDEIL

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=232, Percent_Identity=31.8965517241379, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI190014632, Length=232, Percent_Identity=31.8965517241379, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4885285, Length=232, Percent_Identity=31.8965517241379, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI298566315, Length=232, Percent_Identity=31.8965517241379, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI298566312, Length=125, Percent_Identity=32.8, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1786891, Length=371, Percent_Identity=30.7277628032345, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787878, Length=381, Percent_Identity=24.9343832020997, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082127, Length=332, Percent_Identity=25, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87082230, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081733, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43238; Mature: 43238

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYPVSYKLQKGMNEKLILNIIRRDGPISRADISKKTNLTPPTVTNVINKLVEENLVL
CCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
EDIMGESSGGRPPQLVRLNPEAFNIVVTHVSSNKLTGYLTDAYLKVSKKVVYDIERLEKQ
HHHHCCCCCCCCCEEEEECCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
KILDLMFEVIDELIKSASQEVPALGVVVHGPVKAREGVSVFAPNIGWRNVPIKKLVQERF
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHC
KKPVCVENDVRAMGLGEFYYGSGKGVDNLVFLKIGYGIGSAIIFDGKIFRGISDSAGEFG
CCCCCCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCCCEEEECCHHHCCCCCCCCCCC
HTTVDIGGPRCNCGNYGCLEALSSENAIVKAVVKDLKAGRMSLVRELCDGNLEKVTPDHV
CEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
YRAADRGDELSLSVLQEAARYLGIGIANIINSINPKVIVIGGGIIKARLHIEEIINKSVE
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHHHHH
ERALTNAYQSCDIVFSELGDIGTLKGAGNIVMDEIL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MKKVYPVSYKLQKGMNEKLILNIIRRDGPISRADISKKTNLTPPTVTNVINKLVEENLVL
CCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
EDIMGESSGGRPPQLVRLNPEAFNIVVTHVSSNKLTGYLTDAYLKVSKKVVYDIERLEKQ
HHHHCCCCCCCCCEEEEECCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
KILDLMFEVIDELIKSASQEVPALGVVVHGPVKAREGVSVFAPNIGWRNVPIKKLVQERF
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHC
KKPVCVENDVRAMGLGEFYYGSGKGVDNLVFLKIGYGIGSAIIFDGKIFRGISDSAGEFG
CCCCCCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCCCEEEECCHHHCCCCCCCCCCC
HTTVDIGGPRCNCGNYGCLEALSSENAIVKAVVKDLKAGRMSLVRELCDGNLEKVTPDHV
CEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
YRAADRGDELSLSVLQEAARYLGIGIANIINSINPKVIVIGGGIIKARLHIEEIINKSVE
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHHHHH
ERALTNAYQSCDIVFSELGDIGTLKGAGNIVMDEIL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]