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The map label for this gene is kbaY [H]

Identifier: 220933106

GI number: 220933106

Start: 2482436

End: 2483287

Strand: Reverse

Name: kbaY [H]

Synonym: Hore_22740

Alternate gene names: 220933106

Gene position: 2483287-2482436 (Counterclockwise)

Preceding gene: 220933107

Following gene: 220933105

Centisome position: 96.32

GC content: 46.01

Gene sequence:

>852_bases
ATGTTAGTATCATCTAAGGAAATGTTACAAAAAGCCATGAAAGAAGGTTATGCCATTGCTTCTTTCAATGTACATAACCT
GGAGACCTTTAAGGGAGTAATGGAAGGCGGGATTAAAGAAAAAGCCCCGGTAATTATTCAGACTACTCCGGGTACCCTGA
GGCATGTTGGAATCAGGTATATGGTGGCCATGGCCAGGGCTGCTCAGCATGAGTATGATATCCCCTTTGCCCTCCATCTC
GACCACTGTACTGATATTGAGACCATTAAAAAATGTATCGACCTGGGTTATACTTCAGTCATGGTTGATGGTTCTAAACT
GCCTTTTGAAGAAAATATAGCCTTTACTAAAGAGGTAGTTGCCTATGCCCGGGACAGGGGTGTTCAGGTTGAAGCCGAAC
TGGGCAAGATAGGTGGTCAGGAAGATGACTTAAAGGTGGATGAGAGGGAAGCTACCCTGACTGACCCGGATAAGGCTGTT
GAGTTTGTCGACAGGACCGGGGTTGATTCCCTGGCTATAGCCATCGGTACCGCCCACGGGATGTATAAGGGTGACCCTGA
GATTGATTATAAGAGGTTGCAGACCATTAAAGGAAAGCTGGAGGTACCCATTGTCCTCCATGGGGCTTCAGGATTAAAAG
ATGATGTCATCGAAAAAACGGTCCAGTTTGGTGTCAATAAGGTTAATATAGCCACTGACCTTAAAAATGCCTTCGGGGCT
GCCCTGAAGACCCACTTCAGGGAAAAACCAGAGGAACTGGACCCCAGGAAGTACTTTAAGACAGCCAGGAAGGCTATTTC
TGAGGTAACCGCCCATAAGATAAGGCTTACCGGCAGTAATAATAAAGCATAA

Upstream 100 bases:

>100_bases
AGAACTGGGTGATATCGGGACCCTGAAAGGGGCCGGAAATATAGTCATGGATGAAATATTATAAATAGACCTATTACAGT
AAGAACAGGGGGAATTAAAG

Downstream 100 bases:

>100_bases
ATGTAATTAAAGTTGTTTCATCAGGAGCTTTCATAAATAGAGTATCGATAGTTAATTTTCAGGTGTGGACTTTAAACCGG
GGGGTTTTTTGCCGGAGATA

Product: ketose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Ketose 1,6-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLVSSKEMLQKAMKEGYAIASFNVHNLETFKGVMEGGIKEKAPVIIQTTPGTLRHVGIRYMVAMARAAQHEYDIPFALHL
DHCTDIETIKKCIDLGYTSVMVDGSKLPFEENIAFTKEVVAYARDRGVQVEAELGKIGGQEDDLKVDEREATLTDPDKAV
EFVDRTGVDSLAIAIGTAHGMYKGDPEIDYKRLQTIKGKLEVPIVLHGASGLKDDVIEKTVQFGVNKVNIATDLKNAFGA
ALKTHFREKPEELDPRKYFKTARKAISEVTAHKIRLTGSNNKA

Sequences:

>Translated_283_residues
MLVSSKEMLQKAMKEGYAIASFNVHNLETFKGVMEGGIKEKAPVIIQTTPGTLRHVGIRYMVAMARAAQHEYDIPFALHL
DHCTDIETIKKCIDLGYTSVMVDGSKLPFEENIAFTKEVVAYARDRGVQVEAELGKIGGQEDDLKVDEREATLTDPDKAV
EFVDRTGVDSLAIAIGTAHGMYKGDPEIDYKRLQTIKGKLEVPIVLHGASGLKDDVIEKTVQFGVNKVNIATDLKNAFGA
ALKTHFREKPEELDPRKYFKTARKAISEVTAHKIRLTGSNNKA
>Mature_283_residues
MLVSSKEMLQKAMKEGYAIASFNVHNLETFKGVMEGGIKEKAPVIIQTTPGTLRHVGIRYMVAMARAAQHEYDIPFALHL
DHCTDIETIKKCIDLGYTSVMVDGSKLPFEENIAFTKEVVAYARDRGVQVEAELGKIGGQEDDLKVDEREATLTDPDKAV
EFVDRTGVDSLAIAIGTAHGMYKGDPEIDYKRLQTIKGKLEVPIVLHGASGLKDDVIEKTVQFGVNKVNIATDLKNAFGA
ALKTHFREKPEELDPRKYFKTARKAISEVTAHKIRLTGSNNKA

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=282, Percent_Identity=47.1631205673759, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1789526, Length=281, Percent_Identity=45.1957295373665, Blast_Score=277, Evalue=4e-76,
Organism=Escherichia coli, GI1788072, Length=289, Percent_Identity=37.7162629757785, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1789293, Length=287, Percent_Identity=26.1324041811847, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=322, Percent_Identity=25.776397515528, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 31274; Mature: 31274

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSSKEMLQKAMKEGYAIASFNVHNLETFKGVMEGGIKEKAPVIIQTTPGTLRHVGIRY
CCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHH
MVAMARAAQHEYDIPFALHLDHCTDIETIKKCIDLGYTSVMVDGSKLPFEENIAFTKEVV
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
AYARDRGVQVEAELGKIGGQEDDLKVDEREATLTDPDKAVEFVDRTGVDSLAIAIGTAHG
HHHHCCCCEEEEHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHEEECCCC
MYKGDPEIDYKRLQTIKGKLEVPIVLHGASGLKDDVIEKTVQFGVNKVNIATDLKNAFGA
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
ALKTHFREKPEELDPRKYFKTARKAISEVTAHKIRLTGSNNKA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCC
>Mature Secondary Structure
MLVSSKEMLQKAMKEGYAIASFNVHNLETFKGVMEGGIKEKAPVIIQTTPGTLRHVGIRY
CCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHH
MVAMARAAQHEYDIPFALHLDHCTDIETIKKCIDLGYTSVMVDGSKLPFEENIAFTKEVV
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
AYARDRGVQVEAELGKIGGQEDDLKVDEREATLTDPDKAVEFVDRTGVDSLAIAIGTAHG
HHHHCCCCEEEEHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHEEECCCC
MYKGDPEIDYKRLQTIKGKLEVPIVLHGASGLKDDVIEKTVQFGVNKVNIATDLKNAFGA
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
ALKTHFREKPEELDPRKYFKTARKAISEVTAHKIRLTGSNNKA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA